Search Results - "Peter Inglesby"

Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records by Thompson, Ellen J., Williams, Dylan M., Walker, Alex J., Mitchell, Ruth E., Niedzwiedz, Claire L., Yang, Tiffany C., Huggins, Charlotte F., Kwong, Alex S. F., Silverwood, Richard J., Di Gessa, Giorgio, Bowyer, Ruth C. E., Northstone, Kate, Hou, Bo, Green, Michael J., Dodgeon, Brian, Doores, Katie J., Duncan, Emma L., Williams, Frances M. K., Steptoe, Andrew, Porteous, David J., McEachan, Rosemary R. C., Tomlinson, Laurie, Goldacre, Ben, Patalay, Praveetha, Ploubidis, George B., Katikireddi, Srinivasa Vittal, Tilling, Kate, Rentsch, Christopher T., Timpson, Nicholas J., Chaturvedi, Nishi, Steves, Claire J.

“…The frequency of, and risk factors for, long COVID are unclear among community-based individuals with a history of COVID-19. To elucidate the burden and…”
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Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform by Bhaskaran, Krishnan, Rentsch, Christopher T, Hickman, George, Hulme, William J, Schultze, Anna, Curtis, Helen J, Wing, Kevin, Warren-Gash, Charlotte, Tomlinson, Laurie, Bates, Chris J, Mathur, Rohini, MacKenna, Brian, Mahalingasivam, Viyaasan, Wong, Angel, Walker, Alex J, Morton, Caroline E, Grint, Daniel, Mehrkar, Amir, Eggo, Rosalind M, Inglesby, Peter, Douglas, Ian J, McDonald, Helen I, Cockburn, Jonathan, Williamson, Elizabeth J, Evans, David, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen Jw, Bacon, Sebastian, Smeeth, Liam, Goldacre, Ben

“…There is concern about medium to long-term adverse outcomes following acute Coronavirus Disease 2019 (COVID-19), but little relevant evidence exists. We aimed…”
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Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform by Bhaskaran, Krishnan, Bacon, Sebastian, Evans, Stephen JW, Bates, Chris J, Rentsch, Christopher T, MacKenna, Brian, Tomlinson, Laurie, Walker, Alex J, Schultze, Anna, Morton, Caroline E, Grint, Daniel, Mehrkar, Amir, Eggo, Rosalind M, Inglesby, Peter, Douglas, Ian J, McDonald, Helen I, Cockburn, Jonathan, Williamson, Elizabeth J, Evans, David, Curtis, Helen J, Hulme, William J, Parry, John, Hester, Frank, Harper, Sam, Spiegelhalter, David, Smeeth, Liam, Goldacre, Ben

“…Mortality from COVID-19 shows a strong relationship with age and pre-existing medical conditions, as does mortality from other causes. We aimed to investigate…”
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Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: An observational cohort study using the OpenSAFELY platform by Samuel, Miriam, Park, Robin Y, Eastwood, Sophie V, Eto, Fabiola, Morton, Caroline E, Stow, Daniel, Bacon, Sebastian, Mehrkar, Amir, Morley, Jessica, Dillingham, Iain, Inglesby, Peter, Hulme, William J, Khunti, Kamlesh, Mathur, Rohini, Valabhji, Jonathan, MacKenna, Brian, Finer, Sarah

“…Obesity and rapid weight gain are established risk factors for noncommunicable diseases and have emerged as independent risk factors for severe disease…”
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Risk of emergency hospital admission related to adverse events after antibiotic treatment in adults with a common infection: impact of COVID-19 and derivation and validation of risk prediction models by Zhong, Xiaomin, Palin, Victoria, Ashcroft, Darren M, Goldacre, Ben, MacKenna, Brian, Mehrkar, Amir, Bacon, Sebastian C J, Massey, Jon, Inglesby, Peter, Hand, Kieran, Pate, Alexander, van Staa, Tjeerd Pieter

“…With the global challenge of antimicrobial resistance intensified during the COVID-19 pandemic, evaluating adverse events (AEs) post-antibiotic treatment for…”
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Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY by Green, Amelia, Curtis, Helen, Hulme, William, Williamson, Elizabeth, McDonald, Helen, Bhaskaran, Krishnan, Rentsch, Christopher, Schultze, Anna, MacKenna, Brian, Mahalingasivam, Viyaasan, Tomlinson, Laurie, Walker, Alex, Fisher, Louis, Massey, Jon, Andrews, Colm, Hopcroft, Lisa, Morton, Caroline, Croker, Richard, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Evans, David, Inglesby, Peter, Hickman, George, Ward, Tom, Davy, Simon, Mathur, Rohini, Tazare, John, Eggo, Rosalind, Wing, Kevin, Wong, Angel, Forbes, Harriet, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian, Evans, Stephen, Smeeth, Liam, Goldacre, Ben

“…While the vaccines against COVID-19 are highly effective, COVID-19 vaccine breakthrough is possible despite being fully vaccinated. With SARS-CoV-2 variants…”
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OpenSAFELY: Representativeness of electronic health record platform OpenSAFELY-TPP data compared to the population of England by Andrews, Colm, Schultze, Anna, Curtis, Helen, Hulme, William, Tazare, John, Evans, Stephen, Mehrkar, Amir, Bacon, Sebastian, Hickman, George, Bates, Christopher, Parry, John, Hester, Frank, Harper, Sam, Cockburn, Jonathan, Evans, David, Ward, Tom, Davy, Simon, Inglesby, Peter, Goldacre, Ben, MacKenna, Brian, Tomlinson, Laurie, Walker, Alex

“…Since its inception in March 2020, data from the OpenSAFELY-TPP electronic health record platform has been used for more than 20 studies relating to the global…”
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Consistency, completeness and external validity of ethnicity recording in NHS primary care records: a cohort study in 25 million patients' records at source using OpenSAFELY by Andrews, Colm D, Mathur, Rohini, Massey, Jon, Park, Robin, Curtis, Helen J, Hopcroft, Lisa, Mehrkar, Amir, Bacon, Seb, Hickman, George, Smith, Rebecca, Evans, David, Ward, Tom, Davy, Simon, Inglesby, Peter, Dillingham, Iain, Maude, Steven, O'Dwyer, Thomas, Butler-Cole, Ben F C, Bridges, Lucy, Bates, Chris, Parry, John, Hester, Frank, Harper, Sam, Cockburn, Jonathan, Goldacre, Ben, MacKenna, Brian, Tomlinson, Laurie A, Walker, Alex J, Hulme, William J

“…Ethnicity is known to be an important correlate of health outcomes, particularly during the COVID-19 pandemic, where some ethnic groups were shown to be at…”
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Impact of first UK COVID-19 lockdown on hospital admissions: Interrupted time series study of 32 million people by Shah, Syed Ahmar, Brophy, Sinead, Kennedy, John, Fisher, Louis, Walker, Alex, Mackenna, Brian, Curtis, Helen, Inglesby, Peter, Davy, Simon, Bacon, Seb, Goldacre, Ben, Agrawal, Utkarsh, Moore, Emily, Simpson, Colin R, Macleod, John, Cooksey, Roxane, Sheikh, Aziz, Katikireddi, Srinivasa Vittal

“…Uncontrolled infection and lockdown measures introduced in response have resulted in an unprecedented challenge for health systems internationally. Whether…”
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Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65 by Schultze, Anna, Nightingale, Emily, Evans, David, Hulme, William, Rosello, Alicia, Bates, Chris, Cockburn, Jonathan, MacKenna, Brian, Curtis, Helen J, Morton, Caroline E, Croker, Richard, Bacon, Seb, McDonald, Helen I, Rentsch, Christopher T, Bhaskaran, Krishnan, Mathur, Rohini, Tomlinson, Laurie A, Williamson, Elizabeth J, Forbes, Harriet, Tazare, John, Grint, Daniel, Walker, Alex J, Inglesby, Peter, DeVito, Nicholas J, Mehrkar, Amir, Hickman, George, Davy, Simon, Ward, Tom, Fisher, Louis, Green, Amelia CA, Wing, Kevin, Wong, Angel YS, McManus, Robert, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen JW, Douglas, Ian J, Smeeth, Liam, Eggo, Rosalind M, Goldacre, Ben, Leon, David A

“…Residents in care homes have been severely impacted by COVID-19. We describe trends in the mortality risk among residents of care homes compared to private…”
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Healthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway: A cohort study using OpenSAFELY-TPP by Lemanska, Agnieszka, Andrews, Colm, Fisher, Louis, Bacon, Seb, Frampton, Adam E, Mehrkar, Amir, Inglesby, Peter, Davy, Simon, Roberts, Keith, Patalay, Praveetha, Goldacre, Ben, MacKenna, Brian, Walker, Alex J

“…Healthcare across all sectors, in the UK and globally, was negatively affected by the COVID-19 pandemic. We analysed healthcare services delivered to people…”
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Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults' primary care records in England through OpenSAFELY by Fisher, Louis, Curtis, Helen J, Croker, Richard, Wiedemann, Milan, Speed, Victoria, Wood, Christopher, Brown, Andrew, Hopcroft, Lisa E M, Higgins, Rose, Massey, Jon, Inglesby, Peter, Morton, Caroline E, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Hickman, George, Macdonald, Orla, Lewis, Tom, Wood, Marion, Myers, Martin, Samuel, Miriam, Conibere, Robin, Baqir, Wasim, Sood, Harpreet, Drury, Charles, Collison, Kiren, Bates, Chris, Evans, David, Dillingham, Iain, Ward, Tom, Davy, Simon, Smith, Rebecca M, Hulme, William, Green, Amelia, Parry, John, Hester, Frank, Harper, Sam, Cockburn, Jonathan, O'Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Griffiths, Paul, Fowles, Aaron, Parkes, Nasreen, MacKenna, Brian, Goldacre, Ben

“…The COVID-19 pandemic has had a significant impact on delivery of NHS care. We have developed the OpenSAFELY Service Restoration Observatory (SRO) to develop…”
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The Use of Online Consultation Systems or Remote Consulting in England Characterized Through the Primary Care Health Records of 53 Million People in the OpenSAFELY Platform: Retrospective Cohort Study by Fonseca, Martina, MacKenna, Brian, Mehrkar, Amir, Walters, Caroline E, Hickman, George, Pearson, Jonathan, Fisher, Louis, Inglesby, Peter, Bacon, Seb, Davy, Simon, Hulme, William, Goldacre, Ben, Koffman, Ofra, Bakhai, Minal

“…The National Health Service (NHS) Long Term Plan, published in 2019, committed to ensuring that every patient in England has the right to digital-first primary…”
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Software development skills for health data researchers by Morton, Caroline, Devito, Nicholas, Morley, Jessica, Dillingham, Iain, Schultze, Anna, Bacon, Sebastian, Inglesby, Peter, Maude, Steven, Goldacre, Ben

“…If the quality of this analytic code cannot be reasonably assured, then results cannot be trusted: programming errors have resulted in high profile…”
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Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data: Retrospective Database Study by Hopcroft, Lisa Em, Curtis, Helen J, Croker, Richard, Pretis, Felix, Inglesby, Peter, Evans, David, Bacon, Sebastian, Goldacre, Ben, Walker, Alex J, MacKenna, Brian

“…We have previously demonstrated that opioid prescribing increased by 127% between 1998 and 2016. New policies aimed at tackling this increasing trend have been…”
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Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study by Wong, Angel Y S, Tomlinson, Laurie A, Brown, Jeremy P, Elson, William, Walker, Alex J, Schultze, Anna, Morton, Caroline E, Evans, David, Inglesby, Peter, MacKenna, Brian, Bhaskaran, Krishnan, Rentsch, Christopher T, Powell, Emma, Williamson, Elizabeth, Croker, Richard, Bacon, Seb, Hulme, William, Bates, Chris, Curtis, Helen J, Mehrkar, Amir, Cockburn, Jonathan, McDonald, Helen I, Mathur, Rohini, Wing, Kevin, Forbes, Harriet, Eggo, Rosalind M, Evans, Stephen J W, Smeeth, Liam, Goldacre, Ben, Douglas, Ian J

“…Thromboembolism has been reported as a consequence of severe COVID-19. Although warfarin is a commonly used anticoagulant, it acts by antagonising vitamin K,…”
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OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic by Curtis, Helen J, MacKenna, Brian, Walker, Alex J, Croker, Richard, Mehrkar, Amir, Morton, Caroline, Bacon, Seb, Hickman, George, Inglesby, Peter, Bates, Chris, Evans, David, Ward, Tom, Cockburn, Jonathan, Davy, Simon, Bhaskaran, Krishnan, Schultze, Anna, Rentsch, Christopher T, Williamson, Elizabeth, Hulme, William, Tomlinson, Laurie, Mathur, Rohini, Drysdale, Henry, Eggo, Rosalind M, Wong, Angel Yun, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian, Smeeth, Liam, Goldacre, Ben

“…BackgroundEarly in the COVID-19 pandemic, the National Health Service (NHS) recommended that appropriate patients anticoagulated with warfarin should be…”
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Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY by Wiedemann, Milan, Speed, Victoria, Cunningham, Christine, Higgins, Rose, Curtis, Helen J, Andrews, Colm, Fisher, Louis, Hopcroft, Lisa, Rentsch, Christopher T, Mahalingasivam, Viyaasan, Tomlinson, Laurie, Morton, Caroline, Samuel, Miriam, Green, Amelia, Wood, Christopher, Brown, Andrew D, Massey, Jon, Walters, Caroline, Smith, Rebecca M, Inglesby, Peter, Evans, David, Maude, Steven, Dillingham, Iain, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, McManus, Richard J, Goldacre, Ben, MacKenna, Brian

“…BackgroundThe COVID-19 pandemic disrupted cardiovascular disease management in primary care in England.ObjectiveTo describe the impact of the pandemic on blood…”
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Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP by Cunningham, Christine, Fisher, Louis, Wood, Christopher, Speed, Victoria, Brown, Andrew D, Curtis, Helen, Higgins, Rose, Croker, Richard, Butler-Cole, Ben FC, Evans, David, Inglesby, Peter, Dillingham, Iain, Bacon, Sebastian CJ, Beech, Elizabeth, Hand, Kieran, Davy, Simon, Ward, Tom, Hickman, George, Bridges, Lucy, O'Dwyer, Thomas, Maude, Steven, Smith, Rebecca M, Mehrkar, Amir, Hart, Liam C, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Goldacre, Ben, MacKenna, Brian

“…ObjectiveTo investigate the effect of the covid-19 pandemic on the number of patients with group A streptococcal infections and related antibiotic…”
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Impact of the COVID-19 pandemic on antipsychotic prescribing in individuals with autism, dementia, learning disability, serious mental illness or living in a care home: a federated analysis of 59 million patients’ primary care records in situ using OpenSAFELY by Macdonald, Orla, Green, Amelia, Walker, Alex, Curtis, Helen, Croker, Richard, Brown, Andrew, Butler-Cole, Ben, Andrews, Colm, Massey, Jon, Inglesby, Peter, Morton, Caroline, Fisher, Louis, Morley, Jessica, Mehrkar, Amir, Bacon, Sebastian, Davy, Simon, Evans, David, Dillingham, Iain, Ward, Tom, Hulme, William, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, O'Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Parkes, Nasreen, Wood, Ian, Goldacre, Ben, Mackenna, Brian

“…BackgroundThe COVID-19 pandemic affected how care was delivered to vulnerable patients, such as those with dementia or learning disability.ObjectiveTo explore…”
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