Search Results - "Peruzzi, Daniela"

MMP11: A Novel Target Antigen for Cancer Immunotherapy by Peruzzi, Daniela, Mori, Federica, Conforti, Antonella, Lazzaro, Domenico, De Rinaldis, Emanuele, Ciliberto, Gennaro, La Monica, Nicola, Aurisicchio, Luigi

“…Purpose: Matrix metalloproteinases (MMP) are zinc-dependent endopeptidases that mediate numerous physiologic and pathologic processes, including matrix…”
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A Vaccine Targeting Telomerase Enhances Survival of Dogs Affected by B-cell Lymphoma by Peruzzi, Daniela, Gavazza, Alessandra, Mesiti, Giuseppe, Lubas, George, Scarselli, Elisa, Conforti, Antonella, Bendtsen, Claus, Ciliberto, Gennaro, La Monica, Nicola, Aurisicchio, Luigi

“…Canine cancers occur with an incidence similar to that of humans and share many features with human malignancies including histological appearance, tumor…”
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Nucleotide Sequence of the Kaposi Sarcoma-Associated Herpesvirus (HHV8) by Russo, James J., Bohenzky, Roy A., Chien, Ming-Cheng, Chen, Jing, Yan, Ming, Maddalena, Dawn, Parry, J. Preston, Peruzzi, Daniela, Edelman, Isidore S., Chang, Yuan, Moore, Patrick S.

“…The genome of the Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) was mapped with cosmid and phage genomic libraries from the BC-1 cell line. Its…”
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Treatment of Mammary Carcinomas in HER-2 Transgenic Mice through Combination of Genetic Vaccine and an Agonist of Toll-Like Receptor 9 by AURISICCHIO, Luigi, PERUZZI, Daniela, KANDIMALLA, Ekambar R, AGRAVVAL, Sudhir, CILIBERTO, Gennaro, LA MONICA, Nicola, CONFORTI, Antonella, DHARMAPURI, Sridhar, BIONDO, Antonella, GIAMPAOLI, Saverio, FRIDMAN, Arthur, BAGCHI, Ansu, WINKELMANN, Christopher T, GIBSON, Raymond

“…Purpose: Oligodeoxynucleotides containing unmethylated CpG dinucleotides induce innate and adaptive immunity through Toll-like receptor 9 (TLR9). In the…”
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Acute Leukemia with Promyelocytic Features in PML/RARα Transgenic Mice by He, Li-Zhen, Tribioli, Carla, Rivi, Roberta, Peruzzi, Daniela, Pelicci, Pier Giuseppe, Soares, Vera, Cattoretti, Giorgio, Pandolfi, Pier Paolo

“…Acute promyelocytic leukemia (APL) is associated with reciprocal chromosomal translocations involving the retinoic acid receptor α (RARα ) locus on chromosome…”
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An efficient T-cell epitope discovery strategy using in silico prediction and the iTopia assay platform by Fridman, Arthur, Finnefrock, Adam C., Peruzzi, Daniela, Pak, Irene, La Monica, Nicola, Bagchi, Ansuman, Casimiro, Danilo R., Ciliberto, Gennaro, Aurisicchio, Luigi

“…Functional T-cell epitope discovery is a key process for the development of novel immunotherapies, particularly for cancer immunology. In silico epitope…”
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A therapeutic cancer vaccine targeting carcinoembryonic antigen in intestinal carcinomas by Mori, Federica, Giannetti, Patrizia, Peruzzi, Daniela, Lazzaro, Domenico, Giampaoli, Saverio, Kaufman, Howard L, Ciliberto, Gennaro, La Monica, Nicola, Aurisicchio, Luigi

“…A genetic vaccine platform based on DNA electroporation (DNA-EP) and adenovirus (Ad) was used to generate immune response against human carcinoembryonic…”
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Immunogenicity and therapeutic efficacy of a dual-component genetic cancer vaccine cotargeting carcinoembryonic antigen and HER2/neu in preclinical models by Aurisicchio, Luigi, Peruzzi, Daniela, Koo, Gloria, Wei, Wei-Zen, La Monica, Nicola, Ciliberto, Gennaro

“…Several cancer vaccine efforts have been directed to simultaneously cotarget multiple tumor antigens, with the intent to achieve broader immune responses and…”
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Safety and efficacy of a genetic vaccine targeting telomerase plus chemotherapy for the therapy of canine B-cell lymphoma by Gavazza, Alessandra, Lubas, George, Fridman, Arthur, Peruzzi, Daniela, Impellizeri, Joseph A, Luberto, Laura, Marra, Emanuele, Roscilli, Giuseppe, Ciliberto, Gennaro, Aurisicchio, Luigi

“…Client-owned pet dogs represent exceptional translational models for advancement of cancer research because they reflect the complex heterogeneity observed in…”
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Endotracheal tube-induced sore throat pain and inflammation is coupled to the release of mitochondrial DNA by Puyo, Carlos A, Peruzzi, Daniela, Earhart, Alexander, Roller, Evan, Karanikolas, Menelaos, Kollef, Marin H, Krupnick, Alexander S, Kreisel, Daniel, Ibrahim, Mohsen, Gelman, Andrew E

“…In the absence of infection, the pathophysiology of endotracheal tube-induced sore throat pain is unclear. Activated neutrophils release elastase, reactive…”
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Telomerase and HER-2/ neu as targets of genetic cancer vaccines in dogs by Peruzzi, Daniela, Mesiti, Giuseppe, Ciliberto, Gennaro, La Monica, Nicola, Aurisicchio, Luigi

“…Abstract Pet dogs represent a valuable pre-clinical model to assess the efficacy of oncology drugs. Additionally, canine cancers occur with an incidence…”
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Engineered adenovirus serotypes for overcoming anti-vector immunity by Dharmapuri, Sridhar, Peruzzi, Daniela, Aurisicchio, Luigi

“…Adenovirus (Ad)-based gene transfer has been successfully utilised in gene therapy and vaccine applications. To date, an increasing number of human clinical…”
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Abstract 291: Targeting the stroma to hit the tumor: MMP11 as a novel target for cancer immunotherapy by Luberto, Laura, Mancini, Rita, Di Napoli, Arianna, Peruzzi, Daniela, Mori, Federica, Roscilli, Giuseppe, Marra, Emanuele, Cappelletti, Manuela, Ciliberto, Gennaro, Aurisicchio, Luigi

“…Abstract Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that mediate a number of physiological and pathological processes, such as matrix…”
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A novel Chimpanzee serotype-based adenoviral vector as delivery tool for cancer vaccines by Peruzzi, Daniela, Dharmapuri, Sridhar, Cirillo, Agostino, Bruni, Bruno Ercole, Nicosia, Alfredo, Cortese, Riccardo, Colloca, Stefano, Ciliberto, Gennaro, La Monica, Nicola, Aurisicchio, Luigi

“…Abstract The use of adenovirus (Ad) as vaccine vectors is hindered by pre-existing immunity to human Ads in most of the human population. In order to overcome…”
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Abstract B19: Fetal lung adenocarcinoma: Characterization of primary cell culture and in vitro drug response by Menna, Cecilia, Ibrahim, Mohsen, Peruzzi, Daniela, Pacini, Luca, Ciancamerla, Michela, Calogero, Antonella, Rendina, Erino Angelo

“…Abstract Purpose: Fetal lung adenocarcinoma (FLAC) is an extremely rare subtype of pulmonary adenocarcinoma estimated to be the 0.5% of all lung cancers…”
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Abstract 2846: Safety and efficacy of a genetic vaccine targeting telomerase plus chemotherapy for the therapy of canine B-cell lymphoma by Gavazza, Alessandra, Lubas, George, Fridman, Arthur, Peruzzi, Daniela, Impellizeri, Joseph A., Luberto, Laura, Marra, Emanuele, Roscilli, Giuseppe, Ciliberto, Gennaro, Aurisicchio, Luigi

“…Abstract Background: We have recently shown that a genetic vaccine targeting dog telomerase (dTERT) and based on Ad/DNA-EGT technology can induce strong…”
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Distinct interactions of PML-RARα and PLZF-RARα with co-repressors determine differential responses to RA in APL by He, Li-Zhen, Guidez, Fabien, Tribioli, Carla, Peruzzi, Daniela, Ruthardt, Martin, Zelent, Arthur, Pandolfi, Pier Paolo

“…Acute promyelocytic leukaemia (APL), associated with chromosomal translocations involving the retinoic acid receptor alpha gene (RARA) and the PML gene, is…”
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A Role for Nuclear Phospholipase Cβ1 in Cell Cycle Control by Faenza, Irene, Matteucci, Alessandro, Manzoli, Lucia, Billi, Anna Maria, Aluigi, Michela, Peruzzi, Daniela, Vitale, Marco, Castorina, Sergio, Suh, Pann-Ghill, Cocco, Lucio

“…Phosphoinositide signaling resides in the nucleus, and among the enzymes of the cycle, phospholipase C (PLC) appears as the key element both in Saccharomyces…”
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A TLR9 agonist enhances therapeutic effects of telomerase genetic vaccine by Conforti, Antonella, Cipriani, Barbara, Peruzzi, Daniela, Dharmapuri, Sridhar, Kandimalla, Ekambar R, Agrawal, Sudhir, Mori, Federica, Ciliberto, Gennaro, La Monica, Nicola, Aurisicchio, Luigi

“…Abstract The telomerase reverse transcriptase (TERT) is an attractive target for cancer vaccination because its expression is reactivated in most tumors. In…”
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Coadministration of Telomerase Genetic Vaccine and a Novel TLR9 Agonist in Nonhuman Primates by Dharmapuri, Sridhar, Peruzzi, Daniela, Mennuni, Carmela, Calvaruso, Francesco, Giampaoli, Saverio, Barbato, Gaetano, Kandimalla, Ekambar R, Agrawal, Sudhir, Scarselli, Elisa, Mesiti, Giuseppe, Ciliberto, Gennaro, La Monica, Nicola, Aurisicchio, Luigi

“…The human telomerase reverse transcriptase (hTERT) is an attractive target for human cancer vaccination because its expression is reactivated in most human…”
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