Search Results - "Peters, G.P."

INPUT-OUTPUT ANALYSIS AND CARBON FOOTPRINTING: AN OVERVIEW OF APPLICATIONS by Minx, J.C., Wiedmann, T., Wood, R., Peters, G.P., Lenzen, M., Owen, A., Scott, K., Barrett, J., Hubacek, K., Baiocchi, G., Paul, A., Dawkins, E., Briggs, J., Guan, D., Suh, S., Ackerman, F.

“…This article provides an overview of how generalised multi-regional input-output models can be used for carbon footprint applications. We focus on the…”
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Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia by Vriend, Jelle, Peters, Janny G.P., Nieskens, Tom T.G., Škovroňová, Renata, Blaimschein, Nina, Schmidts, Miriam, Roepman, Ronald, Schirris, Tom J.J., Russel, Frans G.M., Masereeuw, Rosalinde, Wilmer, Martijn J.

“…Kidney disease modeling and assessment of drug-induced kidney injury can be advanced using three-dimensional (3D) microfluidic models that recapitulate in vivo…”
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Persistent fossil fuel growth threatens the Paris Agreement and planetary health by Jackson, R B, Friedlingstein, P, Andrew, R M, Canadell, J G, Le Quéré, C, Peters, G P

“…Amidst declarations of planetary emergency and reports that the window for limiting climate change to 1.5 °C is rapidly closing, global average temperatures…”
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Characterization of P-glycoprotein and multidrug resistance proteins in rat kidney and intestinal cell lines by van de Water, Femke M., Boleij, Johanna M., Peters, Janny G.P., Russel, Frans G.M., Masereeuw, Rosalinde

“…The activity of P-glycoprotein (Pgp/MDR1/ABCB1) and multidrug resistance proteins (MRP/ABCC) influence the pharmacokinetics and bioavailability of many drugs…”
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Perspective of comprehensive and comprehensible multi-model energy and climate science in Europe by Nikas, A., Gambhir, A., Trutnevyte, E., Koasidis, K., Lund, H., Thellufsen, J.Z., Mayer, D., Zachmann, G., Miguel, L.J., Ferreras-Alonso, N., Sognnaes, I., Peters, G.P., Colombo, E., Howells, M., Hawkes, A., van den Broek, M., Van de Ven, D.J., Gonzalez-Eguino, M., Flamos, A., Doukas, H.

“…Europe’s capacity to explore the envisaged pathways that achieve its near- and long-term energy and climate objectives needs to be significantly enhanced. In…”
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Research priorities for negative emissions by Fuss, S, Jones, C D, Kraxner, F, Peters, G P, Smith, P, Tavoni, M, van Vuuren, D P, Canadell, J G, Jackson, R B, Milne, J, Moreira, J R, Nakicenovic, N, Sharifi, A, Yamagata, Y

“…Carbon dioxide removal from the atmosphere (CDR)-also known as 'negative emissions'-features prominently in most 2 °C scenarios and has been under increased…”
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Global Carbon Budget 2015 by Le Quéré, C, Moriarty, R, Andrew, R. M, Canadell, J. G, Sitch, S, Korsbakken, J. I, Friedlingstein, P, Peters, G. P, Andres, R. J, Boden, T. A, Houghton, R. A, House, J. I, Keeling, R. F, Tans, P, Arneth, A, Bakker, D. C. E, Barbero, L, Bopp, L, Chang, J, Chevallier, F, Chini, L. P, Ciais, P, Fader, M, Feely, R. A, Gkritzalis, T, Harris, I, Hauck, J, Ilyina, T, Jain, A. K, Kato, E, Kitidis, V, Klein Goldewijk, K, Koven, C, Landschützer, P, Lauvset, S. K, Lefèvre, N, Lenton, A, Lima, I. D, Metzl, N, Millero, F, Munro, D. R, Murata, A, Nabel, J. E. M. S, Nakaoka, S, Nojiri, Y, O'Brien, K, Olsen, A, Ono, T, Pérez, F. F, Pfeil, B, Pierrot, D, Poulter, B, Rehder, G, Rödenbeck, C, Saito, S, Schuster, U, Schwinger, J, Séférian, R, Steinhoff, T, Stocker, B. D, Sutton, A. J, Takahashi, T, Tilbrook, B, van der Laan-Luijkx, I. T, van der Werf, G. R, van Heuven, S, Vandemark, D, Viovy, N, Wiltshire, A, Zaehle, S, Zeng, N

“…Accurate assessment of anthropogenic carbon dioxide (CO2) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere is…”
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Simulating the Earth system response to negative emissions by Jones, C D, Ciais, P, Davis, S J, Friedlingstein, P, Gasser, T, Peters, G P, Rogelj, J, van Vuuren, D P, Canadell, J G, Cowie, A, Jackson, R B, Jonas, M, Kriegler, E, Littleton, E, Lowe, J A, Milne, J, Shrestha, G, Smith, P, Torvanger, A, Wiltshire, A

“…Natural carbon sinks currently absorb approximately half of the anthropogenic CO2 emitted by fossil fuel burning, cement production and land-use change…”
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A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity by Nieskens, Tom T. G., Peters, Janny G. P., Schreurs, Marieke J., Smits, Niels, Woestenenk, Rob, Jansen, Katja, van der Made, Thom K., Röring, Melanie, Hilgendorf, Constanze, Wilmer, Martijn J, Masereeuw, Rosalinde

“…Drug-induced nephrotoxicity still hampers drug development, because current translation from in vitro or animal studies to human lacks high predictivity…”
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INTRAVENOUSLY ADMINISTERED SHORT INTERFERING RNA ACCUMULATES IN THE KIDNEY AND SELECTIVELY SUPPRESSES GENE FUNCTION IN RENAL PROXIMAL TUBULES by VAN DE WATER, Femke M, BOERMAN, Otto C, WOUTERSE, Alfons C, PETERS, Janny G. P, RUSSEL, Frans G. M, MASEREEUW, Rosalinde

“…Different gene-silencing methods, like antisense and short interfering RNA (siRNA), are widely used as experimental tools to inhibit gene expression. In the…”
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The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: Putative efflux pump for urinary cAMP and cGMP by VAN AUBEL, Rémon A. M. H, SMEETS, Pascal H. E, PETERS, Janny G. P, BINDELS, René J. M, RUSSEL, Frans G. M

“…The cyclic nucleotides cAMP and cGMP play key roles in cellular signaling and the extracellular regulation of fluid balance. In the kidney, cAMP is excreted…”
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Subunit-specific Incorporation Efficiency and Kinetics in Mitochondrial Complex I Homeostasis by Dieteren, Cindy E.J., Koopman, Werner J.H., Swarts, Herman G., Peters, Janny G.P., Maczuga, Piotr, van Gemst, Jasper J., Masereeuw, Rosalinde, Smeitink, Jan A.M., Nijtmans, Leo G.J., Willems, Peter H.G.M.

“…Studies employing native PAGE suggest that most nDNA-encoded CI subunits form subassemblies before assembling into holo-CI. In addition, in vitro evidence…”
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Humoral signalling compounds in remote ischaemic preconditioning of the kidney, a role for the opioid receptor by Wever, Kimberley E, Masereeuw, Rosalinde, Wagener, Frank A, Verweij, Vivienne G M, Peters, Janny G P, Pertijs, Jeanne C L M, Van der Vliet, J Adam, Warlé, Michiel C, Rongen, Gerard A

“…Renal ischaemia-reperfusion injury (IRI) is a common clinical problem associated with significant mortality and morbidity. One strategy to reduce this damage…”
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Acute acetaminophen intoxication leads to hepatic iron loading by decreased hepcidin synthesis by van Swelm, Rachel P L, Laarakkers, Coby M M, Blous, Linda, Peters, Janny G P, Blaney Davidson, Esmeralda N, van der Kraan, Peter M, Swinkels, Dorine W, Masereeuw, Rosalinde, Russel, Frans G M

“…Acetaminophen (APAP), a major cause of acute liver injury in the Western world, is mediated by metabolism and oxidative stress. Recent studies have suggested a…”
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Can sulfasalazine therapy induce or exacerbate Wegener's granulomatosis? by Denissen, N. H. A. M., Peters, J. G. P., Masereeuw, R., Barrera, P.

“…Sulfasalazine (SSZ) can induce serological and clinical autoimmune reactions but the occurrence of SSZ-related Wegener's granulomatosis (WG) has not been…”
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Mechanisms and interaction of vinblastine and reduced glutathione transport in membrane vesicles by the rabbit multidrug resistance protein Mrp2 expressed in insect cells by Van Aubel, R A, Koenderink, J B, Peters, J G, Van Os, C H, Russel, F G

“…The present study examined how the multidrug resistance protein (MRP) 2, which is an ATP-dependent anionic conjugate transporter, also mediates transport of…”
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Multidrug resistance protein mrp2 mediates ATP-dependent transport of classic renal organic anion p-aminohippurate by Van Aubel, R A, Peters, J G, Masereeuw, R, Van Os, C H, Russel, F G

“…p-Aminohippurate (PAH) is widely used as a model substrate to characterize organic anion transport in kidney proximal tubules. The carrier responsible for…”
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Quinone toxicity in DT-diaphorase-efficient and -deficient colon carcinoma cell lines by Karczewski, Jurgen M., Peters, Janny G.P., Noordhoek, Jan

“…The human colon carcinoma cell lines Caco-2 and HT-29 were exposed to three structurally related naphthoquinones. Menadione (MEN), 1,4-naphthoquinone (NQ), and…”
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Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca 2+ chelation: involvement of a common mechanism by Karczewski, Jurgen M., Peters, Janny G.P., Noordhoek, Jan

“…The human colon carcinoma cell line Caco-2 was exposed to the oxidative stress-inducing agents menadione (MEN), 2,3-dimethoxy-1,4-naphthoquinone, and hydrogen…”
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Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation : Involvement of a common mechanism by KARCZEWSKI, J. M, PETERS, J. G. P, NOORDHOEK, J

“…The human colon carcinoma cell line Caco-2 was exposed to the oxidative stress-inducing agents menadione (MEN), 2,3-dimethoxy-1,4-naphthoquinone, and hydrogen…”
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