Search Results - "Pesch, Vincent"
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1
Exosomal profiling should be used to monitor disease activity in MS patients: No
Published in Multiple sclerosis (01-09-2023)Get full text
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Paramagnetic Rim Lesions are Specific to Multiple Sclerosis: An International Multicenter 3T MRI Study
Published in Annals of neurology (01-11-2020)“…In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on magnetic resonance imaging by their paramagnetic rims, and…”
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3
Immune-mediated neurological syndromes in SARS-CoV-2-infected patients
Published in Journal of neurology (01-03-2021)“…Background Evidence of immune-mediated neurological syndromes associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection is…”
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Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis
Published in Journal of neurology, neurosurgery and psychiatry (01-04-2019)“…ObjectiveOral immunotherapies have become a standard treatment in relapsing-remitting multiple sclerosis. Direct comparison of their effect on relapse and…”
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IL-22, GM-CSF and IL-17 in peripheral CD4+ T cell subpopulations during multiple sclerosis relapses and remission. Impact of corticosteroid therapy
Published in PloS one (01-03-2017)“…Multiple sclerosis (MS) is thought to be a Th17-mediated dysimmune disease of the central nervous system. However, recent publications have questioned the…”
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Cutaneous diseases related to a hyperactive T-cell response in ocrelizumab-treated multiple sclerosis patients
Published in Journal of neurology (01-11-2021)Get full text
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7
Prophylactic treatment against GM‐CSF, but not IL‐17, abolishes relapses in a chronic murine model of multiple sclerosis
Published in European journal of immunology (01-11-2018)“…The pathogenic role of IL‐17 and GM‐CSF has been unravelled in experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS)…”
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The central vein sign in multiple sclerosis patients with vascular comorbidities
Published in Multiple sclerosis (01-06-2021)“…Background: The central vein sign (CVS) is an imaging biomarker able to differentiate multiple sclerosis (MS) from other conditions causing similar appearance…”
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Enlarged perivascular spaces are associated with brain microangiopathy and aging in multiple sclerosis
Published in Multiple sclerosis (01-07-2024)“…Background: Growing evidence links brain-MRI enlarged perivascular spaces (EPVS) and multiple sclerosis (MS), but their role remains unclear. Objective: This…”
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Variability of the response to immunotherapy among subgroups of patients with multiple sclerosis
Published in European journal of neurology (01-04-2023)“…Background and purpose This study assessed the effect of patient characteristics on the response to disease‐modifying therapy (DMT) in multiple sclerosis (MS)…”
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International consensus on quality standards for brain health-focused care in multiple sclerosis
Published in Multiple sclerosis (01-11-2019)“…Background: Time matters in multiple sclerosis (MS). Irreversible neural damage and cell loss occur from disease onset. The MS community has endorsed a…”
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Mechanism of Cellular Formation and In Vivo Seeding Effects of Hexameric β-Amyloid Assemblies
Published in Molecular neurobiology (01-12-2021)“…The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer’s disease (AD). However, intermediate soluble…”
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Comparative effectiveness of cladribine tablets versus other oral disease-modifying treatments for multiple sclerosis: Results from MSBase registry
Published in Multiple sclerosis (01-02-2023)“…Background: Effectiveness of cladribine tablets, an oral disease-modifying treatment (DMT) for multiple sclerosis (MS), was established in clinical trials and…”
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Prediction of relapse activity when switching to cladribine for multiple sclerosis
Published in Multiple sclerosis (01-01-2023)“…Background: Patients with relapsing–remitting multiple sclerosis commonly switch between disease-modifying therapies (DMTs). Identifying predictors of relapse…”
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Higher latitude is significantly associated with an earlier age of disease onset in multiple sclerosis
Published in Journal of neurology, neurosurgery and psychiatry (01-12-2016)“…BackgroundAge at onset (AAO) in multiple sclerosis (MS) is an important marker of disease severity and may have prognostic significance. Understanding what…”
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Confirmed disability progression as a marker of permanent disability in multiple sclerosis
Published in European journal of neurology (01-08-2022)“…Background and purpose The prevention of disability over the long term is the main treatment goal in multiple sclerosis (MS); however, randomized clinical…”
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Simultaneous bilateral optic neuropathy and myelitis revealing paraneoplastic neurological syndrome associated with multiple onconeuronal antibodies
Published in Multiple sclerosis and related disorders (01-04-2021)“…Paraneoplastic neurological syndromes (PNS) are immune-mediated complications of cancer associated with a broad spectrum of clinical manifestations. Optic…”
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Prediction of multiple sclerosis outcomes when switching to ocrelizumab
Published in Multiple sclerosis (01-05-2022)“…Background: Increasingly, people with relapsing-remitting multiple sclerosis (RRMS) are switched to highly effective disease-modifying therapies (DMTs) such as…”
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Molecular Mechanisms of Immunosenescene and Inflammaging: Relevance to the Immunopathogenesis and Treatment of Multiple Sclerosis
Published in Frontiers in neurology (25-02-2022)“…Aging is characterized, amongst other features, by a complex process of cellular senescence involving both innate and adaptive immunity, called…”
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A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology
Published in Frontiers in neurology (30-05-2018)“…The current inability of clinical criteria to accurately identify the "at-risk group" for Amyotrophic Lateral Sclerosis (ALS) development as well as its…”
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