Search Results - "Peschke, Theo"

Self‐Assembling All‐Enzyme Hydrogels for Flow Biocatalysis by Peschke, Theo, Bitterwolf, Patrick, Gallus, Sabrina, Hu, Yong, Oelschlaeger, Claude, Willenbacher, Norbert, Rabe, Kersten S., Niemeyer, Christof M.

“…Continuous flow biocatalysis is an emerging field of industrial biotechnology that uses enzymes immobilized in flow channels for the production of value‐added…”
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Evolution of Biocatalysis at Novartis over the last 40 Years by Siirola, Elina, Eggimann, Fabian, Moore, Charles, Schroer, Kirsten, Vargas, Alexandra, Peschke, Theo, Schlama, Thierry, Snajdrova, Radka

“…The fortieth anniversary of biocatalysis started at Ciba-Geigy and later at Novartis is a great time to pause and reflect on development of science and…”
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Pharmaceutical industry perspectives on flow chemocatalysis and biocatalysis by Leemans Martin, Laura, Peschke, Theo, Venturoni, Francesco, Mostarda, Serena

“…In response to a growing demand for more sustainable and cost-effective synthetic processes, the pharmaceutical industry is increasingly relying on continuous…”
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Self-Immobilizing Biocatalysts Maximize Space–Time Yields in Flow Reactors by Theo Peschke, Patrick Bitterwolf, Silla Hansen, Jannis Gasmi, Kersten S. Rabe, Christof M. Niemeyer

“…Maximizing space⁻time yields (STY) of biocatalytic flow processes is essential for the establishment of a circular biobased economy. We present a comparative…”
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Orthogonal Surface Tags for Whole‐Cell Biocatalysis by Peschke, Theo, Rabe, Kersten S., Niemeyer, Christof M.

“…We herein describe the engineering of E. coli strains that display orthogonal tags for immobilization on their surface and overexpress a functional…”
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Self-Immobilizing Fusion Enzymes for Compartmentalized Biocatalysis by Peschke, Theo, Skoupi, Marc, Burgahn, Teresa, Gallus, Sabrina, Ahmed, Ishtiaq, Rabe, Kersten S, Niemeyer, Christof M

“…The establishment of microfluidic enzyme cascades is a topical field of research and development, which is currently hampered by the lack of methodologies for…”
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Surface Display of Complex Enzymes by in Situ SpyCatcher‐SpyTag Interaction by Gallus, Sabrina, Peschke, Theo, Paulsen, Malte, Burgahn, Teresa, Niemeyer, Christof M., Rabe, Kersten S.

“…The display of complex proteins on the surface of cells is of great importance for protein engineering and other fields of biotechnology. Herein, we describe a…”
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Self‐Immobilizing Oxidoreductases for Flow Biocatalysis in Miniaturized Packed‐Bed Reactors by Peschke, Theo, Bitterwolf, Patrick, Rabe, Kersten S., Niemeyer, Christof M.

“…The industrial implementation of enzymes in flow biocatalysis microreactors is expected to be essential for the emergence of a bio‐based circular economy…”
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Valency engineering of monomeric enzymes for self-assembling biocatalytic hydrogels by Bitterwolf, Patrick, Gallus, Sabrina, Peschke, Theo, Mittmann, Esther, Oelschlaeger, Claude, Willenbacher, Norbert, Rabe, Kersten S, Niemeyer, Christof M

“…All-enzyme hydrogels are efficient reagents for continuous flow biocatalysis. These materials can be obtained by self-assembly of two oligomeric enzymes,…”
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Biocatalytic assembly of chemically modified oligonucleotides by Mann, Greg, Stanger, Frédéric V., Peschke, Theo, Schroer, Kirsten, Trung, Nhat Quang Nguyen, Burrer, Nathalie, Grassinger, Franziska, Piccioni, Lorenzo, Erdogan, Oemer, Heimburger, Jeremy, Koehl, Hervé, Ertle, Heike, Denay, Regis, Dreier, Philippe, Schlama, Thierry

“…[Display omitted] With renewed interest in therapeutic oligonucleotides, and at the same time the pharmaceutical industry set itself ambitious sustainability…”
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Cover Picture: Self‐Assembling All‐Enzyme Hydrogels for Flow Biocatalysis (Angew. Chem. Int. Ed. 52/2018) by Peschke, Theo, Bitterwolf, Patrick, Gallus, Sabrina, Hu, Yong, Oelschlaeger, Claude, Willenbacher, Norbert, Rabe, Kersten S., Niemeyer, Christof M.

“…The next wave of biocatalysis will be enabled by machine‐assisted flow processes that require tailor‐made materials to achieve efficient product conversion. In…”
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Valency engineering of monomeric enzymes for self-assembling biocatalytic hydrogels† †Electronic supplementary information (ESI) available: Contains details about plasmid construction, protein expression, DLS measurements, hydrogel preparation, MPT measurements, microreactor preparation, synthesis of reduced methylketones, chiral HPLC analysis, determination of enzyme activities, microfluidic setups and product purification conducted during this study. See DOI: 10.1039/c9sc04074a by Bitterwolf, Patrick, Gallus, Sabrina, Peschke, Theo, Mittmann, Esther, Oelschlaeger, Claude, Willenbacher, Norbert, Rabe, Kersten S., Niemeyer, Christof M.

“…All-enzyme hydrogels are efficient reagents for continuous flow biocatalysis. All-enzyme hydrogels are efficient reagents for continuous flow biocatalysis…”
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Machine-assisted cultivation and analysis of biofilms by Hansen, Silla H., Kabbeck, Tobias, Radtke, Carsten P., Krause, Susanne, Krolitzki, Eva, Peschke, Theo, Gasmi, Jannis, Rabe, Kersten S., Wagner, Michael, Horn, Harald, Hubbuch, Jürgen, Gescher, Johannes, Niemeyer, Christof M.

“…Biofilms are the natural form of life of the majority of microorganisms. These multispecies consortia are intensively studied not only for their effects on…”
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Chemoenzymatic Synthesis of O‐Containing Heterocycles from α‐Diazo Esters by Mittmann, Esther, Hu, Yuling, Peschke, Theo, Rabe, Kersten S., Niemeyer, Christof M., Bräse, Stefan

“…The synergy of biocatalysis and transition metal catalysis is rapidly moving forward, providing increasingly effective workflows in chemical synthesis. Here we…”
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Orthogonale Oberflächenmarkierungen für die Ganzzellkatalyse by Peschke, Theo, Rabe, Kersten S., Niemeyer, Christof M.

“…Wir beschreiben die Entwicklung von E.coli‐Stämmen, die einerseits auf ihrer Oberfläche orthogonale Markierungen präsentieren und andererseits einen…”
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Titelbild: Self‐Assembling All‐Enzyme Hydrogels for Flow Biocatalysis (Angew. Chem. 52/2018) by Peschke, Theo, Bitterwolf, Patrick, Gallus, Sabrina, Hu, Yong, Oelschlaeger, Claude, Willenbacher, Norbert, Rabe, Kersten S., Niemeyer, Christof M.

“…Die nächste Welle der Biokatalyse wird durch maschinengestützte Strömungsprozesse ermöglicht werden, die maßgeschneiderte Materialien benötigen, um eine…”
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Self‐Assembling All‐Enzyme Hydrogels for Flow Biocatalysis by Peschke, Theo, Bitterwolf, Patrick, Gallus, Sabrina, Hu, Yong, Oelschlaeger, Claude, Willenbacher, Norbert, Rabe, Kersten S., Niemeyer, Christof M.

“…Continuous flow biocatalysis is an emerging field of industrial biotechnology that uses enzymes immobilized in flow channels for the production of value‐added…”
Get full text

Orthogonale Oberflächenmarkierungen fur die Ganzzellkatalyse by Peschke, Theo, Rabe, Kersten S, Niemeyer, Christof M

“…Wir beschreiben die Entwicklung von E.coli-Stämmen, die einerseits auf ihrer Oberfläche orthogonale Markierungen präsentieren und andererseits einen…”
Get full text