Search Results - "Peter J. van der Spek"

The preconception Mediterranean dietary pattern in couples undergoing in vitro fertilization/intracytoplasmic sperm injection treatment increases the chance of pregnancy by Vujkovic, Marijana, B.Sc, de Vries, Jeanne H., Ph.D, Lindemans, Jan, Ph.D, Macklon, Nick S., Ph.D, van der Spek, Peter J., Ph.D, Steegers, Eric A.P., Ph.D, Steegers-Theunissen, Régine P.M., Ph.D

“…Objective To investigate associations between preconception dietary patterns and IVF/intracytoplasmic sperm injection (ICSI) outcomes validated by biomarkers…”
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Identification of candidate genes for developmental colour agnosia in a single unique family by Nijboer, Tanja C. W, Hessel, Ellen V. S, van Haaften, Gijs W, van Zandvoort, Martine J, van der Spek, Peter J, Troelstra, Christine, de Kovel, Carolien G. F, Koeleman, Bobby P. C, van der Zwaag, Bert, Brilstra, Eva H, Burbach, J. Peter H

“…Colour agnosia is a disorder that impairs colour knowledge (naming, recognition) despite intact colour perception. Previously, we have identified the first and…”
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Inactivation of IL11 Signaling Causes Craniosynostosis, Delayed Tooth Eruption, and Supernumerary Teeth by Nieminen, Pekka, Morgan, Neil V., Fenwick, Aimée L., Parmanen, Satu, Veistinen, Lotta, Mikkola, Marja L., van der Spek, Peter J., Giraud, Andrew, Judd, Louise, Arte, Sirpa, Brueton, Louise A., Wall, Steven A., Mathijssen, Irene M.J., Maher, Eamonn R., Wilkie, Andrew O.M., Kreiborg, Sven, Thesleff, Irma

“…Craniosynostosis and supernumerary teeth most often occur as isolated developmental anomalies, but they are also separately manifested in several malformation…”
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Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo by Zheng, Ping-Pin, Romme, Edwin, Spek, Peter J. van der, Dirven, Clemens M.F., Willemsen, Rob, Kros, Johan M.

“…Objective The overall permeability of the blood‐brain barrier (BBB) is regulated by specialized cerebral endothelial cells and their junctional complexes,…”
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Functional Analysis of Genetic Variation in the SECIS Element of Thyroid Hormone Activating Type 2 Deiodinase by Zevenbergen, Chantal, Groeneweg, Stefan, Swagemakers, Sigrid M A, de Jong, Arthur, Medici-Van den Herik, Evita, Rispens, Madzy, Klootwijk, Wim, Medici, Marco, de Rijke, Yolanda B, Meima, Marcel E, Larsen, P Reed, Chavatte, Laurent, Venter, Deon, Peeters, Robin P, Van der Spek, Peter J, Visser, W Edward

“…Abstract Context Thyroid hormone is important for normal brain development. The type 2 deiodinase (D2) controls thyroid hormone action in the brain by…”
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Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background by Alves, Celso Henrique, Bossers, Koen, Vos, Rogier M, Essing, Anke H W, Swagemakers, Sigrid, van der Spek, Peter J, Verhaagen, Joost, Wijnholds, Jan

“…In humans, the Crumbs homologue-1 (CRB1) gene is mutated in progressive types of autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. The…”
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Metabolomic Signatures for the Effects of Weight Loss Interventions on Severe Obesity in Children and Adolescents by Sohn, Min-Ji, Chae, Woori, Ko, Jae-Sung, Cho, Joo-Youn, Kim, Ji-Eun, Choi, Ji-Yeob, Jang, Han-Byul, Lee, Hye-Ja, Park, Sang-Ick, Park, Kyung-Hee, van der Spek, Peter J, Moon, Jin-Soo

“…Childhood obesity has increased worldwide, and many clinical and public interventions have attempted to reduce morbidity. We aimed to determine the metabolomic…”
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Gene expression and functional annotation of the human and mouse choroid plexus epithelium by Janssen, Sarah F, van der Spek, Sophie J F, Ten Brink, Jacoline B, Essing, Anke H W, Gorgels, Theo G M F, van der Spek, Peter J, Jansonius, Nomdo M, Bergen, Arthur A B

“…The choroid plexus epithelium (CPE) is a lobed neuro-epithelial structure that forms the outer blood-brain barrier. The CPE protrudes into the brain ventricles…”
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Immunologic mechanisms associated with STAT6 gain-of-function variant identified in early-onset allergies by Suratannon, Narissara, Dik, Willem, Israsena, Nipan, Ingrungruanglert, Praewphan, Dalm, Virgil A.S.H., Buranapraditkun, Supranee, Swagemakers, Sigrid, IJspeert, Hanna, van der Spek van der Spek, Peter J., Chatchatee, Pantipa, van Hagen, Martin

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Evaluation of Immunohistochemical Markers, CK17 and SOX2, as Adjuncts to p53 for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia (dVIN) by Dasgupta, Shatavisha, Koljenović, Senada, van den Bosch, Thierry P P, Swagemakers, Sigrid M A, van der Hoeven, Nick M A, van Marion, Ronald, van der Spek, Peter J, van Doorn, Helena C, van Kemenade, Folkert J, Ewing-Graham, Patricia C

“…Histological diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN), the precursor of human papillomavirus (HPV)-independent vulvar squamous cell…”
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Galaxy mothur Toolset (GmT): a user-friendly application for 16S rRNA gene sequencing analysis using mothur by Hiltemann, Saskia D, Boers, Stefan A, van der Spek, Peter J, Jansen, Ruud, Hays, John P, Stubbs, Andrew P

“…Abstract Background The determination of microbial communities using the mothur tool suite (https://www.mothur.org) is well established. However, mothur…”
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A new strategy to identify and annotate human RPE-specific gene expression by Booij, Judith C, ten Brink, Jacoline B, Swagemakers, Sigrid M A, Verkerk, Annemieke J M H, Essing, Anke H W, van der Spek, Peter J, Bergen, Arthur A B

“…To identify and functionally annotate cell type-specific gene expression in the human retinal pigment epithelium (RPE), a key tissue involved in age-related…”
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First trimester physiological development of the fetal foot position using three‐dimensional ultrasound in virtual reality by Bogers, Hein, Rifouna, Maria S., Cohen‐Overbeek, Titia E., Koning, Anton H. J., Willemsen, Sten P., van der Spek, Peter J., Steegers‐Theunissen, Régine P. M., Exalto, Niek, Steegers, Eric A. P.

“…Aim In anatomic studies of the embryo, it has been established that during the development of the lower limb, several changes in foot position can be observed…”
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Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA–minus RNA sequencing data by Hoogstrate, Youri, Komor, Malgorzata A, Böttcher, René, van Riet, Job, van de Werken, Harmen J G, van Lieshout, Stef, Hoffmann, Ralf, van den Broek, Evert, Bolijn, Anne S, Dits, Natasja, Sie, Daoud, van der Meer, David, Pepers, Floor, Bangma, Chris H, van Leenders, Geert J L H, Smid, Marcel, French, Pim J, Martens, John W M, van Workum, Wilbert, van der Spek, Peter J, Janssen, Bart, Caldenhoven, Eric, Rausch, Christian, de Jong, Mark, Stubbs, Andrew P, Meijer, Gerrit A, Fijneman, Remond J A, Jenster, Guido W

“…Abstract Background Fusion genes are typically identified by RNA sequencing (RNA-seq) without elucidating the causal genomic breakpoints. However,…”
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Gene expression and functional annotation of the human ciliary body epithelia by Janssen, Sarah F, Gorgels, Theo G M F, Bossers, Koen, Ten Brink, Jacoline B, Essing, Anke H W, Nagtegaal, Martijn, van der Spek, Peter J, Jansonius, Nomdo M, Bergen, Arthur A B

“…The ciliary body (CB) of the human eye consists of the non-pigmented (NPE) and pigmented (PE) neuro-epithelia. We investigated the gene expression of NPE and…”
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Plasticity mechanisms of genetically distinct Purkinje cells by Voerman, Stijn, Broersen, Robin, Swagemakers, Sigrid M. A., De Zeeuw, Chris I., Spek, Peter J.

“…Despite its uniform appearance, the cerebellar cortex is highly heterogeneous in terms of structure, genetics and physiology. Purkinje cells (PCs), the…”
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On the origin of proteins in human drusen: The meet, greet and stick hypothesis by Bergen, Arthur A., Arya, Swati, Koster, Céline, Pilgrim, Matthew G., Wiatrek-Moumoulidis, Dagmara, van der Spek, Peter J., Hauck, Stefanie M., Boon, Camiel J.F., Emri, Eszter, Stewart, Alan J., Lengyel, Imre

“…Retinal drusen formation is not only a clinical hallmark for the development of age-related macular degeneration (AMD) but also for other disorders, such as…”
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Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade by Moltzer, Els, te Riet, Luuk, Swagemakers, Sigrid M A, van Heijningen, Paula M, Vermeij, Marcel, van Veghel, Richard, Bouhuizen, Angelique M, van Esch, Joep H M, Lankhorst, Stephanie, Ramnath, Natasja W M, de Waard, Monique C, Duncker, Dirk J, van der Spek, Peter J, Rouwet, Ellen V, Danser, A H Jan, Essers, Jeroen

“…Medial degeneration is a key feature of aneurysm disease and aortic dissection. In a murine aneurysm model we investigated the structural and functional…”
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CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue by van Riet, Job, Saha, Chinmoy, Strepis, Nikolaos, Brouwer, Rutger W. W., Martens-Uzunova, Elena S., van de Geer, Wesley S., Swagemakers, Sigrid M. A., Stubbs, Andrew, Halimi, Yassir, Voogd, Sanne, Tanmoy, Arif Mohammad, Komor, Malgorzata A., Hoogstrate, Youri, Janssen, Bart, Fijneman, Remond J. A., Niknafs, Yashar S., Chinnaiyan, Arul M., van IJcken, Wilfred F. J., van der Spek, Peter J., Jenster, Guido, Louwen, Rogier

“…Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) have been identified in bacteria, archaea and mitochondria of plants, but not in…”
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Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin by Papadopoulos, Petros, Gutiérrez, Laura, Scerri, Christian A, van IJcken, Wilfred, von Lindern, Marieke, Cassar, Wilhelmina, Felice, Alex E, Grech, Godfrey, Hou, Jun, Fanis, Pavlos, Phylactides, Marios, Georgitsi, Marianthi, Verkerk, Annemieke J M H, Özgür, Zeliha, Bugeja, Marisa, van der Spek, Peter J, Patrinos, George P, Borg, Joseph, Galdies, Ruth, Grosveld, Frank G, Gillemans, Nynke, Philipsen, Sjaak

“…Hereditary persistence of fetal hemoglobin (HPFH) is characterized by persistent high levels of fetal hemoglobin (HbF) in adults. Several contributory factors,…”
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