Search Results - "Peters, Melinda M."

CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity by Rogers, Justin T, Morganti, Josh M, Bachstetter, Adam D, Hudson, Charles E, Peters, Melinda M, Grimmig, Bethany A, Weeber, Edwin J, Bickford, Paula C, Gemma, Carmelina

“…The protective/neurotoxic role of fractalkine (CX3CL1) and its receptor CX3C chemokine receptor 1 (CX3CR1) signaling in neurodegenerative disease is an…”
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Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration by Liu, Qiang, Trotter, Justin, Zhang, Juan, Peters, Melinda M, Cheng, Hua, Bao, Jianxin, Han, Xianlin, Weeber, Edwin J, Bu, Guojun

“…The vast majority of Alzheimer's disease (AD) cases are late onset with progressive synapse loss and neurodegeneration. Although the amyloid hypothesis has…”
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Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome by Daily, Jennifer L, Nash, Kevin, Jinwal, Umesh, Golde, Todd, Rogers, Justin, Peters, Melinda M, Burdine, Rebecca D, Dickey, Chad, Banko, Jessica L, Weeber, Edwin J

“…Angelman syndrome (AS), a genetic disorder occurring in approximately one in every 15,000 births, is characterized by severe mental retardation, seizures,…”
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Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome by Hethorn, Whitney R., Ciarlone, Stephanie L., Filonova, Irina, Rogers, Justin T., Aguirre, Daniela, Ramirez, Raquel A., Grieco, Joseph C., Peters, Melinda M., Gulick, Danielle, Anderson, Anne E., L. Banko, Jessica, Lussier, April L., Weeber, Edwin J.

“…The Reelin signaling pathway is implicated in processes controlling synaptic plasticity and hippocampus‐dependent learning and memory. A single direct in vivo…”
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Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse by Rogers, Justin T, Zhao, Lisa, Trotter, Justin H, Rusiana, Ian, Peters, Melinda M, Li, Qingyou, Donaldson, Erika, Banko, Jessica L, Keenoy, Kathleen E, Rebeck, G William, Hoe, Hyang-Sook, D’Arcangelo, Gabriella, Weeber, Edwin J

“…The lipoprotein receptor ligand Reelin is important for the processes of normal synaptic plasticity, dendritic morphogenesis, and learning and memory…”
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Activation of Exchange Protein Activated by Cyclic-AMP Enhances Long-Lasting Synaptic Potentiation in the Hippocampus by Gelinas, Jennifer N, Banko, Jessica L, Peters, Melinda M, Klann, Eric, Weeber, Edwin J, Nguyen, Peter V

“…cAMP is a critical second messenger implicated in synaptic plasticity and memory in the mammalian brain. Substantial evidence links increases in intracellular…”
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Altered hippocampus synaptic function in selenoprotein P deficient mice by Peters, Melinda M, Hill, Kristina E, Burk, Raymond F, Weeber, Edwin J

“…Selenium is an essential micronutrient that function through selenoproteins. Selenium deficiency results in lower concentrations of selenium and…”
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Improving Gene Therapy for Angelman Syndrome with Secreted Human UBE3A by Nenninger, Austin W., Willman, Matthew, Willman, Jonathan, Stewart, Emma, Mesidor, Philippe, Novoa, Michelle, Morrill, Nicole K, Alvarez, Luis, Joly-Amado, Aurélie, Peters, Melinda M., Gulick, Danielle, Nash, Kevin R.

“…The rare genetic neurodevelopmental disease Angelman syndrome (AS) is caused by the loss of function of UBE3A , a ubiquitin ligase. The disease results in a…”
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Generation of a Novel Rat Model of Angelman Syndrome with a Complete Ube3a Gene Deletion by Dodge, Andie, Peters, Melinda M., Greene, Hayden E., Dietrick, Clifton, Botelho, Robert, Chung, Diana, Willman, Jonathan, Nenninger, Austin W., Ciarlone, Stephanie, Kamath, Siddharth G., Houdek, Pavel, Sumová, Alena, Anderson, Anne E., Dindot, Scott V., Berg, Elizabeth L., O'Geen, Henriette, Segal, David J., Silverman, Jill L., Weeber, Edwin J., Nash, Kevin R.

“…Angelman syndrome (AS) is a rare genetic disorder characterized by severe intellectual disability, seizures, lack of speech, and ataxia. The gene responsible…”
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Selenoprotein P function in hippocampal physiology and Alzheimer's disease by Bellinger, Frederick P, Peters, Melinda M, Raman, Arjun V, Pitts, Matthew W, Takemoto, Andrea S, Bellinger, Miyoko T, Burk, Raymond F, Zarow, Chris, White, Lon R, Berry, Marla J, Weeber, Edwin J

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P2‐252: Selenoprotein P function in hippocampal physiology and Alzheimer's disease by Bellinger, Frederick P., Peters, Melinda M., Raman, Arjun V., Pitts, Matthew W., Takemoto, Andrea S., Bellinger, Miyoko T., Burk, Raymond F., Zarow, Chris, White, Lon R., Berry, Marla J., Weeber, Edwin J.

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