Search Results - "Persaud, Deborah"
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Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant
Published in The New England journal of medicine (07-11-2013)“…An infant born to a mother with HIV-1 infection was found to have HIV-1 RNA in the blood shortly after birth. Antiretroviral therapy was given but stopped 18…”
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Insights from Clonal Expansion and HIV Persistence in Perinatal Infections
Published in mBio (31-08-2021)“…The latent HIV reservoir forms early in the course of infection and is maintained for life despite effective antiretroviral treatment (ART), including early…”
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3
International AIDS Society global scientific strategy: towards an HIV cure 2016
Published in Nature Medicine (01-08-2016)“…The International AIDS Society Towards a Cure Working Group lays out its scientific strategy to achieve a cure for HIV. Antiretroviral therapy is not curative…”
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Advances in Pediatric HIV-1 Cure Therapies and Reservoir Assays
Published in Viruses (23-11-2022)“…Significant advances in the field of HIV-1 therapeutics to achieve antiretroviral treatment (ART)-free remission and cure for persons living with HIV-1 are…”
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Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa
Published in The Lancet infectious diseases (01-08-2008)“…Summary Assessment of antiretroviral treatment programmes for HIV-infected children in sub-Saharan Africa is important to enable the development of effective…”
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6
HIV Type 1 (HIV-1) Proviral Reservoirs Decay Continuously Under Sustained Virologic Control in HIV-1-Infected Children Who Received Early Treatment
Published in The Journal of infectious diseases (15-11-2014)“…Early initiation of combination antiretroviral therapy (cART) to human immunodeficiency virus type 1 (HIV-1)-infected infants controls HIV-1 replication and…”
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7
Cell-Associated HIV-1 DNA and RNA Decay Dynamics During Early Combination Antiretroviral Therapy in HIV-1-Infected Infants
Published in Clinical infectious diseases (15-12-2015)“…Background. The decay of human immunodeficiency virus type 1 (HIV-1)-infected cells during early combination antiretroviral therapy (cART) in infected infants…”
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8
Immune activation and exhaustion marker expression on T-cell subsets in ART-treated adolescents and young adults with perinatal HIV-1 infection as correlates of viral persistence
Published in Frontiers in immunology (23-03-2023)“…HIV-1 infection in memory CD4+ T cells forms a latent reservoir that is a barrier to cure. Identification of immune biomarkers that correlate with HIV-1…”
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Novel Criteria for Diagnosing Acute and Early Human Immunodeficiency Virus Infection in a Multinational Study of Early Antiretroviral Therapy Initiation
Published in Clinical infectious diseases (02-08-2021)“…Antiretroviral therapy (ART) initiation during acute and early human immunodeficiency virus infection (AEHI) limits HIV reservoir formation and may facilitate…”
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10
Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection
Published in PloS one (08-02-2017)“…The latent reservoir is a major barrier to HIV eradication. Reservoir size is emerging as an important biomarker to assess the likelihood of HIV remission in…”
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Low unspliced cell-associated HIV RNA in early treated adolescents living with HIV on long suppressive ART
Published in Frontiers in immunology (20-02-2024)“…Initiation of antiretroviral treatment (ART) in patients early after HIV-infection and long-term suppression leads to low or undetectable levels of HIV RNA and…”
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12
Raltegravir Pharmacokinetics in Neonates Following Maternal Dosing
Published in Journal of acquired immune deficiency syndromes (1999) (01-11-2014)“…International Maternal Pediatric Adolescent AIDS Clinical Trials P1097 was a multicenter trial to determine washout pharmacokinetics and safety of in…”
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13
Switching children previously exposed to nevirapine to nevirapine-based treatment after initial suppression with a protease-inhibitor-based regimen: long-term follow-up of a randomised, open-label trial
Published in The Lancet infectious diseases (01-07-2012)“…Summary Background Protease-inhibitor-based treatment is recommended as first-line for infants infected with HIV who have been previously exposed to nevirapine…”
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14
Research into a functional cure for HIV in neonates: the need for ethical foresight
Published in The Lancet infectious diseases (01-09-2014)“…Summary In 2013, researchers announced that a newborn child from Mississippi, USA might have been functionally cured of HIV by being given combination…”
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How CD4 + T Cells Transcriptional Profile Is Affected by Culture Conditions: Towards the Design of Optimal In Vitro HIV Reactivation Assays
Published in Biomedicines (01-03-2023)“…Most of the current assays directed at the investigation of HIV reactivation are based on cultures of infected cells such as Peripheral Blood Mononuclear Cells…”
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16
Assessing the Variability of Cell-Associated HIV DNA Quantification through a Multicenter Collaborative Study
Published in Microbiology spectrum (29-06-2022)“…Reliable and accurate quantification of cell-associated HIV DNA (CA HIV DNA) is critical for early infant diagnosis, clinical management of patients under…”
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Novel Single-Cell-Level Phenotypic Assay for Residual Drug Susceptibility and Reduced Replication Capacity of Drug-Resistant Human Immunodeficiency Virus Type 1
Published in Journal of Virology (01-02-2004)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Nevirapine resistance and breast-milk HIV transmission: effects of single and extended-dose nevirapine prophylaxis in subtype C HIV-infected infants
Published in PloS one (2009)“…Daily nevirapine (NVP) prophylaxis to HIV-exposed infants significantly reduces breast-milk HIV transmission. We assessed NVP-resistance in Indian infants…”
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B and T Cell Phenotypic Profiles of African HIV-Infected and HIV-Exposed Uninfected Infants: Associations with Antibody Responses to the Pentavalent Rotavirus Vaccine
Published in Frontiers in immunology (19-01-2018)“…We examined associations between B and T cell phenotypic profiles and antibody responses to the pentavalent rotavirus vaccine (RV5) in perinatally HIV-infected…”
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Identification of Ongoing Human Immunodeficiency Virus Type 1 (HIV-1) Replication in Residual Viremia during Recombinant HIV-1 Poxvirus Immunizations in Patients with Clinically Undetectable Viral Loads on Durable Suppressive Highly Active Antiretroviral Therapy
Published in Journal of Virology (01-10-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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