Search Results - "Persyn, Eva"
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T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells
Published in Frontiers in immunology (24-09-2021)“…T-bet and Eomes are transcription factors that are known to be important in maturation and function of murine natural killer (NK) cells. Reduced T-BET and…”
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T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells
Published in Frontiers in immunology (18-10-2022)“…Type 3 innate lymphoid cells (ILC3s) are characterized by RORγt expression and they produce IL-22 upon activation. ILC3s play a role in maintenance of barrier…”
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TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality
Published in International journal of molecular sciences (01-10-2022)“…The ability of natural killer (NK) cells to kill tumor cells without prior sensitization makes them a rising player in immunotherapy. Increased understanding…”
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The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency
Published in eLife (06-07-2022)“…Natural killer (NK) cells are innate lymphocytes that eliminate virus-infected and cancer cells by cytotoxicity and cytokine secretion. In addition to…”
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IRF2 is required for development and functional maturation of human NK cells
Published in Frontiers in immunology (05-12-2022)“…Natural killer (NK) cells are cytotoxic and cytokine-producing lymphocytes that play an important role in the first line of defense against malignant or…”
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The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation
Published in Blood (16-07-2020)“…Natural killer (NK) cells are important in the immune defense against tumor cells and pathogens, and they regulate other immune cells by cytokine secretion…”
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