Search Results - "Peter Gerold"
-
1
Signal Transduction in Macrophages by Glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: Activation of Protein Tyrosine Kinases and Protein Kinase C by Inositolglycan and Diacylglycerol Moieties
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-1997)“…The perturbation of various glycosylphosphatidylinositol (GPI)-anchored surface proteins imparts profound regulatory signals to macrophages, lymphocytes and…”
Get full text
Journal Article -
2
Structural analysis of the glycosyl-phosphatidylinositol membrane anchor of the merozoite surface proteins-1 and -2 of Plasmodium falciparum
Published in Molecular and biochemical parasitology (1996)“…Plasmodium falciparum accumulates the two merozoite surface proteins-1 and -2 during schizogony. Both proteins are proposed to be anchored in membranes by…”
Get full text
Journal Article -
3
Membrane Topology and Transient Acylation of Toxoplasma gondii Glycosylphosphatidylinositols
Published in Eukaryotic Cell (01-08-2006)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
4
Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesis
Published in Biochemical journal (15-05-1998)“…An increasing number of plasma membrane proteins have been shown to be attached to the membrane via a glycosylphosphatidylinositol (GPI) moiety. All eukaryotes…”
Get full text
Journal Article -
5
Metabolic Labeling and Structural Analysis of Glycosylphosphatidylinositols from Parasitic Protozoa
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Glycosylphosphatidylinositol (GPI) is a complex glycolipid structure that acts as a membrane anchor for many cell-surface proteins of eukaryotes. GPI-anchored…”
Get more information
Journal Article -
6
Plasmodium falciparum: glycosylation status of Plasmodium falciparum circumsporozoite protein expressed in the baculovirus system
Published in Experimental parasitology (01-05-2002)“…We expressed the main surface antigen of Plasmodium falciparum sporozoites, the circumsporozoite protein (CSP), in High Five ( Trichoplusia ni) insect cells…”
Get full text
Journal Article -
7
The biosynthesis and post-translational modification of Pbs21 an ookinete-surface protein of Plasmodium berghei
Published in Molecular and biochemical parasitology (25-01-1999)“…Radiolabelled methionine incorporation into synchronised Plasmodium berghei gametocytes or ookinete cultures, showed that Pbs21 is not synthesised in…”
Get full text
Journal Article -
8
Structural analysis of free and protein-bound glycosyl-phosphatidylinositols of Neospora caninum
Published in Molecular and biochemical parasitology (05-01-2000)“…Neospora caninum is an intracellular protozoan parasite, closely related to Toxoplasma gondii. In T. gondii, the tachyzoite surface contains…”
Get full text
Journal Article -
9
Glycosyl-phosphatidylinositols of : Two Common Precursors but a New Protein-anchor
Published in Journal of molecular biology (01-08-1996)Get full text
Journal Article -
10
Metabolic labeling and structural analysis of glycosylphosphatidylinositols from parasitic protozoa
Published in Methods in molecular biology (Clifton, N.J.) (2008)“…Glycosylphosphatidylinositol (GPI) is a complex glycolipid structure that acts as a membrane anchor for many cell-surface proteins of eukaryotes. GPI-anchored…”
Get more information
Journal Article -
11
Biosynthesis of glycosphingolipids de-novo by the human malaria parasite Plasmodium falciparum
Published in Molecular and biochemical parasitology (15-01-2001)“…Glycolipids are important components of cellular membranes involved in various biological functions. In this report we describe the identification of the…”
Get full text
Journal Article -
12
Glycosylphosphatidylinositol toxin of Plasmodium up-regulates intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin expression in vascular endothelial cells and increases leukocyte and parasite cytoadherence via tyrosine kinase-dependent signal transduction
Published in The Journal of immunology (1950) (01-03-1996)“…In this study we demonstrate that glycosylphosphatidylinositol (GPI) of malaria parasite origin directly increases cell adhesion molecule expression in…”
Get full text
Journal Article -
13
Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway
Published in The Journal of immunology (1950) (01-03-1996)“…In this study, we demonstrate that glycosylphosphatidylinositol (GPI) is a major toxin of Plasmodium falciparum origin responsible for nitric oxide (NO)…”
Get full text
Journal Article -
14
Identification and characterisation of Toxoplasma gondii protein farnesyltransferase
Published in International journal for parasitology (01-11-2001)“…Prenylated proteins are involved in the regulation of DNA replication and cell cycling and have important roles in the regulation of cell proliferation…”
Get full text
Journal Article -
15
Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis
Published in The EMBO journal (01-11-1997)“…Glycosylphosphatidylinositol (GPI)‐anchoring represents a mechanism for attaching proteins to the cell surface that is used among all eukaryotes. A common core…”
Get full text
Journal Article -
16
Glycosylphosphatidylinositols synthesized by asexual erythrocytic stages of the malarial parasite, Plasmodium falciparum. Candidates for plasmodial glycosylphosphatidylinositol membrane anchor precursors and pathogenicity factors
Published in The Journal of biological chemistry (28-01-1994)“…Plasmodium falciparum is the causative agent of malaria tropica in man. Biochemical studies were focused on the asexual, intraerythrocytic stages of P…”
Get full text
Journal Article -
17
Substrate Specificity of the Plasmodium falciparum Glycosylphosphatidylinositol Biosynthetic Pathway and Inhibition by Species-Specific Suicide Substrates
Published in Biochemistry (Easton) (15-10-2002)“…The substrate specificities of the early glycosylphosphatidylinositol biosynthetic enzymes of Plasmodium were determined using substrate analogues of…”
Get full text
Journal Article -
18
Evidence for de novo sphingolipid biosynthesis in Toxoplasma gondii
Published in International journal for parasitology (01-06-2002)“…Glycolipids are important components of cellular membranes involved in various biological functions. In this report, we describe the identification of the de…”
Get full text
Journal Article -
19
-
20
The Candida albicans Phospholipomannan Is a Family of Glycolipids Presenting Phosphoinositolmannosides with Long Linear Chains of β-1,2-Linked Mannose Residues
Published in The Journal of biological chemistry (22-10-1999)“…In a series of studies, we have shown thatCandida albicans synthesizes a glycolipid, phospholipomannan (PLM), which reacted with antibodies specific for…”
Get full text
Journal Article