Search Results - "Peters, Wilbert Hm"

Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial by Pickkers, Peter, Heemskerk, Suzanne, Schouten, Jeroen, Laterre, Pierre-François, Vincent, Jean-Louis, Beishuizen, Albertus, Jorens, Philippe G, Spapen, Herbert, Bulitta, Michael, Peters, Wilbert H M, van der Hoeven, Johannes G

“…To evaluate whether alkaline phosphatase (AP) treatment improves renal function in sepsis-induced acute kidney injury (AKI), a prospective, double-blind,…”
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Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno- or squamous cell carcinoma by Kristinsson, Jón O, van Westerveld, Paul, te Morsche, Rene H M, Roelofs, Hennie M J, Wobbes, T, Witteman, Ben J M, Tan, Adriaan C I T L, van Oijen, Martijn G H, Jansen, Jan B M J, Peters, Wilbert H M

“…AIM： TO determine whether -1195 A→G and/or -765 G→C polymorphisms in Cyclooxygenase-2 CCOX-2） may have a risk modifying effect on the development of esophageal…”
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Assessment of oxidative stress in chronic pancreatitis patients by Verlaan, Mariette, Roelofs, Hennie M J, van-Schaik, Annie, Wanten, Geert J A, Jansen, Jan B M J, Peters, Wilbert H M, Drenth, Joost P H

“…AIM： To assess the levels of antioxidant capacity and oxidative damage in blood of chronic pancreatitis （CP） patients in comparison with those in healthy…”
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Over-expression of COX-2 mRNA in colorectal cancer by Roelofs, Hennie M J, Te Morsche, Rene H M, van Heumen, Bjorn W H, Nagengast, Fokko M, Peters, Wilbert H M

“…Cyclooxygenase-2 (COX-2, PTGS2) is an enzyme involved in the synthesis of prostaglandins and thromboxanes, which are regulators of biologic processes such as…”
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Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: a Dutch Caucasian case-control study by Dura, Polat, Berkers, Tineke, van Veen, Elke M, Salomon, Jody, te Morsche, Rene H M, Roelofs, Hennie M J, Kristinsson, Jon O, Wobbes, Theo, Witteman, Ben J M, Tan, Adriaan C I T L, Drenth, Joost P H, Peters, Wilbert H M

“…Esophageal cancer (EC), mainly consisting of squamous cell carcinoma (ESCC) in the Eastern world and adenocarcinoma (EAC) in the Western world, is strongly…”
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COX-2 polymorphisms -765G-->C and -1195A-->G and colorectal cancer risk by Hoff, Juliët H, te Morsche, Rene H M, Roelofs, Hennie M J, van der Logt, Elise M J, Nagengast, Fokko M, Peters, Wilbert H M

“…To determine the possible modulating effect of the COX-2 polymorphisms, -765G-->C and -1195A-->G, on the risk of colorectal cancer (CRC) in a Dutch population…”
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Oxidised- and total non-protein bound glutathione and related thiols in gallbladder bile of patients with various gastrointestinal disorders by Peters, Wilbert H M, van Schaik, Annie, Peters, Joost H, van Goor, Harry

“…Glutathione is a tripeptide composed of glutamate, cysteine and glycine, accomplishing a broad range of vital functions. Synthesis of glutathione and cysteine…”
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A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium by McKay, James D, Truong, Therese, Gaborieau, Valerie, Chabrier, Amelie, Chuang, Shu-Chun, Byrnes, Graham, Zaridze, David, Shangina, Oxana, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Bucur, Alexandru, Bencko, Vladimir, Holcatova, Ivana, Janout, Vladimir, Foretova, Lenka, Lagiou, Pagona, Trichopoulos, Dimitrios, Benhamou, Simone, Bouchardy, Christine, Ahrens, Wolfgang, Merletti, Franco, Richiardi, Lorenzo, Talamini, Renato, Barzan, Luigi, Kjaerheim, Kristina, Macfarlane, Gary J, Macfarlane, Tatiana V, Simonato, Lorenzo, Canova, Cristina, Agudo, Antonio, Castellsagué, Xavier, Lowry, Ray, Conway, David I, McKinney, Patricia A, Healy, Claire M, Toner, Mary E, Znaor, Ariana, Curado, Maria Paula, Koifman, Sergio, Menezes, Ana, Wünsch-Filho, Victor, Neto, José Eluf, Garrote, Leticia Fernández, Boccia, Stefania, Cadoni, Gabriella, Arzani, Dario, Olshan, Andrew F, Weissler, Mark C, Funkhouser, William K, Luo, Jingchun, Lubiński, Jan, Trubicka, Joanna, Lener, Marcin, Oszutowska, Dorota, Schwartz, Stephen M, Chen, Chu, Fish, Sherianne, Doody, David R, Muscat, Joshua E, Lazarus, Philip, Gallagher, Carla J, Chang, Shen-Chih, Zhang, Zuo-Feng, Wei, Qingyi, Sturgis, Erich M, Wang, Li-E, Franceschi, Silvia, Herrero, Rolando, Kelsey, Karl T, McClean, Michael D, Marsit, Carmen J, Nelson, Heather H, Romkes, Marjorie, Buch, Shama, Nukui, Tomoko, Zhong, Shilong, Lacko, Martin, Manni, Johannes J, Peters, Wilbert H M, Hung, Rayjean J, McLaughlin, John, Vatten, Lars, Njølstad, Inger, Goodman, Gary E, Field, John K, Liloglou, Triantafillos, Vineis, Paolo, Clavel-Chapelon, Francoise, Palli, Domenico, Tumino, Rosario, Krogh, Vittorio, Panico, Salvatore, González, Carlos A, Quirós, J Ramón, Martínez, Carmen, Navarro, Carmen, Ardanaz, Eva, Larrañaga, Nerea

“…Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex…”
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Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury by Ramakers, Bart P, Riksen, Niels P, van den Broek, Petra, Franke, Barbara, Peters, Wilbert H M, van der Hoeven, Johannes G, Smits, Paul, Pickkers, Peter

“…Preclinical studies have shown that the endogenous nucleoside adenosine prevents excessive tissue injury during systemic inflammation. We aimed to study…”
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Dipyridamole augments the antiinflammatory response during human endotoxemia by Ramakers, Bart P, Riksen, Niels P, Stal, Thijmen H, Heemskerk, Suzanne, van den Broek, Petra, Peters, Wilbert H M, van der Hoeven, Johannes G, Smits, Paul, Pickkers, Peter

“…In animal models of systemic inflammation, the endogenous nucleoside adenosine controls inflammation and prevents organ injury. Dipyridamole blocks the…”
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Disparities of conjugating protective enzyme activities in the colon of patients with adenomas and carcinomas by Hoensch, Harald P, Roelofs, Hennie M J, Edler, Lutz, Kirch, Wilhelm, Peters, Wilbert H M

“…To investigate the metabolic enzymatic capacity of the colon mucosa to detoxify noxious carcinogenic compounds. We investigated the activity of 2 conjugating…”
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Vascular and metabolic effects of the haem oxygenase-1 inducer haem arginate in subjects with the metabolic syndrome: A translational cross-over study by Dekker, Douwe, Dorresteijn, Mirrin J, Peters, Wilbert Hm, Bilos, Albert, Pennings, Sebastiaan W C, Wagener, Frank A D T G, Smits, Paul

“…This translational randomized and vehicle-controlled cross-over study was performed to assess the impact of haem arginate treatment on haem oxygenase-1…”
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Influence of Curcumin, Quercetin, and Eicosapentaenoic Acid on the Expression of Phase II Detoxification Enzymes in the Intestinal Cell Lines HT-29, Caco-2, HuTu 80, and LT97 by Odenthal, Julia, van Heumen, Bjorn W. H, Roelofs, Hennie M. J, te Morsche, Rene H. M, Marian, Brigitte, Nagengast, Fokko M, Peters, Wilbert H. M

“…Curcumin, quercetin, and eicosapentaenoic acid (EPA) are 3 natural compounds with the capacity to reduce adenoma burden in patients with familial adenomatous…”
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Celecoxib and tauro-ursodeoxycholic acid co-treatment inhibits cell growth in familial adenomatous polyposis derived LT97 colon adenoma cells by van Heumen, Bjorn W.H., Roelofs, Hennie M.J., te Morsche, René H.M., Marian, Brigitte, Nagengast, Fokko M., Peters, Wilbert H.M.

“…Chemoprevention would be a desirable strategy to avoid duodenectomy in patients with familial adenomatous polyposis (FAP) suffering from duodenal adenomatosis…”
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Allopurinol and 5-aminosalicylic acid influence thiopurine-induced hepatotoxicity in vitro by Broekman, Mark M. T. J., Roelofs, Hennie M. J., Wong, Dennis R., Kerstholt, Mariska, Leijten, Alex, Hoentjen, Frank, Peters, Wilbert H. M., Wanten, Geert J. A., de Jong, Dirk J.

“…Introduction The use of thiopurines is frequently accompanied by hepatotoxicity. Studies on hepatocyte cultures showed a time- and dose-dependent increase of…”
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Ursodeoxycholic acid counteracts celecoxib in reduction of duodenal polyps in patients with familial adenomatous polyposis: a multicentre, randomized controlled trial by van Heumen, Bjorn W H, Roelofs, Hennie M J, Vink-Börger, M Elisa, Dekker, Evelien, Mathus-Vliegen, Elisabeth M H, Dees, Jan, Koornstra, Jan J, Langers, Alexandra M J, Nagtegaal, Iris D, Kampman, Ellen, Peters, Wilbert H M, Nagengast, Fokko M

“…Due to prophylactic colectomy, mortality in patients with familial adenomatous polyposis (FAP) has changed, with duodenal cancer currently being the main cause…”
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Isoniazid and its toxic metabolite hydrazine induce in vitro pyrazinamide toxicity by Tostmann, Alma, Boeree, Martin J, Peters, Wilbert H.M, Roelofs, Hennie M.J, Aarnoutse, Rob E, van der Ven, André J.A.M, Dekhuijzen, P.N. Richard

“…Abstract Antituberculosis drug-induced hepatotoxicity (ATDH) complicates the treatment of 5–10% of patients treated for active tuberculosis (TB). Knowledge…”
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Infliximab Exerts No Direct Hepatotoxic Effect on HepG2 Cells In Vitro by de Vries, Hilbert S., de Heij, Tineke, Roelofs, Henie M. J., te Morsche, Rene H. M., Peters, Wilbert H. M., de Jong, Dirk J.

“…Background Infliximab-induced hepatotoxicity is reported in several case studies involving patients with inflammatory bowel disease (IBD) and a direct…”
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Assessment of plasma aminothiol levels and the association with recurrent atherothrombotic events in patients hospitalized for an acute coronary syndrome: a prospective study by Focks, Jeroen Jaspers, van Schaik, Annie, Clappers, Nick, van Dijk, Eveline G J A, van Oijen, Martijn G H, Verheugt, Freek W A, Peters, Wilbert H M

“…The aminothiols homocysteine and, to a lesser extent, cysteine have been associated with adverse cardiovascular outcome, whereas glutathione, as an…”
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Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls by van Heumen, Bjorn W H, Roelofs, Hennie M J, te Morsche, René H M, Nagengast, Fokko M, Peters, Wilbert H M

“…Familial adenomatous polyposis (FAP) is a disease characterized by the development of hundreds to thousands of adenomatous polyps in the colorectum early in…”
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