Search Results - "Peter Whitney"
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The method in the madness: Transcriptional control from stochastic action at the single-molecule scale
Published in Current opinion in structural biology (01-08-2024)“…Cell states result from the ordered activation of gene expression by transcription factors. Transcription factors face opposing design constraints: they need…”
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Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators
Published in Development (Cambridge) (15-02-2016)“…Nephron endowment is determined by the self-renewal and induction of a nephron progenitor pool established at the onset of kidney development. In the mouse,…”
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3
Spatial organization of transcribing loci during early genome activation in Drosophila
Published in Current biology (22-11-2021)“…The early Drosophila embryo provides unique experimental advantages for addressing fundamental questions of gene regulation at multiple levels of organization,…”
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4
The Drosophila Pioneer Factor Zelda Modulates the Nuclear Microenvironment of a Dorsal Target Enhancer to Potentiate Transcriptional Output
Published in Current biology (22-04-2019)“…Connecting the developmental patterning of tissues to the mechanistic control of RNA polymerase II remains a long-term goal of developmental biology. Many key…”
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5
Shadow enhancers modulate distinct transcriptional parameters that differentially effect downstream patterning events
Published in Development (Cambridge) (01-11-2022)“…Transcription in the early Drosophila blastoderm is coordinated by the collective action of hundreds of enhancers. Many genes are controlled by so-called…”
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6
Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment
Published in eLife (05-12-2018)“…A normal endowment of nephrons in the mammalian kidney requires a balance of nephron progenitor self-renewal and differentiation throughout development. Here,…”
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7
Analysis and Perspectives on the ANA Avatar XPRIZE Competition
Published in International journal of social robotics (30-01-2024)“…The ANA Avatar XPRIZE was a four-year competition to develop a robotic “avatar” system to allow a human operator to sense, communicate, and act in a remote…”
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8
Exploring the Impacts of Protected Areas’ Attributes on Pediatric Health: The Case for Additional Research beyond Greenspace
Published in Land (Basel) (01-08-2023)“…An increasingly vast segment of the literature examines the relationship between greenspace and pediatric health. However, the bulk of this research continues…”
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9
Genome Sequencing Variations in the Octodon degus , an Unconventional Natural Model of Aging and Alzheimer's Disease
Published in Frontiers in aging neuroscience (30-06-2022)“…The degu ( ) is a diurnal long-lived rodent that can spontaneously develop molecular and behavioral changes that mirror those seen in human aging. With age…”
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10
The modern paediatric injury pyramid: injuries in Massachusetts children and adolescents
Published in Injury prevention (01-04-2010)“…The objective of this study was to develop a modern version of the paediatric injury pyramid, a visual classification of injury severity, and to present…”
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11
Postnatal development of cholinergic input to the thalamic reticular nucleus of the mouse
Published in The European journal of neuroscience (01-04-2019)“…The thalamic reticular nucleus (TRN), a shell‐like structure comprised of GABAergic neurons, gates signal transmission between thalamus and cortex. While TRN…”
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12
Using Systemised Nomenclature of Medicine (SNOMED) codes to select digital pathology whole slide images for long-term archiving
Published in Journal of clinical pathology (01-05-2023)“…The archiving of whole slide images represents a hurdle to digital pathology implementation largely because of the amount of data generated. The retention of…”
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13
Linewidth considerations for MEMS tunable VCSEL LiDAR
Published in Optics express (09-05-2022)“…The flexible membranes used in MEMS tunable VCSELs are so small and light that thermally induced vibrations can impact laser performance. We measure the…”
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14
Long-to-short wavelength swept source
Published in Optics express (24-12-2018)“…Most swept external cavity diode lasers tune in the short-to-long wavelength direction (red tuning). Lower relative intensity noise (RIN) and higher output…”
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15
LA PROTECCION DE LOS DERECHOS INTELECTUALES Y DEL MEDIO AMBIENTE EN EL ACUERDO DE LIBRE COMERCIO ENTRE LOS ESTADOS UNIDOS, CANADA Y MEXICO (NAFTA)
Published in Relaciones internacionales (La Plata, Argentina) (01-12-2018)“…En español El Consejero para Asuntos Económicos de la Embajada de los Estados Unidos analiza brevemente los principales objetivos del Acuerdo de Libre Comercio…”
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16
Developments in big data for park management: a review of mobile phone location data for visitor use management
Published in Landscape research (18-08-2023)“…Land managers and public agencies strive to manage parks and protected areas (PPAs) for a balance between the preservation of ecological health and the visitor…”
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17
Principles of Enhancer Biology in the Developing Drosophila Embryo
Published 01-01-2022“…The regulation of transcription underlies most major cellular processes. In order for a cell to have the appropriate set of proteins to perform biological…”
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Dissertation -
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Exclusionary Effects of Campsite Allocation through Reservations in U.S. National Parks: Evidence from Mobile Device Location Data
Published in Journal of park and recreation administration (24-10-2022)“…Campsites represent highly-sought-after recreational amenities in the national parks of the United States. Equitable allocation of scarce recreational…”
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19
SNR of swept SLEDs and swept lasers for OCT
Published in Optics express (16-05-2016)“…A back-to-back comparison of a tunable narrow-band-filtered SLED (TSLED) and a swept laser are made for OCT applications. The two sources are similar in terms…”
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20
Coherence properties of short cavity swept lasers
Published in Biomedical optics express (01-02-2017)“…It has been shown theoretically and experimentally that short cavity swept lasers are passively mode locked. We develop a mathematical model of these lasers…”
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