Search Results - "Peterlin, Zita"

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    The state of the art of odorant receptor deorphanization: a report from the orphanage by Peterlin, Zita, Firestein, Stuart, Rogers, Matthew E

    Published in The Journal of general physiology (01-05-2014)
    “…The odorant receptors (ORs) provide our main gateway to sensing the world of volatile chemicals. This involves a complex encoding process in which multiple…”
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    Odorant Receptor Inhibition Is Fundamental to Odor Encoding by Pfister, Patrick, Smith, Benjamin C., Evans, Barry J., Brann, Jessica H., Trimmer, Casey, Sheikh, Mushhood, Arroyave, Randy, Reddy, Gautam, Jeong, Hyo-Young, Raps, Daniel A., Peterlin, Zita, Vergassola, Massimo, Rogers, Matthew E.

    Published in Current biology (06-07-2020)
    “…Most natural odors are complex mixtures of volatile components, competing to bind odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs) of the…”
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    A Renal Olfactory Receptor Aids in Kidney Glucose Handling by Shepard, Blythe D., Cheval, Lydie, Peterlin, Zita, Firestein, Stuart, Koepsell, Hermann, Doucet, Alain, Pluznick, Jennifer L.

    Published in Scientific reports (14-10-2016)
    “…Olfactory receptors (ORs) are G protein-coupled receptors which serve important sensory functions beyond their role as odorant detectors in the olfactory…”
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    Applying medicinal chemistry strategies to understand odorant discrimination by Poivet, Erwan, Peterlin, Zita, Tahirova, Narmin, Xu, Lu, Altomare, Clara, Paria, Anne, Zou, Dong-Jing, Firestein, Stuart

    Published in Nature communications (04-04-2016)
    “…Associating an odorant’s chemical structure with its percept is a long-standing challenge. One hindrance may come from the adoption of the organic chemistry…”
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    G protein/cAMP signal cascade is required for axonal convergence into olfactory glomeruli by Chesler, Alexander T, Zou, Dong-Jing, Le Pichon, Claire E, Peterlin, Zita A, Matthews, Glennis A, Pei, Xin, Miller, Michael C, Firestein, Stuart

    “…The mammalian odorant receptors (ORs) comprise a large family of G protein-coupled receptors that are critical determinants of both the odorant response…”
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    A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium by Araneda, Ricardo C., Peterlin, Zita, Zhang, Xinmin, Chesler, Alex, Firestein, Stuart

    Published in The Journal of physiology (16-03-2004)
    “…Several lines of evidence suggest that odorants are recognized through a combinatorial process in the olfactory system; a single odorant is recognized by…”
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    Detection of explosives by olfactory sensory neurons by Corcelli, Angela, Lobasso, Simona, Lopalco, Patrizia, Dibattista, Michele, Araneda, Ricardo, Peterlin, Zita, Firestein, Stuart

    Published in Journal of hazardous materials (15-03-2010)
    “…The response of olfactory sensory neurons to TNT and RDX as well as to some volatile organic compounds present in the vapors of antipersonnel landmines has…”
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    Quantitative morphologic classification of layer 5 neurons from mouse primary visual cortex by Tsiola, Areti, Hamzei-Sichani, Farid, Peterlin, Zita, Yuste, Rafael

    Published in Journal of comparative neurology (1911) (07-07-2003)
    “…The understanding of any neural circuit requires the identification and characterization of all its components. Morphologic classifications of neurons are,…”
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    Optical Probing of Neuronal Circuits with Calcium Indicators by Peterlin, Zita A., Kozloski, James, Mao, Bu-Qing, Tsiola, Areti, Yuste, Rafael

    “…An experimental difficulty in unraveling circuits in the mammalian nervous system is the identification of postsynaptic targets of a given neuron. Besides…”
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    Involvement of Cajal-Retzius Neurons in Spontaneous Correlated Activity of Embryonic and Postnatal Layer 1 from Wild-Type and Reeler Mice by Aguilo, Agusti, Schwartz, Theodore H, Kumar, Vikram S, Peterlin, Zita A, Tsiola, Areti, Soriano, Eduardo, Yuste, Rafael

    Published in The Journal of neuroscience (15-12-1999)
    “…Cajal-Retzius (CR) cells are a transient population of neurons in developing cortical layer 1 that secrete reelin, a protein necessary for cortical lamination…”
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    Deorphanizing Renal Olfactory Receptor 1393 by Shepard, Blythe D, Peterlin, Zita, Firestein, Stuart, Pluznick, Jennifer L

    Published in The FASEB journal (01-04-2016)
    “…Abstract only Olfactory receptors (ORs) are G protein‐coupled receptors which serve to detect odorants in the nose. Recently, ORs have been shown to play novel…”
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    Functional odor classification through a medicinal chemistry approach by Poivet, Erwan, Tahirova, Narmin, Peterlin, Zita, Xu, Lu, Zou, Dong-Jing, Acree, Terry, Firestein, Stuart

    Published in Science advances (01-02-2018)
    “…Crucial for any hypothesis about odor coding is the classification and prediction of sensory qualities in chemical compounds. The relationship between…”
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    The Importance of Odorant Conformation to the Binding and Activation of a Representative Olfactory Receptor by Peterlin, Zita, Li, Yadi, Sun, Guangxing, Shah, Rohan, Firestein, Stuart, Ryan, Kevin

    Published in Chemistry & biology (22-12-2008)
    “…Olfactory receptors (ORs) form a large family of G protein-coupled receptor proteins (GPCRs) responsible for sensing the ambient chemical environment. The…”
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    A Painful Trp Can Be a Bonding Experience by Peterlin, Zita, Chesler, Alexander, Firestein, Stuart

    Published in Neuron (Cambridge, Mass.) (01-03-2007)
    “…The receptive field of the TRPA1 nociceptor is remarkably expansive when compared to other chemodetectors such as odorant receptors. The identification of a…”
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    A Renal Olfactory Receptor Aids in Kidney Glucose Handling by Shepard, Blythe, Cheval, Lydie L, Peterlin, Zita D, Firestein, Stuart D, Koepsell, Hermann D, Doucet, Alain L, Pluznick, Jennifer

    Published in Scientific reports (01-12-2016)
    “…Olfactory receptors (ORs) are G protein-coupled receptors which serve important sensory functions beyond their role as odorant detectors in the olfactory…”
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    Journal Article
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    Aldehyde Recognition and Discrimination by Mammalian Odorant Receptors via Functional Group-Specific Hydration Chemistry by Li, Yadi, Peterlin, Zita, Ho, Jianghai, Yarnitzky, Tali, Liu, Min Ting, Fichman, Merav, Niv, Masha Y., Matsunami, Hiroaki, Firestein, Stuart, Ryan, Kevin

    Published in ACS chemical biology (21-11-2014)
    “…The mammalian odorant receptors (ORs) form a chemical-detecting interface between the atmosphere and the nervous system. This large gene family is composed of…”
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    Pharmacology of mammalian olfactory receptors by Smith, Richard S, Peterlin, Zita, Araneda, Ricardo C

    “…Mammalian species have evolved a large and diverse number of odorant receptors (ORs). These proteins comprise the largest family of G-protein-coupled receptors…”
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    Discrimination of Saturated Aldehydes by the Rat I7 Olfactory Receptor by Kurland, Michael D, Newcomer, Michael B, Peterlin, Zita, Ryan, Kevin, Firestein, Stuart, Batista, Victor S

    Published in Biochemistry (Easton) (03-08-2010)
    “…The discrimination of n-alkyl-saturated aldehydes during the early stage of odorant recognition by the rat I7 olfactory receptor (OR-I7) is investigated. The…”
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