Search Results - "Peters, Reuben J."
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1
Two rings in them all: the labdane-related diterpenoids
Published in Natural product reports (01-01-2010)Get more information
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To gibberellins and beyond! Surveying the evolution of (di)terpenoid metabolism
Published in Annual review of plant biology (01-01-2014)“…The diterpenoids are classically defined by their composition--four isoprenyl units (20 carbons)--and are generally derived from [E,E,E]-geranylgeranyl…”
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Doing the gene shuffle to close synteny: dynamic assembly of biosynthetic gene clusters
Published in The New phytologist (01-08-2020)“…This article is a Commentary on Liu et al. (2020), 227: 1109–1123…”
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Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza
Published in Molecular plant (06-06-2016)Get full text
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Terpenoid synthase structures: a so far incomplete view of complex catalysis
Published in Natural product reports (01-01-2012)“…The complexity of terpenoid natural products has drawn significant interest, particularly since their common (poly)isoprenyl origins were discovered. Notably,…”
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Full‐length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis
Published in The Plant journal : for cell and molecular biology (01-06-2015)“…Summary Danshen, Salvia miltiorrhiza Bunge, is one of the most widely used herbs in traditional Chinese medicine, wherein its rhizome/roots are particularly…”
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Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae
Published in Organic & biomolecular chemistry (28-11-2013)“…Miltiradiene (1) is the precursor of phenolic diterpenoids such as ferruginol (2), requiring aromatization and hydroxylation. While this has been attributed to…”
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Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza
Published in Nature communications (29-01-2021)“…Tanshinones are the bioactive nor -diterpenoid constituents of the Chinese medicinal herb Danshen ( Salvia miltiorrhiza ). These groups of chemicals have the…”
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Isoprenyl diphosphate synthases: the chain length determining step in terpene biosynthesis
Published in Planta (01-01-2019)“…The highly diverse structures of all terpenes are synthesized from the five carbon precursors dimethylallyl diphosphate and a varying number of isopentenyl…”
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Dissecting the labdane‐related diterpenoid biosynthetic gene clusters in rice reveals directional cross‐cluster phytotoxicity
Published in The New phytologist (01-01-2022)“…Summary Rice (Oryza sativa) is a staple food crop and serves as a model cereal plant. It contains two biosynthetic gene clusters (BGCs) for the production of…”
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Plant (di)terpenoid evolution: from pigments to hormones and beyond
Published in Natural product reports (22-02-2023)“…Covering: up to 2014-2022.Diterpenoid biosynthesis in plants builds on the necessary production of ( , , )-geranylgeranyl diphosphate (GGPP) for photosynthetic…”
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The Role of Momilactones in Rice Allelopathy
Published in Journal of chemical ecology (01-02-2013)“…Large field screening programs and laboratory experiments in many countries have indicated that rice is allelopathic and releases allelochemical(s) into its…”
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Uncovering the complex metabolic network underlying diterpenoid phytoalexin biosynthesis in rice and other cereal crop plants
Published in Phytochemistry (Oxford) (01-11-2006)“…Recent identification of the genes encoding diterpene synthases involved in rice phytoalexin biosynthesis has enabled insight into the evolution of the…”
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Investigation of terpene diversification across multiple sequenced plant genomes
Published in Proceedings of the National Academy of Sciences - PNAS (06-01-2015)“…Significance The terpenes are the largest class of plant natural products. This major class of compounds represents tremendous chemical diversity of which only…”
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Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis
Published in Nature communications (20-02-2020)“…Triptolide is a trace natural product of Tripterygium wilfordii . It has antitumor activities, particularly against pancreatic cancer cells. Identification of…”
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Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins
Published in The Plant journal : for cell and molecular biology (01-08-2014)“…A long‐standing goal in plant research is to optimize the protective function of biochemical agents that impede pest and pathogen attack. Nearly 40 years ago,…”
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CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts
Published in Proceedings of the National Academy of Sciences - PNAS (16-07-2013)“…Cytochrome P450 enzymes (CYPs) play major roles in generating highly functionalized terpenoids, but identifying the exact biotransformation step(s) catalyzed…”
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The Application of Synthetic Biology to Elucidation of Plant Mono-, Sesqui-, and Diterpenoid Metabolism
Published in Molecular plant (01-01-2015)“…Plants synthesize a huge variety of terpenoid natural products, including photosynthetic pigments, signaling molecules, and defensive substances. These are…”
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Investigating the Phylogenetic Range of Gibberellin Biosynthesis in Bacteria
Published in Molecular plant-microbe interactions (01-04-2017)“…Certain plant-associated microbes can produce gibberellin (GA) phytohormones, as first described for the rice fungal pathogen Gibberella fujikuroi and, more…”
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Interdependent evolution of biosynthetic gene clusters for momilactone production in rice
Published in The Plant cell (17-04-2021)“…Plants can contain biosynthetic gene clusters (BGCs) that nominally resemble those found in microbes. However, while horizontal gene transmission is often…”
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