Search Results - "Pervinder, Sagoo"

CD200 Expression Marks a Population of Quiescent Limbal Epithelial Stem Cells with Holoclone Forming Ability by Bojic, Sanja, Hallam, Dean, Alcada, Nuno, Ghareeb, Ali, Queen, Rachel, Pervinder, Sagoo, Buck, Harley, Amitai Lange, Aya, Figueiredo, Gustavo, Rooney, Paul, Stojkovic, Miodrag, Shortt, Alex, Figueiredo, Francisco C., Lako, Majlinda

“…One of the main challenges in limbal stem cell (LSC) biology and transplantation is the lack of definitive cell surface markers which can be used to identify…”
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Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ T regulatory cell subpopulations by Scottà, Cristiano, Esposito, Marianna, Fazekasova, Henrieta, Fanelli, Giorgia, Edozie, Francis C, Ali, Niwa, Xiao, Fang, Peakman, Mark, Afzali, Behdad, Sagoo, Pervinder, Lechler, Robert I, Lombardi, Giovanna

“…Adoptive transfer of ex vivo expanded CD4(+)CD25(+)FOXP3(+) regulatory T cells is a successful therapy for autoimmune diseases and transplant rejection in…”
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Dendritic Cells as a Tool to Induce Transplantation Tolerance: Obstacles and Opportunities by VAN KOOTEN, Cees, LOMBARDI, Giovanna, GELDERMAN, Kyra A, SAGOO, Pervinder, BUCKLAND, Matthew, LECHLER, Robert, CUTURI, Maria Cristina

“…Dendritic cells are the key component to regulate and coordinate adaptive immune responses, including tolerance. This overview will briefly summarize different…”
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Monitoring of in vivo function of superparamagnetic iron oxide labelled murine dendritic cells during anti-tumour vaccination by Tavaré, Richard, Sagoo, Pervinder, Varama, Gopal, Tanriver, Yakup, Warely, Alice, Diebold, Sandra S, Southworth, Richard, Schaeffter, Tobias, Lechler, Robert I, Razavi, Reza, Lombardi, Giovanna, Mullen, Gregory E D

“…Dendritic cells (DCs) generated in vitro to present tumour antigens have been injected in cancer patients to boost in vivo anti-tumour immune responses. This…”
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Inflammatory Cytokines Induce Apoptosis of Corneal Endothelium through Nitric Oxide by Sagoo, Pervinder, Chan, Giulia, Larkin, Daniel F. P, George, Andrew J. T

“…Proinflammatory cytokines are integral components of the allogeneic response to a corneal transplant and contribute to the pathogenesis of graft failure that…”
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The transformative potential of HSC gene therapy as a genetic medicine by Sagoo, Pervinder, Gaspar, H. Bobby

“…Hematopoietic stem cells (HSCs) are precursor cells that give rise to blood, immune and tissue-resident progeny in humans. Their position at the starting point…”
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The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation by Michonneau, David, Sagoo, Pervinder, Breart, Béatrice, Garcia, Zacarias, Celli, Susanna, Bousso, Philippe

“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT), a curative treatment for hematologic malignancies, relies on donor cytotoxic T lymphocyte…”
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Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells by Sagoo, Pervinder, Ali, Niwa, Garg, Garima, Nestle, Frank O, Lechler, Robert I, Lombardi, Giovanna

“…Graft rejection by the immune system is a major cause of transplant failure. Lifelong immunosuppression decreases the incidence of graft rejection; however,…”
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In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity by Sagoo, Pervinder, Garcia, Zacarias, Breart, Beatrice, Lemaître, Fabrice, Michonneau, David, Albert, Matthew L, Levy, Yves, Bousso, Philippe

“…Visualization and tracking of inflammasome activity and ASC speck formation in vivo following viral infection. The inflammasome is activated in response to a…”
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HEMATOPOIETIC STEM CELL GENE THERAPY AS A NOVEL THERAPEUTIC APPROACH FOR SEVERE CROHN’S DISEASE ASSOCIATED WITH NOD2-DEFICIENCY by Enjalbert, Florence, Del Mar Masdeu, Maria, Zabinski, Tomasz, Narean, Janakan Sam, Whiting, Christopher, Elavazhagan, Saranya, Luiz, Ana, Du, Lily, Pennucci, Valentina, Cattoni, Marina, Heal, Paul, Recchi, Chiara, Gaspar, Bobby, Mavilio, Fulvio, Sagoo, Pervinder

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HEMATOPOIETIC STEM CELL GENE THERAPY AS A NOVEL THERAPEUTIC APPROACH FOR SEVERE CROHN’S DISEASE ASSOCIATED WITH NOD2-DEFICIENCY by Enjalbert, Florence, Masdeu, Maria Del Mar, Zabinski, Tomasz, Narean, Janakan Sam, Whiting, Christopher, Elavazhagan, Saranya, Luiz, Ana, Du, Lily, Pennucci, Valentina, Cattoni, Marina, Heal, Paul, Recchi, Chiara, Gaspar, Bobby, Mavilio, Fulvio, Sagoo, Pervinder

“…Pathogenic variants of the NOD2 (nucleotide-binding oligomerization domain containing protein 2) gene demonstrate the strongest genetic association to Crohn’s…”
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Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans by Sagoo, Pervinder, Perucha, Esperanza, Sawitzki, Birgit, Tomiuk, Stefan, Stephens, David A, Miqueu, Patrick, Chapman, Stephanie, Craciun, Ligia, Sergeant, Ruhena, Brouard, Sophie, Rovis, Flavia, Jimenez, Elvira, Ballow, Amany, Giral, Magali, Rebollo-Mesa, Irene, Le Moine, Alain, Braudeau, Cecile, Hilton, Rachel, Gerstmayer, Bernhard, Bourcier, Katarzyna, Sharif, Adnan, Krajewska, Magdalena, Lord, Graham M, Roberts, Ian, Goldman, Michel, Wood, Kathryn J, Newell, Kenneth, Seyfert-Margolis, Vicki, Warrens, Anthony N, Janssen, Uwe, Volk, Hans-Dieter, Soulillou, Jean-Paul, Hernandez-Fuentes, Maria P, Lechler, Robert I

“…Identifying transplant recipients in whom immunological tolerance is established or is developing would allow an individually tailored approach to their…”
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Expression of complement components, receptors and regulators by human dendritic cells by Li, Ke, Fazekasova, Henrieta, Wang, Naiyin, Sagoo, Pervinder, Peng, Qi, Khamri, Wafa, Gomes, Chantelle, Sacks, Steven H., Lombardi, Giovanna, Zhou, Wuding

“…Integration of innate and adaptive arms of the immune response at a cellular and molecular level appears to be fundamental to the development of powerful…”
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Tolerogenic Donor-Derived Dendritic Cells Risk Sensitization In Vivo owing to Processing and Presentation by Recipient APCs by Smyth, Lesley A, Ratnasothy, Kulachelvy, Moreau, Aurelie, Alcock, Sally, Sagoo, Pervinder, Meader, Lucy, Tanriver, Yakup, Buckland, Matthew, Lechler, Robert, Lombardi, Giovanna

“…Modification of allogeneic dendritic cells (DCs) through drug treatment results in DCs with in vitro hallmarks of tolerogenicity. Despite these observations,…”
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Relevance of regulatory T cell promotion of donor-specific tolerance in solid organ transplantation by Sagoo, Pervinder, Lombardi, Giovanna, Lechler, Robert I

“…Current clinical strategies to control the alloimmune response after transplantation do not fully prevent induction of the immunological processes which lead…”
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Regulatory T cells as therapeutic cells by Sagoo, Pervinder, Lombardi, Giovanna, Lechler, Robert I

“…Although a plethora of data indicate the importance of regulatory T cells (Tregs) in experimental and clinical transplantation, are we any closer to seeing…”
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Tu1723 HEMATOPOIETIC STEM CELL GENE THERAPY AS A TREATMENT FOR SEVERE CROHN'S DISEASE ASSOCIATED WITH PATHOGENIC NOD2 GENETIC VARIANTS by Enjalbert, Florence, del MarMasdeu, Maria, Zabinski, Tomasz, Narean, Janakan Sam, Whiting, Christopher, Elavazhagan, Saranya, Luiz, Ana P., Du, Lily, Pennucci, Valentina, Cattoni, Marina, Recchi, Chiara, Heal, Paul A., Gaspar, Bobby, Mavilio, Fulvio, Sagoo, Pervinder

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Adoptive regulatory T cell therapy: challenges in clinical transplantation by Safinia, Niloufar, Sagoo, Pervinder, Lechler, Robert, Lombardi, Giovanna

“…The identification and characterisation of regulatory T cells (Tregs) has recently opened up exciting opportunities for Treg cell therapy in transplantation…”
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Inhibition of NF-kappa B and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells by Tan, Peng H, Sagoo, Pervinder, Chan, Cliburn, Yates, John B, Campbell, Jamie, Beutelspacher, Sven C, Foxwell, Brian M J, Lombardi, Giovanna, George, Andrew J T

“…Dendritic cells (DCs) are central to T cell immunity, and many strategies have been used to manipulate DCs to modify immune responses. We investigated the…”
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Monitoring the efficacy of dendritic cell vaccination by early detection of 99mTc‐HMPAO‐labelled CD4+ T cells by Sharif‐Paghaleh, Ehsan, Leech, John, Sunassee, Kavitha, Ali, Niwa, Sagoo, Pervinder, Lechler, Robert I., Smyth, Lesley A., Lombardi, Giovanna, Mullen, Gregory E.

“…DC vaccines have been used to induce tumour‐specific cytotoxic T cells . However, this approach to cancer immunotherapy has had limited success. To be…”
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