Search Results - "Peters, Mary Linton Bounetheau"
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Immunohistochemical and genetic profiles do not predict behavior of mixed hepatocellular intrahepatic cholangiocarcinoma
Published in Journal of clinical oncology (01-02-2023)“…516 Background: Combined hepatocellular intrahepatic cholangiocarcinoma (HCC CC) is a rare tumor defined by pathologic characteristics of both hepatocellular…”
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2
PD-L1 as a predictor of chemo-immunotherapy response in biliary tract cancers: A systematic review and meta-analysis
Published in Journal of clinical oncology (20-01-2024)“…541 Background: Advanced biliary tract cancers (BTCs) are rare and aggressive malignancies with limited treatment options. Recently, immune checkpoint…”
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3
Molecular profiling as a predictor of treatment response and survival in unresectable pancreatic ductal adenocarcinoma
Published in Journal of clinical oncology (01-06-2023)“…e16279 Background: To date, few targetable mutations have been found to enhance PDAC treatment. Next-generation sequencing (NGS) of somatic mutation profiles…”
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4
Association between somatic mutation pathways and treatment response in patients with biliary tract cancers (BTCs)
Published in Journal of clinical oncology (01-06-2024)“…e16196 Background: Comprehensive somatic genomic profiling has become the standard of care for patients with BTCs, serving to identify targetable mutations and…”
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Comparison of neoadjuvant treatment modalities for locally advanced intrahepatic cholangiocarcinoma
Published in Journal of clinical oncology (20-01-2024)“…510 Background: The only curative therapy available for intrahepatic cholangiocarcinoma (IHCC) is resection. Nonetheless, most patients (pts) are diagnosed at…”
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Cascade testing of first-degree relatives of patients with pancreatic cancer with confirmed germline genetic mutations: A simulation modeling study
Published in Journal of clinical oncology (01-06-2022)“…10513 Background: Universal germline genetic testing is recommended for all patients with pancreatic ductal adenocarcinoma (PDAC). In addition to treatment…”
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COVID-19 clearance among patients with cancer during the Delta and Omicron waves
Published in Journal of clinical oncology (01-10-2022)“…42 Background: COVID-19 presents a particular challenge in oncology, as in-person visits and treatments can be delayed during infection and patients are at…”
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Uptake in genetic testing in patients with pancreatic cancer with oncologist-driven testing protocol
Published in Journal of clinical oncology (01-10-2022)“…33 Background: The objective was to compare the uptake of genetic testing in patients with pancreatic adenocarcinoma (PDAC) seen at a single center (1) before…”
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9
Number of subsequent treatments and time to recurrence in hepatocellular carcinoma
Published in Journal of clinical oncology (20-01-2024)“…526 Background: Hepatocellular carcinoma (HCC) is often managed with locoregional therapies including surgical resection, ablation, transcatheter arterial…”
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10
Association of immune related adverse events with superior outcomes in patients with hepatocellular carcinoma (HCC) treated with nivolumab
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e16630 Background: Nivolumab, an anti-PD1 antibody, is FDA approved in patients (pts) with HCC. Anti-PD-1 promotes hyperstimulation of host…”
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11
Time to COVID-19 RT-PCR clearance among patients with cancer
Published in Journal of clinical oncology (10-10-2020)“…Abstract only 49 Background: COVID-19 in oncologic patients presents a clinical dilemma. To reduce the risk of adverse events as well as the risk of exposing…”
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12
GI oncology molecular tumor board: Fostering collaboration and clinical education for personalized therapy
Published in Journal of clinical oncology (20-05-2020)“…Abstract only 11029 Background: In recent years, genomic profiling has become standard of care for several gastrointestinal (GI) cancers. In addition to…”
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13
A phase I study of LY3410738, a first-in-class covalent inhibitor of mutant IDH1 in cholangiocarcinoma and other advanced solid tumors
Published in Journal of clinical oncology (20-01-2021)“…Abstract only TPS350 Background: Mutations in isocitrate dehydrogenase 1 (mIDH1) are found in approximately 20-30% of patients with intrahepatic…”
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Comparison of the clinical features, treatment patterns, and tumor mutations of patients with intrahepatic (ICC) and extrahepatic (ECC) cholangiocarcinoma
Published in Journal of clinical oncology (01-02-2020)“…Abstract only 580 Background: Though studies indicate that the genomic profiles of ICC and ECC are distinct, the clinical features that differentiate them…”
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15
Germline genetic testing in unselected pancreatic ductal adenocarcinoma (PDAC) patients
Published in Journal of clinical oncology (20-05-2017)“…Abstract only 1501 Background: The aim of this study is to assess the prevalence of known heritable germline mutations in unselected PDAC patients and to…”
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