Search Results - "Peter, Wipfler"
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COVID-19 severity and mortality in multiple sclerosis are not associated with immunotherapy: Insights from a nation-wide Austrian registry
Published in PloS one (27-07-2021)“…Background The COVID-19 pandemic challenges neurologists in counselling patients with multiple sclerosis (pwMS) regarding their risk by SARS-CoV-2 and in…”
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Tick-Borne Encephalitis Virus RNA Found in Frozen Goat’s Milk in a Family Outbreak
Published in International journal of molecular sciences (01-10-2022)“…Tick-borne encephalitis (TBE) is one of the commonest arthropod-borne viral diseases in Middle-East Europe and North Asia. The main reservoir of the virus is…”
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Immunomodulatory Aspects of Therapeutic Plasma Exchange in Neurological Disorders-A Pilot Study
Published in International journal of molecular sciences (31-03-2023)“…Therapeutic plasma exchange (TPE) is used for drug-resistant neuroimmunological disorders, but its mechanism of action remains poorly understood. We therefore…”
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Serum Neurofilament Light Chain as Biomarker for Cladribine-Treated Multiple Sclerosis Patients in a Real-World Setting
Published in International journal of molecular sciences (01-02-2023)“…Serum neurofilament light chain (sNfL) is an intensely investigated biomarker in multiple sclerosis (MS). The aim of this study was to explore the impact of…”
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Long‐term outcome after COVID‐19 infection in multiple sclerosis: A nation‐wide multicenter matched‐control study
Published in European journal of neurology (01-10-2022)“…Background and purpose Long‐term outcome after COVID‐19 in patients with multiple sclerosis (pwMS) has scarcely been studied, and controlled data are lacking…”
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The CXCL13/CXCR5-chemokine axis in neuroinflammation: evidence of CXCR5+CD4 T cell recruitment to CSF
Published in Fluids and barriers of the CNS (26-08-2021)“…C-X-C chemokine ligand 13 (CXCL13) is frequently elevated in cerebrospinal fluid (CSF) in a variety of inflammatory central nervous system (CNS) diseases, has…”
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The CXCL13/CXCR5 Immune Axis in Health and Disease—Implications for Intrathecal B Cell Activities in Neuroinflammation
Published in Cells (Basel, Switzerland) (25-08-2022)“…The chemokine C-X-C- ligand 13 (CXCL13) is a major B cell chemoattractant to B cell follicles in secondary lymphoid organs (SLO) that proposedly recruits B…”
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Cerebrospinal fluid CXLC13 indicates disease course in neuroinfection: an observational study
Published in Journal of neuroinflammation (19-01-2019)“…The chemokine CXCL13 is an intensively investigated biomarker in Lyme neuroborreliosis (LNB). Its role in other neuroinfections is increasingly recognized but…”
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Role and Relevance of Cerebrospinal Fluid Cells in Diagnostics and Research: State-of-the-Art and Underutilized Opportunities
Published in Diagnostics (Basel) (30-12-2021)“…Cerebrospinal fluid (CSF) has recently experienced a revival in diagnostics and research. However, little progress has been made regarding CSF cell analysis…”
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Chemokine CXCL13 in serum, CSF and blood-CSF barrier function: evidence of compartment restriction
Published in Fluids and barriers of the CNS (24-02-2020)“…Elevation of the chemokine CXCL13 in CSF frequently occurs during active and acute CNS inflammatory processes and presumably is associated with B cell-related…”
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Long-term immunological consequences of anti-CD20 therapies on humoral responses to COVID-19 vaccines in multiple sclerosis: an observational study
Published in Therapeutic advances in neurological disorders (01-04-2022)“…Background: Anti-CD20 therapies induce pronounced B-cell depletion and blunt humoral responses to vaccines. Recovery kinetics of anti-CD20 therapy-mediated…”
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Tetravalent Influenza Vaccine Is Not Associated With Neuroaxonal Damage in Multiple Sclerosis Patients
Published in Frontiers in immunology (26-08-2021)“…BackgroundEfficacy of vaccines and disease activity linked to immunization are major concerns among people with multiple sclerosis (pwMS). ObjectiveTo assess…”
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Critical Illness in Patients with Multiple Sclerosis: A Matched Case-Control Study
Published in PloS one (31-05-2016)“…Over the course of multiple sclerosis (MS) several conditions may arise that require critical care. We aimed to study the reasons for admission and outcome in…”
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Humoral Response to SARS-CoV-2 Antigen in Patients Treated with Monoclonal Anti-CD20 Antibodies: It Is Not All about B Cell Recovery
Published in Neurology international (16-11-2022)“…Anti-CD20 therapies decrease the humoral response to SARS-CoV-2 immunization. We aimed to determine the extent of the humoral response to SARS-CoV-2 antigens…”
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Pre-Existing Humoral Immunological Memory Is Retained in Patients with Multiple Sclerosis Receiving Cladribine Therapy
Published in Biomedicines (31-10-2021)“…Cladribine (CLAD) is a lymphodepleting agent approved for active relapsing multiple sclerosis (MS). The impact of CLAD on the adaptive humoral immune system…”
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Adaptive Immune Responses in a Multiple Sclerosis Patient with Acute Varicella-Zoster Virus Reactivation during Treatment with Fingolimod
Published in International journal of molecular sciences (10-09-2015)“…Fingolimod, an oral sphingosine 1-phosphate (S1P) receptor modulator, is approved for the treatment of relapsing forms of multiple sclerosis (MS). The…”
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Lymphocyte subsets show different response patterns to in vivo bound natalizumab--a flow cytometric study on patients with multiple sclerosis
Published in PloS one (20-02-2012)“…Natalizumab is an effective monoclonal antibody therapy for the treatment of relapsing-remitting multiple sclerosis (RRMS) and interferes with immune cell…”
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Tumefactive MS lesions under fingolimod: A case report and literature review
Published in Neurology (05-11-2013)“…OBJECTIVE:To report about a possible association between fingolimod treatment and tumefactive demyelinating lesions (TDL) as seen in a patient developing…”
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Beyond T cell toxicity-Intrathecal chemokine C-X-C motif ligand indicating B cell involvement in immune-related adverse events following checkpoint inhibition: A two-case series and literature review
Published in European journal of neurology (01-07-2024)“…This study was undertaken to raise awareness of a role of B cells in immune checkpoint inhibitor (ICI)-associated neurological immune-related adverse events…”
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