Search Results - "Perry Gardner, Heather"

BAP1 : a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression by JENSEN, D. E, PROCTOR, M, MINNA, J, BORODOVSKY, A, SCHULTZ, D. C, WILKINSON, K. D, MAUL, G. G, BARLEV, N, BERGER, S. L, PRENDERGAST, G. C, RAUSCHER, F. J, MARQUIS, S. T, GARDNER, H. P, HA, S. I, CHODOSH, L. A, ISHOV, A. M, TOMMERUP, N, VISSING, H, SEKIDO, Y

“…We have identified a novel protein, BAP1, which binds to the RING finger domain of the Breast/Ovarian Cancer Susceptibility Gene product, BRCA1. BAP1 is a…”
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Cloning and Characterization of Krct, a Member of a Novel Subfamily of Serine/Threonine Kinases by Stairs, Douglas B., Perry Gardner, Heather, Ha, Seung I., Copeland, Neal G., Gilbert, Debra J., Jenkins, Nancy A., Chodosh, Lewis A.

“…Protein kinases frequently play key roles in the normal regulation of growth and development in eukaryotic organisms. As a consequence, aberrant expression or…”
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Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues by Rajan, J V, Marquis, S T, Gardner, H P, Chodosh, L A

“…Germline mutations in the putative tumor suppressor gene, BRCA1, predispose women to dramatically elevated risks of breast cancer, while germline mutations in…”
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Protein Kinase Expression during Murine Mammary Development by Chodosh, Lewis A., Gardner, Heather Perry, Rajan, Jayant V., Stairs, Douglas B., Marquis, Sandra T., Leder, Philip A.

“…The susceptibility of the mammary gland to carcinogenesis is influenced by its normal development, particularly during developmental stages such as puberty and…”
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Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland by Gardner, H P, Belka, G K, Wertheim, G B, Hartman, J L, Ha, S I, Gimotty, P A, Marquis, S T, Chodosh, L A

“…The steroid hormones 17 beta-estradiol and progesterone play a central role in the pathogenesis of breast cancer and regulate key phases of mammary gland…”
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Cloning, characterization, and chromosomal localization of Pnck, a Ca(2+)/calmodulin-dependent protein kinase by Gardner, H P, Rajan, J V, Ha, S I, Copeland, N G, Gilbert, D J, Jenkins, N A, Marquis, S T, Chodosh, L A

“…Calcium is an important second messenger in eukaryotic cells. Many of the effects of calcium are mediated via its interaction with calmodulin and the…”
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The caM kinase, Pnck, is spatially and temporally regulated during murine mammary gland development and may identify an epithelial cell subtype involved in breast cancer by Gardner, H P, Ha, S I, Reynolds, C, Chodosh, L A

“…While screening for protein kinases expressed in the murine mammary gland, we identified previously a Ca2+/calmodulin-dependent kinase, Pnck, that is most…”
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The CaM kinase, Pnck, is spatially and temporally regulated during murine mammary gland development and may identify an epithelial cell subtype involved in breast cancers by GARDNER, Heather Perry, HA, Seung I, REYNOLDS, Carol, CHODOSH, Lewis A

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Mammary gland development, reproductive history, and breast cancer risk by Chodosh, L A, D'Cruz, C M, Gardner, H P, Ha, S I, Marquis, S T, Rajan, J V, Stairs, D B, Wang, J Y, Wang, M

“…The observation that normal pathways of differentiation and development are invariably altered during the process of carcinogenesis implies an intrinsic…”
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Cloning, Characterization, and Chromosomal Localization of Pnck, a Ca2+/Calmodulin-Dependent Protein Kinase by Perry Gardner, Heather, Rajan, Jayant V., Ha, Seung I., Copeland, Neal G., Gilbert, Debra J., Jenkins, Nancy A., Marquis, Sandra T., Chodosh, Lewis A.

“…Calcium is an important second messenger in eukaryotic cells. Many of the effects of calcium are mediated via its interaction with calmodulin and the…”
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Cloning and Characterization of Hunk, a Novel Mammalian SNF1-Related Protein Kinase by Gardner, Heather Perry, Wertheim, Gerald B.W., Ha, Seung I., Copeland, Neal G., Gilbert, Debra J., Jenkins, Nancy A., Marquis, Sandra T., Chodosh, Lewis A.

“…We previously identified a novel protein kinase, Hunk, by means of a degenerate PCR screen designed to isolate kinases expressed in the murine mammary gland…”
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Developmental Expression ofBrca2Colocalizes withBrca1and Is Associated with Proliferation and Differentiation in Multiple Tissues by Rajan, Jayant V., Marquis, Sandra T., Gardner, Heather Perry, Chodosh, Lewis A.

“…Germline mutations in the putative tumor suppressor gene,BRCA1,predispose women to dramatically elevated risks of breast cancer, while germline mutations in…”
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Cloning of two novel protein kinases, Hunk and Pnck, and their characterization in mammary development and carcinogenesis by Gardner, Heather Perry

“…Studies of differentiation, development, and carcinogenesis in a variety of biological systems have emphasized the importance of protein kinases in these…”
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