Search Results - "Peter M. G. Munro"

Regulation of cell protrusions by small GTPases during fusion of the neural folds by Rolo, Ana, Savery, Dawn, Escuin, Sarah, de Castro, Sandra C, Armer, Hannah E J, Munro, Peter M G, Molè, Matteo A, Greene, Nicholas D E, Copp, Andrew J

“…Epithelial fusion is a crucial process in embryonic development, and its failure underlies several clinically important birth defects. For example, failure of…”
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The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice by Georgiadis, Anastasios, Tschernutter, Marion, Bainbridge, James W B, Balaggan, Kamaljit S, Mowat, Freya, West, Emma L, Munro, Peter M G, Thrasher, Adrian J, Matter, Karl, Balda, Maria S, Ali, Robin R

“…Cell-cell adhesion regulates the development and function of epithelia by providing mechanical support and by guiding cell proliferation and differentiation…”
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The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation by Saliba, Richard S, Munro, Peter M G, Luthert, Philip J, Cheetham, Michael E

“…Mutations in the photopigment rhodopsin are the major cause of autosomal dominant retinitis pigmentosa. The majority of mutations in rhodopsin lead to…”
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Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling by Luhmann, Ulrich F O, Lange, Clemens A, Robbie, Scott, Munro, Peter M G, Cowing, Jill A, Armer, Hannah E J, Luong, Vy, Carvalho, Livia S, MacLaren, Robert E, Fitzke, Frederick W, Bainbridge, James W B, Ali, Robin R

“…Microglia and macrophages are recruited to sites of retinal degeneration where local cytokines and chemokines determine protective or neurotoxic microglia…”
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Correction: The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice by Georgiadis, Anastasios, Tschernutter, Marion, Bainbridge, James W B, Balaggan, Kamaljit S, Mowat, Freya, West, Emma L, Munro, Peter M G, Thrasher, Adrian J, Matter, Karl, Balda, Maria S, Ali, Robin R

“…[This corrects the article DOI: 10.1371/journal.pone.0015730.]…”
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The Drusenlike Phenotype in Aging Ccl2-Knockout Mice Is Caused by an Accelerated Accumulation of Swollen Autofluorescent Subretinal Macrophages by Luhmann, Ulrich F. O, Robbie, Scott, Munro, Peter M. G, Barker, Susie E, Duran, Yanai, Luong, Vy, Fitzke, Frederick W, Bainbridge, James W. B, Ali, Robin R, MacLaren, Robert E

“…Drusen, which are defined clinically as yellowish white spots in the outer retina, are cardinal features of age-related macular degeneration (AMD)…”
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Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation by Zihni, Ceniz, Munro, Peter M G, Elbediwy, Ahmed, Keep, Nicholas H, Terry, Stephen J, Harris, John, Balda, Maria S, Matter, Karl

“…Epithelial cells develop morphologically characteristic apical domains that are bordered by tight junctions, the apical-lateral border. Cdc42 and its effector…”
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Autologous Transplantation of the Retinal Pigment Epithelium and Choroid in the Treatment of Neovascular Age-Related Macular Degeneration by MacLaren, Robert E., DPhil, FRCOphth, Uppal, Gurmit S., MRCOphth, Balaggan, Kamaljit S., MRCOphth, Tufail, Adnan, MD, FRCOphth, Munro, Peter M.G., PhD, Milliken, Andrew B., FCOptom, Ali, Robin R., PhD, Rubin, Gary S., PhD, Aylward, G. William, MD, FRCOphth, da Cruz, Lyndon, PhD, FRCOphth

“…Purpose To assess excision of choroidal new vessels (CNV) combined with autologous transplantation of the equatorial retinal pigment epithelium (RPE) as a…”
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Real-Time In Vivo Imaging of Retinal Cell Apoptosis after Laser Exposure by Schmitz-Valckenberg, Steffen, Guo, Li, Maass, Annelie, Cheung, William, Vugler, Anthony, Moss, Stephen E, Munro, Peter M. G, Fitzke, Frederick W, Cordeiro, M. Francesca

“…To investigate whether the detection of apoptosing retinal cells (DARC) could detect cells undergoing apoptosis in a laser model of retinal damage. Laser…”
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Mutations in TOPORS Cause Autosomal Dominant Retinitis Pigmentosa with Perivascular Retinal Pigment Epithelium Atrophy by Chakarova, Christina F., Papaioannou, Myrto G., Khanna, Hemant, Lopez, Irma, Waseem, Naushin, Shah, Amna, Theis, Torsten, Friedman, James, Maubaret, Cecilia, Bujakowska, Kinga, Veraitch, Brotati, El-Aziz, Mai M. Abd, Prescott, De Quincy, Parapuram, Sunil K., Bickmore, Wendy A., Munro, Peter M.G., Gal, Andreas, Hamel, Christian P., Marigo, Valeria, Ponting, Chris P., Wissinger, Bernd, Zrenner, Eberhart, Matter, Karl, Swaroop, Anand, Koenekoop, Robert K., Bhattacharya, Shomi S.

“…We report mutations in the gene for topoisomerase I–binding RS protein ( TOPORS) in patients with autosomal dominant retinitis pigmentosa (adRP) linked to…”
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Basement membrane changes in capillaries of the ageing human retina by Powner, Michael B, Scott, Andrew, Zhu, Meidong, Munro, Peter M G, Foss, Alexander J E, Hageman, Gregory S, Gillies, Mark C, Fruttiger, Marcus

“…The ultrastructural appearance of retinal capillaries can yield important information about disease mechanisms, but is not well characterised in human post…”
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WASp‐dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts by Malinova, Dessislava, Fritzsche, Marco, Nowosad, Carla R., Armer, Hannah, Munro, Peter M. G., Blundell, Michael P., Charras, Guillaume, Tolar, Pavel, Bouma, Gerben, Thrasher, Adrian J.

“…Novel DC podosomes surround the central MHCII cluster to stabilize the IS; a driver role for the DC actin cytoskeleton. The immunological synapse is a highly…”
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Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration by Luhmann, Ulrich F.O., Carvalho, Livia S., Robbie, Scott J., Cowing, Jill A., Duran, Yanai, Munro, Peter M.G., Bainbridge, James W.B., Ali, Robin R.

“…Monocytes, macrophages, dendritic cells and microglia play critical roles in the local immune response to acute and chronic tissue injury and have been…”
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In Vitro Characterization of a Spontaneously Immortalized Human Muller Cell Line (MIO-M1) by Limb, G. Astrid, Salt, Thomas E, Munro, Peter M. G, Moss, Stephen E, Khaw, Peng T

“…To characterize a spontaneously immortalized human Müller cell line and to determine whether it retains the characteristics of primary isolated cells without…”
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Acute Corneal Calcification Following Chemical Injury by Daly, Mary, Tuft, Stephen J, Munro, Peter M. G

“…PURPOSE:To describe the clinical and ultrastructural features of 3 cases of acute corneal calcification following accidental chemical injury. METHODS:Three men…”
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The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors by Luhmann, Ulrich F O, Carvalho, Livia S, Holthaus, Sophia-Martha Kleine, Cowing, Jill A, Greenaway, Simon, Chu, Colin J, Herrmann, Philipp, Smith, Alexander J, Munro, Peter M G, Potter, Paul, Bainbridge, James W B, Ali, Robin R

“…Understanding phenotype-genotype correlations in retinal degeneration is a major challenge. Mutations in CRB1 lead to a spectrum of autosomal recessive retinal…”
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Correction: The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice by Anastasios Georgiadis, Marion Tschernutter, James W B Bainbridge, Kamaljit S Balaggan, Freya Mowat, Emma L West, Peter M G Munro, Adrian J Thrasher, Karl Matter, Maria S Balda, Robin R Ali

“…[This corrects the article DOI: 10.1371/journal.pone.0015730.]…”
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Inhibition of N-acetylaspartate production: implications for 1H MRS studies in vivo by Bates, T E, Strangward, M, Keelan, J, Davey, G P, Munro, P M, Clark, J B

“…The effect of specific irreversible inhibitors of complexes I, III, IV and V of the mitochondrial respiratory chain, (rotenone, myxothiazol, cyanide and…”
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Macular hole opercula. Ultrastructural features and clinicopathological correlation by Ezra, E, Munro, P M, Charteris, D G, Aylward, W G, Luthert, P J, Gregor, Z J

“…To investigate the ultrastructural features of idiopathic full-thickness macular hole (FTMH) opercula excised during vitrectomy and to correlate them with the…”
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Impact of engagement of FcepsilonRI and CC chemokine receptor 1 on mast cell activation and motility by Toda, Masako, Dawson, Maria, Nakamura, Takao, Munro, Peter M G, Richardson, Ricardo Micheler, Bailly, Maryse, Ono, Santa Jeremy

“…CC chemokines participate in the recruitment and activation of immune cells through CC chemokine receptors (CCRs). Here, we report that cross-talk between…”
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