Search Results - "Perry, Crystal L."

Von Willebrand Factor (VWF) multiplex activity assay differentiation of type 1 von Willebrand Disease (VWD) and variant VWD by Roberts, Jonathan C., Christopherson, Pamela A., Tarantino, Michael D., Gonzales, Sarah E., Morateck, Patti A., Perry, Crystal L., Flood, Veronica H., Abshire, Thomas C., Montgomery, Robert R.

“…Introduction VWD diagnosis is challenging requiring multiple VWF activity tests using many individual assays. We have developed an ELISA‐based VWF Multiplex…”
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Prevalence and characterization of anti-VWF antibodies in a population of patients with type 3 VWD by Perry, Crystal L., Christopherson, Pamela A., Agostini, Tina A., Haberichter, Sandra L., Montgomery, Robert R., Flood, Veronica H.

“…•Multiassay strategy was developed to screen, quantify, and characterize neutralizing and nonneutralizing VWF antibodies in VWD plasma.•The prevalence of IgG…”
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Characterization of copy-number variants in a large cohort of patients with von Willebrand disease reveals a relationship between disrupted regions and disease type by Sadler, Brooke, Christopherson, Pamela A., Perry, Crystal L., Bellissimo, Daniel B., Haberichter, Sandra L., Haller, Gabe, Antunes, Lilian, Flood, Veronica H., Di Paola, Jorge, Montgomery, Robert R.

“…Genetic analysis for von Willebrand disease (VWD) commonly utilizes DNA sequencing to identify variants in the von Willebrand factor (VWF) gene; however, this…”
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A novel mouse model of type 2N VWD was developed by CRISPR/Cas9 gene editing and recapitulates human type 2N VWD by Shi, Qizhen, Fahs, Scot A., Mattson, Jeremy G., Yu, Hongyin, Perry, Crystal L., Morateck, Patricia A., Schroeder, Jocelyn A., Rapten, Jessica, Weiler, Hartmut, Montgomery, Robert R.

“…Type 2N von Willebrand disease is caused by mutations in the factor VIII (FVIII) binding site of von Willebrand factor (VWF), resulting in dysfunctional VWF…”
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Characterization of CNVs in a Large Cohort of VWD Patients Reveals Relationship between Disrupted Regions, Clinical Variables and Disease Type by Sadler, Brooke, Christopherson, Pamela A, Perry, Crystal L, Bellissimo, Daniel B., Haberichter, Sandra L, Haller, Gabe, Antunes, Lilian, Flood, Veronica H, Di Paola, Jorge, Montgomery, Robert R, Investigators, The Zimmerman Program

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Molecular pathogenesis and heterogeneity in type 3 VWD families in U.S. Zimmerman program by Christopherson, Pamela A., Haberichter, Sandra L., Flood, Veronica H., Perry, Crystal L., Sadler, Brooke E., Bellissimo, Daniel B., Di Paola, Jorge, Montgomery, Robert R., Abshire, T, Weiler, H, Lillicrap, D, James, P, O’Donnell, J, Ng, C, Bennett, C, Sidonio, R, Manco‐Johnson, M, Journeycake, J, Zia, A, Lusher, J, Rajpurkar, M, Shapiro, A, Lentz, S, Gill, J, Leissinger, C, Ragni, M, Tarantino, M, Roberts, J, Hord, J, Strouse, J, Ma, A, Valentino, L, Boggio, L, Sharathkumar, A, Gruppo, R, Kerlin, B, Kulkarni, R, Green, D, Hoots, K, Brown, D, Mahoney, D, Mathias, L, Bedros, A, Diamond, C, Neff, A, DiMichele, D, Giardina, P, Cohen, A, Paidas, M, Werner, E, Matsunaga, A, Shafer, F, Konkle, B, Cuker, A, Kouides, P, Stein, D

“…Background Type 3 von Willebrand Disease (VWD) is a rare and severe form of VWD characterized by the absence of von Willebrand factor (VWF). Objectives As part…”
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Genotype-Phenotype Relationship and the Role of Alloantibodies in Type 3 VWD in the Zimmerman Program by Christopherson, Pamela A, Perry, Crystal L, Bellissimo, Daniel B., Flood, Veronica H, Gill, Joan Cox, Haberichter, Sandra L, Montgomery, Robert R., Investigators, Zimmerman Program

“…Type 3 von Willebrand Disease (VWD) is the rarest and most severe form of VWD and is characterized by the complete absence of von Willebrand factor (VWF)…”
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Characterization and Expression of an In-Frame Exon 33-34 Deletion Causing Type 1 VWD by Cartwright, Ashley, Christopherson, Pamela A, Perry, Crystal L., Haberichter, Sandra L, Hampshire, Daniel, Peake, Ian R., Goodeve, Anne, Montgomery, Robert R, Bellissimo, Daniel B.

“…Introduction: In recent years, the role of copy number variation (CNV) in the pathogenesis of type 1 von Willebrand disease (VWD) has been extensively…”
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Factor VIII Inhibitors: Von Willebrand Factor Makes A Difference In Vitroand In Vivo by Shi, Qizhen, Kuether, Erin L., Schroeder, Jocelyn A., Perry, Crystal L., Fahs, Scot A., Montgomery, Robert R.

“…Abstract 709 The important association between von Willebrand factor (VWF) and factor VIII (FVIII) has been investigated for decades, but the effect of VWF on…”
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Factor VIII Inhibitors: Von Willebrand Factor Makes A Difference In Vitro and In Vivo by Shi, Qizhen, Kuether, Erin L., Schroeder, Jocelyn A., Perry, Crystal L., Fahs, Scot A., Montgomery, Robert R.

“…Abstract Abstract 709 The important association between von Willebrand factor (VWF) and factor VIII (FVIII) has been investigated for decades, but the effect…”
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