Search Results - "Perrot–Applanat, Martine"
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High AHR expression in breast tumors correlates with expression of genes from several signaling pathways namely inflammation and endogenous tryptophan metabolism
Published in PloS one (10-01-2018)“…Increasing epidemiological and animal experimental data provide substantial support for the role of aryl hydrocarbon receptor (AhR) in mammary tumorigenesis…”
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Differential gene expression in growth factors, epithelial mesenchymal transition and chemotaxis in the diffuse type compared with the intestinal type of gastric cancer
Published in Oncology letters (01-07-2019)“…Gastric cancer (GC) is a highly heterogeneous disease and one of the major causes of cancer-related mortality worldwide. Diffuse-type gastric adenocarcinoma…”
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High Expression of AhR and Environmental Pollution as AhR-Linked Ligands Impact on Oncogenic Signaling Pathways in Western Patients with Gastric Cancer-A Pilot Study
Published in Biomedicines (01-08-2024)“…The vast majority of gastric cancer (GC) cases are adenocarcinomas including intestinal and diffuse GC. The incidence of diffuse GC, often associated with poor…”
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Xenoestrogens modulate vascular endothelial growth factor secretion in breast cancer cells through an estrogen receptor-dependent mechanism
Published in Journal of endocrinology (01-02-2008)“…Environmental chemicals may affect human health by disrupting endocrine function. Their possible role in the mammary gland and breast tumors is still unknown…”
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Differential Expression of Genes Involved in Metabolism and Immune Response in Diffuse and Intestinal Gastric Cancers, a Pilot Ptudy
Published in Biomedicines (23-01-2022)“…Gastric cancer (GC) is one of the major causes of cancer-related mortality worldwide. The vast majority of GC cases are adenocarcinomas including intestinal…”
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Similar NF-κB gene signatures in TNF-α treated human endothelial cells and breast tumor biopsies
Published in PloS one (2011)“…Endothelial dysfunction has been implicated in the pathogenesis of diverse pathologies ranging from vascular and immune diseases to cancer. TNF-α is one of the…”
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A Dynamic Shift of VEGF Isoforms with a Transient and Selective Progesterone-Induced Expression of VEGF189 Regulates Angiogenesis and Vascular Permeability in Human Uterus
Published in Proceedings of the National Academy of Sciences - PNAS (30-04-2002)“…A key mechanism underlying physiological angiogenesis of the human endometrium is its ability to regenerate the vascular capillary network and to perform…”
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Vascular endothelial growth factor VEGF189 induces human neutrophil chemotaxis in extravascular tissue via an autocrine amplification mechanism
Published in Laboratory investigation (01-04-2004)“…Vascular endothelial growth factor (VEGF) is a potent and specific endothelial cell mitogen involved in normal and pathological angiogenesis. Our group…”
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Overexpression of VEGF189 in breast cancer cells induces apoptosis via NRP1 under stress conditions
Published in Cell adhesion & migration (01-07-2011)“…The existence of multiple VEGF-A isoforms raised the possibility that they may have distinct functions in tumor growth. We have previously published that…”
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VEGF189 stimulates endothelial cells proliferation and migration in vitro and up-regulates the expression of Flk-1/KDR mRNA
Published in Experimental cell research (10-09-2005)“…The vascular endothelial growth factor (VEGF) is a critical factor for development of the vascular system in physiological and pathological angiogenesis. This…”
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Autocrine functions of VEGF in breast tumor cells: Adhesion, survival, migration and invasion
Published in Cell adhesion & migration (01-11-2012)“…Vascular endothelial growth factor A (VEGF-A) is well known for its key roles in blood vessel growth. Although most studies on VEGF and VEGF receptors have…”
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Alteration of mammary gland development by bisphenol a and evidence of a mode of action mediated through endocrine disruption
Published in Molecular and cellular endocrinology (05-11-2018)“…The development and function of the mammary gland are endocrine-dependent processes, depending on the stage of development. Foetal and/or postnatal exposure to…”
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Paracrine action of vascular endothelial growth factor in the human endometrium: production and target sites, and hormonal regulation
Published in Angiogenesis (London) (1998)“…Vascular endothelial growth factor (VEGF) is an endothelium-specific growth factor with potent angiogenic activity and a stimulator of microvascular…”
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Ovarian steroids in endometrial angiogenesis
Published in Steroids (01-10-2000)“…Angiogenesis, the sprouting of new blood vessels from pre-existing ones, is fundamental for human endometrial development and differentiation, which are…”
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Journal Article Conference Proceeding -
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Mechanisms of nuclear localization of the progesterone receptor: evidence for interaction between monomers
Published in Cell (30-06-1989)“…Deletion mutants of the rabbit progesterone receptor were used to identify two major mechanisms of its nuclear localization. A putative signal sequence,…”
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Detection of Persistent Organic Pollutants in Omental Adipose Tissue from Patients with Diffuse-Gastric Cancer: A Pilot Study
Published in Cancers (01-10-2021)“…The greater omentum represents a specific adipose tissue resected with gastric surgery for cancer. Diffuse gastric adenocarcinoma (diffuse-GC) is of major…”
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MDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics
Published in British journal of cancer (01-09-2015)“…Background: Vascular endothelial growth factor (VEGF) is a multifunctional cytokine that has important roles in angiogenesis. Our knowledge of the significance…”
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Vascular endothelial growth factor is a target gene for estrogen receptor and contributes to breast cancer progression
Published in Advances in experimental medicine and biology (2008)“…Tumor growth requires the development and remodeling of the vascular system, involving paracrine signaling between various growth factors and endothelial…”
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