Search Results - "Pestka, J.J"

Mechanisms of deoxynivalenol-induced gene expression and apoptosis by Pestka, J.J.

“…Fusarium infection of agricultural staples such as wheat, barley and corn with concurrent production of deoxynivalenol (DON) and other trichothecene mycotoxins…”
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Production of four macrocyclic trichothecenes by Stachybotrys chartarum during its development on different building materials as measured by UPLC-MS/MS by Aleksic, B., Bailly, S., Draghi, M., Pestka, J.J., Oswald, I.P., Robine, E., Bailly, J.D., Lacroix, M.Z.

“…Stachybotrys chartarum is a fungal contaminant of damp indoor environments that can produce several toxins belonging to the family of macrocyclic…”
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Growth and Viability of Commercial Bifidobacterium spp in Skim Milk Containing Oligosaccharides and Inulin by Shin, H.-S., Lee, J.-H., Pestka, J.J., Ustunol, Z.

“…ABSTRACT Two commercial strains of Bifidobacterium spp (Bf ‐1 and Bf ‐6) were cultured in 12% (w/w) reconstituted nonfat dry milk (NDM) containing 0, 0.5, 1.0,…”
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Deoxynivalenol and satratoxin G potentiate proinflammatory cytokine and macrophage inhibitory protein 2 induction by Listeria and Salmonella in the macrophage by Mbandi, E, Pestka, J J

“…Health risks from microbial pathogens and toxins encountered in food and the environment continue to be of worldwide concern. The purpose of this research was…”
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Ingestion of yogurt containing Lactobacillus acidophilus and Bifidobacterium to potentiate immunoglobulin A responses to cholera toxin in mice by Tejada-Simon, M V, Lee, J H, Ustunol, Z, Pestka, J J

“…Lactic acid bacteria have been reported to have benefits for the prevention and treatment of some forms of diarrhea and related conditions. To determine…”
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Induction of Cytokine mRNAs in Mice After Oral Exposure to the Trichothecene Vomitoxin (Deoxynivalenol): Relationship to Toxin Distribution and Protein Synthesis Inhibition by Azconaolivera, J.I., Ouyang, Y., Murtha, J., Chu, F.S., Pestka, J.J.

“…The effects of oral exposure to 0, 5, and 25 mg/kg body wt vomitoxin (VT) on cytokine mRNA levels in spleen, Peyer′s patches (PP), liver, kidney, and small…”
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Deoxynivalenol: Toxicity, mechanisms and animal health risks by Pestka, James J.

“…Trichothecene contamination of agricultural staples such as wheat, barley and maize during Fusarium colonization is an increasingly common problem possibly…”
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Effects of tumor necrosis factor type 1 and 2 receptor deficiencies on anorexia, growth and IgA dysregulation in mice exposed to the trichothecene vomitoxin by Pestka, J.J, Zhou, H.-R

“…Dietary exposure of mice to vomitoxin (VT), a trichothecene mycotoxin, causes anorexia and impaired growth as well as inducing elevated serum IgA and kidney…”
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Differential cytokine production in clonal macrophage and T-cell lines cultured with bifidobacteria by Marin, M L, Lee, J H, Murtha, J, Ustunol, Z, Pestka, J J

“…When used in commercial fermented dairy products, bifidobacteria may enhance immunity by stimulating cytokine secretion by leukocytes. To assess whether…”
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Experimental Murine IgA Nephropathy following Passive Administration of Vomitoxin-induced IgA Monoclonal Antibodies by Yan, D, Rumbeiha, W.K, Pestka, J.J

“…Oral exposure of mice to vomitoxin (VT) induces elevated levels of serum IgA, circulating IgA immune complexes (IgA-IC), mesangial IgA deposition and…”
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Effects of ingestion of yogurts containing Bifidobacterium and Lactobacillus acidophilus on spleen and Peyer's patch lymphocyte populations in the mouse by Pestka, J J, Ha, C L, Warner, R W, Lee, J H, Ustunol, Z

“…Certain probiotic lactic acid bacteria have been reported to improve immune system function. Here, the effects of ingesting yogurts on lymphocyte populations…”
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Effects of vomitoxin (Deoxynivalenol) and cycloheximide on IL-2, 4, 5 and 6 secretion and mRNA levels in murine CD4 + cells by Azcona-Olivera, J.I., Ouyang, Y.-L., Warner, R.L., Linz, J.E., Pestka, J.J.

“…The effects of continuous in vitro exposure to the trichothecene, vomitoxin (VT) or another protein synthesis inhibitor, cycloheximide (CHX), on interleukin…”
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Dysregulation of IgA production and IgA nephropathy induced by the trichothecene vomitoxin by Pestka, J J, Moorman, M A, Warner, R L

“…The effect of dietary exposure to vomitoxin on serum immunoglobulin A (IgA) was evaluated in the B6C3F1 mouse. Levels of serum IgA were elevated maximally in…”
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Effects of yogurt ingestion on mucosal and systemic cytokine gene expression in the mouse by Ha, C L, Lee, J H, Zhou, H R, Ustunol, Z, Pestka, J J

“…To assess the potential for ingestion of yogurt to modulate immunity, its effects on basal gene expression of cytokines in systemic and mucosal sites were…”
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Vomitoxin-induced dysregulation of serum IgA, IgM and IgG reactive with gut bacterial and self antigens by Rasooly, L, Pestka, J J

“…The effect of dietary vomitoxin exposure on immunoglobulins that react with naturally occurring gut bacterial and self antigens was assessed in the B6C3F1…”
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Effects of 8-week exposure of the B6C3F1 mouse to dietary deoxynivalenol (vomitoxin) and zearalenone by Forsell, J H, Witt, M F, Tai, J H, Jensen, R, Pestka, J J

“…Weanling female B6C3F1 mice were fed semi-purified diets containing 0, 0.5, 2.0, 5.0, 10.0 or 25.0 ppm (mg/kg) deoxynivalenol (DON) over 8 wk and were assessed…”
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Suppression of immune response in the B6C3F1 mouse after dietary exposure to the Fusarium mycotoxins deoxynivalenol (vomitoxin) and zearalenone by Pestka, J J, Tai, J H, Witt, M F, Dixon, D E, Forsell, J H

“…The effect that dietary exposure to the naturally-occurring Fusarium graminearum toxins deoxynivalenol (DON) and zearalenone (ZEA) may have on immune function…”
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Comparison of acute toxicities of deoxynivalenol (vomitoxin) and 15-acetyldeoxynivalenol in the B6C3F1 mouse by Forsell, J H, Jensen, R, Tai, J H, Witt, M, Lin, W S, Pestka, J J

“…The acute toxic effects of deoxynivalenol (DON) and 15-acetyldeoxynivalenol (15-ADON) were compared in the B6C3F1 female mouse after oral and intraperitoneal…”
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Transformation of Aspergillus parasiticus with a homologous gene (pyrG) involved in pyrimidine biosynthesis by Skory, C.D. (Michigan State University, East Lansing, MI), Horng, J.S, Pestka, J.J, Linz, J.E

“…The lack of efficient transformation methods for aflatoxigenic Aspergillus parasiticus has been a major constraint for the study of aflatoxin biosynthesis at…”
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Elevated membrane IgA+ and CD4+ (T helper) populations in murine Peyer's patch and splenic lymphocytes during dietary administration of the trichothecene vomitoxin (deoxynivalenol) by Pestka, J J, Dong, W, Warner, R L, Rasooly, L, Bondy, G S, Brooks, K H

“…Recent investigations indicate that dietary exposure to the trichothecene vomitoxin increases total and antigen-specific serum immunoglobulin A (IgA) and…”
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