Search Results - "Peterlin, Zita"
-
1
Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2013)“…Olfactory receptors are G protein-coupled receptors that mediate olfactory chemosensation and serve as chemosensors in other tissues. We find that Olfr78, an…”
Get full text
Journal Article -
2
The state of the art of odorant receptor deorphanization: a report from the orphanage
Published in The Journal of general physiology (01-05-2014)“…The odorant receptors (ORs) provide our main gateway to sensing the world of volatile chemicals. This involves a complex encoding process in which multiple…”
Get full text
Journal Article -
3
Odorant Receptor Inhibition Is Fundamental to Odor Encoding
Published in Current biology (06-07-2020)“…Most natural odors are complex mixtures of volatile components, competing to bind odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs) of the…”
Get full text
Journal Article -
4
A Renal Olfactory Receptor Aids in Kidney Glucose Handling
Published in Scientific reports (14-10-2016)“…Olfactory receptors (ORs) are G protein-coupled receptors which serve important sensory functions beyond their role as odorant detectors in the olfactory…”
Get full text
Journal Article -
5
Applying medicinal chemistry strategies to understand odorant discrimination
Published in Nature communications (04-04-2016)“…Associating an odorant’s chemical structure with its percept is a long-standing challenge. One hindrance may come from the adoption of the organic chemistry…”
Get full text
Journal Article -
6
G protein/cAMP signal cascade is required for axonal convergence into olfactory glomeruli
Published in Proceedings of the National Academy of Sciences - PNAS (16-01-2007)“…The mammalian odorant receptors (ORs) comprise a large family of G protein-coupled receptors that are critical determinants of both the odorant response…”
Get full text
Journal Article -
7
A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium
Published in The Journal of physiology (16-03-2004)“…Several lines of evidence suggest that odorants are recognized through a combinatorial process in the olfactory system; a single odorant is recognized by…”
Get full text
Journal Article -
8
Detection of explosives by olfactory sensory neurons
Published in Journal of hazardous materials (15-03-2010)“…The response of olfactory sensory neurons to TNT and RDX as well as to some volatile organic compounds present in the vapors of antipersonnel landmines has…”
Get full text
Journal Article -
9
Quantitative morphologic classification of layer 5 neurons from mouse primary visual cortex
Published in Journal of comparative neurology (1911) (07-07-2003)“…The understanding of any neural circuit requires the identification and characterization of all its components. Morphologic classifications of neurons are,…”
Get full text
Journal Article -
10
Optical Probing of Neuronal Circuits with Calcium Indicators
Published in Proceedings of the National Academy of Sciences - PNAS (28-03-2000)“…An experimental difficulty in unraveling circuits in the mammalian nervous system is the identification of postsynaptic targets of a given neuron. Besides…”
Get full text
Journal Article -
11
Involvement of Cajal-Retzius Neurons in Spontaneous Correlated Activity of Embryonic and Postnatal Layer 1 from Wild-Type and Reeler Mice
Published in The Journal of neuroscience (15-12-1999)“…Cajal-Retzius (CR) cells are a transient population of neurons in developing cortical layer 1 that secrete reelin, a protein necessary for cortical lamination…”
Get full text
Journal Article -
12
Olfactory receptor responding to gut microbiotaderived signals plays a role in renin secretion and blood pressure regulation
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2013)“…Olfactory receptors are G protein-coupled receptors that mediate olfactory chemosensation and serve as chemosensors in other tissues. We find that Olfr78, an…”
Get full text
Journal Article -
13
Deorphanizing Renal Olfactory Receptor 1393
Published in The FASEB journal (01-04-2016)“…Abstract only Olfactory receptors (ORs) are G protein‐coupled receptors which serve to detect odorants in the nose. Recently, ORs have been shown to play novel…”
Get full text
Journal Article -
14
Functional odor classification through a medicinal chemistry approach
Published in Science advances (01-02-2018)“…Crucial for any hypothesis about odor coding is the classification and prediction of sensory qualities in chemical compounds. The relationship between…”
Get full text
Journal Article -
15
The Importance of Odorant Conformation to the Binding and Activation of a Representative Olfactory Receptor
Published in Chemistry & biology (22-12-2008)“…Olfactory receptors (ORs) form a large family of G protein-coupled receptor proteins (GPCRs) responsible for sensing the ambient chemical environment. The…”
Get full text
Journal Article -
16
A Painful Trp Can Be a Bonding Experience
Published in Neuron (Cambridge, Mass.) (01-03-2007)“…The receptive field of the TRPA1 nociceptor is remarkably expansive when compared to other chemodetectors such as odorant receptors. The identification of a…”
Get full text
Journal Article -
17
A Renal Olfactory Receptor Aids in Kidney Glucose Handling
Published in Scientific reports (01-12-2016)“…Olfactory receptors (ORs) are G protein-coupled receptors which serve important sensory functions beyond their role as odorant detectors in the olfactory…”
Get full text
Journal Article -
18
Aldehyde Recognition and Discrimination by Mammalian Odorant Receptors via Functional Group-Specific Hydration Chemistry
Published in ACS chemical biology (21-11-2014)“…The mammalian odorant receptors (ORs) form a chemical-detecting interface between the atmosphere and the nervous system. This large gene family is composed of…”
Get full text
Journal Article -
19
Pharmacology of mammalian olfactory receptors
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…Mammalian species have evolved a large and diverse number of odorant receptors (ORs). These proteins comprise the largest family of G-protein-coupled receptors…”
Get more information
Journal Article -
20
Discrimination of Saturated Aldehydes by the Rat I7 Olfactory Receptor
Published in Biochemistry (Easton) (03-08-2010)“…The discrimination of n-alkyl-saturated aldehydes during the early stage of odorant recognition by the rat I7 olfactory receptor (OR-I7) is investigated. The…”
Get full text
Journal Article