Search Results - "Persing, David H."

Laboratory Diagnosis of COVID-19: Current Issues and Challenges by Tang, Yi-Wei, Schmitz, Jonathan E, Persing, David H, Stratton, Charles W

“…The COVID-19 outbreak has had a major impact on clinical microbiology laboratories in the past several months. This commentary covers current issues and…”
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Rapid Molecular Detection of Tuberculosis and Rifampin Resistance by Boehme, Catharina C, Nabeta, Pamela, Hillemann, Doris, Nicol, Mark P, Shenai, Shubhada, Krapp, Fiorella, Allen, Jenny, Tahirli, Rasim, Blakemore, Robert, Rustomjee, Roxana, Milovic, Ana, Jones, Martin, O'Brien, Sean M, Persing, David H, Ruesch-Gerdes, Sabine, Gotuzzo, Eduardo, Rodrigues, Camilla, Alland, David, Perkins, Mark D

“…Samples from patients with suspected TB were assayed for TB and drug resistance with several different techniques. An automated molecular test showed a…”
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Multicenter Evaluation of the Cepheid Xpert Xpress SARS-CoV-2 Test by Loeffelholz, Michael J, Alland, David, Butler-Wu, Susan M, Pandey, Utsav, Perno, Carlo Frederico, Nava, Alice, Carroll, Karen C, Mostafa, Heba, Davies, Emma, McEwan, Ashley, Rakeman, Jennifer L, Fowler, Randal C, Pawlotsky, Jean-Michel, Fourati, Slim, Banik, Sukalyani, Banada, Padmapriya P, Swaminathan, Shobha, Chakravorty, Soumitesh, Kwiatkowski, Robert W, Chu, Victor C, Kop, JoAnn, Gaur, Rajiv, Sin, Mandy L Y, Nguyen, Duy, Singh, Simranjit, Zhang, Na, Persing, David H

“…Nucleic acid amplification tests (NAATs) are the primary means of identifying acute infections caused by severe acute respiratory syndrome coronavirus 2…”
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Antimicrobial-Resistant Strains of Clostridium difficile from North America by TENOVER, Fred C, TICKLER, Isabella A, PERSING, David H

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Rapid Detection of Mycobacterium tuberculosis and Rifampin Resistance by Use of On-Demand, Near-Patient Technology by HELB, Danica, JONES, Martin, SAFI, Hassan, BLAKEMORE, Robert, NGOC LAN, N. T, JONES-LOPEZ, Edward C, LEVI, Michael, BURDAY, Michele, AYAKAKA, Irene, MUGERWA, Roy D, MCMILLAN, Bill, WINN-DEEN, Emily, STORY, Elizabeth, CHRISTEL, Lee, DAILEY, Peter, PERKINS, Mark D, PERSING, David H, ALLAND, David, BOEHME, Catharina, WALLACE, Ellen, HO, Ken, KOP, Joann, OWENS, Michelle R, RODGERS, Richard, BANADA, Padmapriya

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Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis by Ma, Yuqian, Vilanova, David, Atalar, Kerem, Delfour, Olivier, Edgeworth, Jonathan, Ostermann, Marlies, Hernandez-Fuentes, Maria, Razafimahatratra, Sandrine, Michot, Bernard, Persing, David H, Ziegler, Ingrid, Törös, Bianca, Mölling, Paula, Olcén, Per, Beale, Richard, Lord, Graham M

“…Sepsis is a common cause of death in the intensive care unit with mortality up to 70% when accompanied by multiple organ dysfunction. Rapid diagnosis and the…”
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Strain Types and Antimicrobial Resistance Patterns of Clostridium difficile Isolates from the United States, 2011 to 2013 by TICKLER, Isabella A, GOERING, Richard V, WHITMORE, Joseph D, LYNN, Ashley N. W, PERSING, David H, TENOVER, Fred C

“…We determined the PCR ribotypes and antimicrobial susceptibility patterns of 508 toxigenic Clostridium difficile isolates collected between 2011 and 2013 from…”
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Detection of Colonization by Carbapenemase-Producing Gram-Negative Bacilli in Patients by Use of the Xpert MDRO Assay by Tenover, Fred C, Canton, Rafael, Kop, JoAnn, Chan, Ryan, Ryan, Jamie, Weir, Fred, Ruiz-Garbajosa, Patricia, LaBombardi, Vincent, Persing, David H

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Characterization of Nasal and Blood Culture Isolates of Methicillin-Resistant Staphylococcus aureus from Patients in United States Hospitals by TENOVER, Fred C, TICKLER, Isabella A, GOERING, Richard V, KREISWIRTH, Barry N, MEDIAVILLA, José R, PERSING, David H

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Impact of Strain Type on Detection of Toxigenic Clostridium difficile: Comparison of Molecular Diagnostic and Enzyme Immunoassay Approaches by Tenover, Fred C, Novak-Weekley, Susan, Woods, Christopher W, Peterson, Lance R, Davis, Thomas, Schreckenberger, Paul, Fang, Ferric C, Dascal, Andre, Gerding, Dale N, Nomura, Jim H, Goering, Richard V, Akerlund, Thomas, Weissfeld, Alice S, Baron, Ellen Jo, Wong, Edith, Marlowe, Elizabeth M, Whitmore, Joseph, Persing, David H

“…A multicenter clinical trial assessed the performance of the Cepheid Xpert C. difficile assay on stool specimens collected from patients suspected of having…”
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Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus by Pinsky, Benjamin A, Sahoo, Malaya K, Sandlund, Johanna, Kleman, Marika, Kulkarni, Medha, Grufman, Per, Nygren, Malin, Kwiatkowski, Robert, Baron, Ellen Jo, Tenover, Fred, Denison, Blake, Higuchi, Russell, Van Atta, Reuel, Beer, Neil Reginald, Carrillo, Alda Celena, Naraghi-Arani, Pejman, Mire, Chad E, Ranadheera, Charlene, Grolla, Allen, Lagerqvist, Nina, Persing, David H

“…The recently developed Xpert® Ebola Assay is a novel nucleic acid amplification test for simplified detection of Ebola virus (EBOV) in whole blood and buccal…”
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A novel blood-based assay for treatment monitoring of tuberculosis by Zimmer, Alexandra J, Schumacher, Samuel G, Södersten, Erik, Mantsoki, Anna, Wyss, Romain, Persing, David H, Banderby, Sara, Strömqvist Meuzelaar, Linda, Prieto, Jacqueline, Gnanashanmugam, Devasena, Khatri, Purvesh, Ongarello, Stefano, Ruhwald, Morten, Denkinger, Claudia M

“…A novel 3-gene host transcriptional signature (GBP5, DUSP3 and KLF2) has been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA…”
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Comparison of Strain Typing Results for Clostridium difficile Isolates from North America by TENOVER, Fred C, AKERLUND, Thomas, GERDING, Dale N, GOERING, Richard V, BOSTRÖM, Therése, JONSSON, Anna-Maria, WONG, Edith, WORTMAN, Alan T, PERSING, David H

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mRNA biomarker detection in liquid-based cytology: a new approach in the prevention of cervical cancer by del Pino, Marta, Svanholm-Barrie, Cecilia, Torné, Aureli, Marimon, Lorena, Gaber, Jina, Sagasta, Amaia, Persing, David H, Ordi, Jaume

“…Several high-risk human papillomavirus (HPV)-induced cell biomarkers have been proposed as possible candidates to identify patients harboring high-grade…”
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Blood-based host biomarker diagnostics in active case finding for pulmonary tuberculosis: A diagnostic case-control study by Moreira, Flora Martinez Figueira, Verma, Renu, Pereira dos Santos, Paulo Cesar, Leite, Alessandra, da Silva Santos, Andrea, de Araujo, Rafaele Carla Pivetta, da Silva, Bruna Oliveira, de Sá Queiroz, Júlio Henrique Ferreira, Persing, David H., Södersten, Erik, Gnanashanmugam, Devasena, Khatri, Purvesh, Croda, Julio, Andrews, Jason R.

“…There is a need to identify scalable tuberculosis screening strategies among high burden populations. The WHO has identified a non-sputum-based triage test as…”
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Novel Host Response-Based Diagnostics to Differentiate the Etiology of Fever in Patients Presenting to the Emergency Department by Atallah, Johnny, Ghebremichael, Musie, Timmer, Kyle D, Warren, Hailey M, Mallinger, Ella, Wallace, Ellen, Strouts, Fiona R, Persing, David H, Mansour, Michael K

“…Fever is a common presentation to urgent-care services and is linked to multiple disease processes. To rapidly determine the etiology of fever, improved…”
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Alternative processing of the U2 small nuclear RNA produces a 19-22nt fragment with relevance for the detection of non-small cell lung cancer in human serum by Mazières, Julien, Catherinne, Caroline, Delfour, Olivier, Gouin, Sandrine, Rouquette, Isabelle, Delisle, Marie-Bernadette, Prévot, Grégoire, Escamilla, Roger, Didier, Alain, Persing, David H, Bates, Mike, Michot, Bernard

“…RNU2 exists in two functional forms (RNU2-1 and RNU2-2) distinguishable by the presence of a unique 4-bases motif. Detailed investigation of datasets obtained…”
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A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease by Fort, Madeline M, Mozaffarian, Afsaneh, Stover, Axel G, Correia, Jean da Silva, Johnson, David A, Crane, R. Thomas, Ulevitch, Richard J, Persing, David H, Bielefeldt-Ohmann, Helle, Probst, Peter, Jeffery, Eric, Fling, Steven P, Hershberg, Robert M

“…Current evidence indicates that the chronic inflammation observed in the intestines of patients with inflammatory bowel disease is due to an aberrant immune…”
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Propionibacterium acnes Types I and II Represent Phylogenetically Distinct Groups by McDowell, Andrew, Valanne, Susanna, Ramage, Gordon, Tunney, Michael M, Glenn, Josephine V, McLorinan, Gregory C, Bhatia, Ajay, Maisonneuve, Jean-Francois, Lodes, Michael, Persing, David H, Patrick, Sheila

“…Although two phenotypes of the opportunistic pathogen Propionibacterium acnes (types I and II) have been described, epidemiological investigations of their…”
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Forty Years of Molecular Diagnostics for Infectious Diseases by Schmitz, Jonathan E, Stratton, Charles W, Persing, David H, Tang, Yi-Wei

“…Nearly 40 years have elapsed since the invention of the PCR, with its extremely sensitive and specific ability to detect nucleic acids via enzyme-mediated…”
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