Search Results - "Petersen, Teun B"
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Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum
Published in Scientific reports (27-06-2024)“…Circulating proteins may provide insights into the varying biological mechanisms involved in heart failure (HF) with preserved ejection fraction (HFpEF) and…”
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Sex-based differences in cardiovascular proteomic profiles and their associations with adverse outcomes in patients with chronic heart failure
Published in Biology of sex differences (17-05-2023)“…Studies focusing on sex differences in circulating proteins in patients with heart failure with reduced ejection fraction (HFrEF) are scarce. Insight into…”
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Proteomic biomarkers related to obesity in heart failure with reduced ejection fraction and their associations with outcome
Published in Obesity (Silver Spring, Md.) (01-09-2024)“…Objective Heart failure (HF) pathophysiology in patients with obesity may be distinct. To study these features, we identified obesity‐related biomarkers from…”
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Heart failure subphenotypes based on repeated biomarker measurements are associated with clinical characteristics and adverse events (Bio-SHiFT study)
Published in International journal of cardiology (01-10-2022)“…This study aimed to identify heart failure (HF) subphenotypes using 92 repeatedly measured circulating proteins in 250 patients with heart failure with reduced…”
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HFrEF subphenotypes based on 4210 repeatedly measured circulating proteins are driven by different biological mechanisms
Published in EBioMedicine (01-07-2023)“…HFrEF is a heterogenous condition with high mortality. We used serial assessments of 4210 circulating proteins to identify distinct novel protein-based HFrEF…”
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Machine learning–based biomarker profile derived from 4210 serially measured proteins predicts clinical outcome of patients with heart failure
Published in European heart journal. Digital health (01-12-2023)“…AimsRisk assessment tools are needed for timely identification of patients with heart failure (HF) with reduced ejection fraction (HFrEF) who are at high risk…”
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Abstract 12012: Subphenotypes of Heart Failure With Reduced Ejection Fraction Based on Repeated Measurements of 4210 Circulating Proteins Are Driven by Protein Subsets Reflecting Different Biological Mechanisms
Published in Circulation (New York, N.Y.) (08-11-2022)“…IntroductionSubphenotyping of HF may lead to pathophysiological insights and treatment opportunities. We aimed to identify novel circulating-protein based…”
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HFrEF subphenotypes based on 4210 repeatedly measured circulating proteins are driven by different biological mechanismsResearch in context
Published in EBioMedicine (01-07-2023)“…Background: HFrEF is a heterogenous condition with high mortality. We used serial assessments of 4210 circulating proteins to identify distinct novel…”
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