Search Results - "Perrot, Y."

Prostaglandin E2 breaks down pericyte–endothelial cell interaction via EP1 and EP4-dependent downregulation of pericyte N-cadherin, connexin-43, and R-Ras by Perrot, Carole Y., Herrera, Jose L., Fournier-Goss, Ashley E., Komatsu, Masanobu

“…A close association between pericytes and endothelial cells (ECs) is crucial to the stability and function of capillary blood vessels and microvessels. The…”
Get full text

GATE V6: a major enhancement of the GATE simulation platform enabling modelling of CT and radiotherapy by Jan, S, Benoit, D, Becheva, E, Carlier, T, Cassol, F, Descourt, P, Frisson, T, Grevillot, L, Guigues, L, Maigne, L, Morel, C, Perrot, Y, Rehfeld, N, Sarrut, D, Schaart, D R, Stute, S, Pietrzyk, U, Visvikis, D, Zahra, N, Buvat, I

“…GATE (Geant4 Application for Emission Tomography) is a Monte Carlo simulation platform developed by the OpenGATE collaboration since 2001 and first publicly…”
Get more information

Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit by Bernal, M.A, Bordage, M.C, Brown, J.M.C, Davídková, M, Delage, E, El Bitar, Z, Enger, S.A, Francis, Z, Guatelli, S, Ivanchenko, V.N, Karamitros, M, Kyriakou, I, Maigne, L, Meylan, S, Murakami, K, Okada, S, Payno, H, Perrot, Y, Petrovic, I, Pham, Q.T, Ristic-Fira, A, Sasaki, T, Štěpán, V, Tran, H.N, Villagrasa, C, Incerti, S

“…Highlights • A review of the current status of Geant4-DNA is presented. • New physical models describing the interactions of electrons in water are described…”
Get full text

MINAS TIRITH: a new tool for simulating radiation-induced DNA damage at the cell population level by Thibaut, Y, Gonon, G, Martinez, J S, Petit, M, Vaurijoux, A, Gruel, G, Villagrasa, C, Incerti, S, Perrot, Y

“… The mechanisms of radiation-induced DNA damage can be understood via the fundamental acquisition of knowledge through a combination of experiments and…”
Get more information

Secondary neutron dose contribution from pencil beam scanning, scattered and spatially fractionated proton therapy by Leite, A M M, Ronga, M G, Giorgi, M, Ristic, Y, Perrot, Y, Trompier, F, Prezado, Y, Créhange, G, De Marzi, L

“…The Orsay Proton therapy Center (ICPO) has a long history of intracranial radiotherapy using both double scattering (DS) and pencil beam scanning (PBS)…”
Get more information

DNA damage modeled with Geant4-DNA: effects of plasmid DNA conformation and experimental conditions by D-Kondo, N, Moreno-Barbosa, E, Štěphán, V, Stefanová, K, Perrot, Y, Villagrasa, C, Incerti, S, De Celis Alonso, B, Schuemann, J, Faddegon, B, Ramos-Méndez, J

“…The chemical stage of the Monte Carlo track-structure (MCTS) code Geant4-DNA was extended for its use in DNA strand break (SB) simulations and compared against…”
Get more information

Numerical study of shock/boundary layer interaction in supersonic overexpanded nozzles by Hadjadj, A., Perrot, Y., Verma, S.

“…A numerical study, using a mixed finite element/finite volume method on unstructured meshes adapted for compressible flows, is conducted to investigate…”
Get full text

PDB4DNA: Implementation of DNA geometry from the Protein Data Bank (PDB) description for Geant4-DNA Monte-Carlo simulations by Delage, E., Pham, Q.T., Karamitros, M., Payno, H., Stepan, V., Incerti, S., Maigne, L., Perrot, Y.

“…This paper describes PDB4DNA, a new Geant4 user application, based on an independent, cross-platform, free and open source C++ library, so-called PDBlib, which…”
Get full text

Valproic acid inhibits proliferation and induces apoptosis in acute myeloid leukemia cells expressing P-gp and MRP1 by TANG, R, FAUSSAT, A.-M, MAJDAK, P, PERROT, J.-Y, CHAOUI, D, LEGRAND, O, MARIE, J.-P

“…The multidrug resistance (MDR) phenotype, induced by the overexpression of several ABC transporters or by antiapoptotic mechanisms, has been identified as the…”
Get full text

Comparison of GATE/GEANT4 with EGSnrc and MCNP for electron dose calculations at energies between 15 keV and 20 MeV by Maigne, L, Perrot, Y, Schaart, D R, Donnarieix, D, Breton, V

“…The GATE Monte Carlo simulation platform based on the GEANT4 toolkit has come into widespread use for simulating positron emission tomography (PET) and single…”
Get more information

Complex data labeling with deep learning methods: Lessons from fisheries acoustics by Sarr, Jean-Michel A., Brochier, Timothée, Brehmer, P., Perrot, Y., Bah, A., Sarré, A., Jeyid, M.A., Sidibeh, M., El Ayoubi, S.

“…Quantitative and qualitative analysis of acoustic backscattered signals from the seabed bottom to the sea surface is used worldwide for fish stocks assessment…”
Get full text

Dose point kernels in liquid water: An intra-comparison between GEANT4-DNA and a variety of Monte Carlo codes by Champion, C., Incerti, S., Perrot, Y., Delorme, R., Bordage, M.C., Bardiès, M., Mascialino, B., Tran, H.N., Ivanchenko, V., Bernal, M., Francis, Z., Groetz, J.-E., Fromm, M., Campos, L.

“…Modeling the radio-induced effects in biological medium still requires accurate physics models to describe the interactions induced by all the charged…”
Get full text

Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study by Incerti, S., Psaltaki, M., Gillet, P., Barberet, Ph, Bardiès, M., Bernal, M.A., Bordage, M.-C., Breton, V., Davidkova, M., Delage, E., El Bitar, Z., Francis, Z., Guatelli, S., Ivanchenko, A., Ivanchenko, V., Karamitros, M., Lee, S.B., Maigne, L., Meylan, S., Murakami, K., Nieminen, P., Payno, H., Perrot, Y., Petrovic, I., Pham, Q.T., Ristic-Fira, A., Santin, G., Sasaki, T., Seznec, H., Shin, J.I., Stepan, V., Tran, H.N., Villagrasa, C.

“…An accurate modeling of radial energy deposition around ion tracks is a key requirement of radiation transport software used for simulations in radiobiology at…”
Get full text

Internal dosimetry through GATE simulations of preclinical radiotherapy using a melanin-targeting ligand by Perrot, Y, Degoul, F, Auzeloux, P, Bonnet, M, Cachin, F, Chezal, J M, Donnarieix, D, Labarre, P, Moins, N, Papon, J, Rbah-Vidal, L, Vidal, A, Miot-Noirault, E, Maigne, L

“…The GATE Monte Carlo simulation platform based on the Geant4 toolkit is under constant improvement for dosimetric calculations. In this study, we explore its…”
Get more information

Monocytes and macrophages: emerging mechanisms and novel therapeutic targets in pulmonary fibrosis by Perrot, Carole Y, Karampitsakos, Theodoros, Herazo-Maya, Jose D

“…Pulmonary fibrosis results from a plethora of abnormal pathogenetic events. In idiopathic pulmonary fibrosis (IPF), inhalational, environmental, or…”
Get more information

ABLE, an innovative transparent exoskeleton for the upper-limb by Garrec, P., Friconneau, J.P., Measson, Y., Perrot, Y.

“…This paper presents ABLE, an innovative exoskeleton for the upper limb currently under development at CEA-LIST Interactive Robotics Unit. Its distinctive high…”
Get full text

Prolonged activation of cAMP signaling leads to endothelial barrier disruption via transcriptional repression of RRAS by Perrot, Carole Y., Sawada, Junko, Komatsu, Masanobu

“…ABSTRACT The increase in cAMP levels in endothelial cells triggers cellular signaling to alter vascular permeability. It is generally considered that cAMP…”
Get full text

Comparison of Geant4-DNA simulation of S-values with other Monte Carlo codes by André, T., Morini, F., Karamitros, M., Delorme, R., Le Loirec, C., Campos, L., Champion, C., Groetz, J.-E., Fromm, M., Bordage, M.-C., Perrot, Y., Barberet, Ph, Bernal, M.A., Brown, J.M.C., Deleuze, M.S., Francis, Z., Ivanchenko, V., Mascialino, B., Zacharatou, C., Bardiès, M., Incerti, S.

“…Monte Carlo simulations of S-values have been carried out with the Geant4-DNA extension of the Geant4 toolkit. The S-values have been simulated for…”
Get full text

Coupling of Geant4-DNA physics models into the GATE Monte Carlo platform: Evaluation of radiation-induced damage for clinical and preclinical radiation therapy beams by Pham, Q.T., Anne, A., Bony, M., Delage, E., Donnarieix, D., Dufaure, A., Gautier, M., Lee, S.B., Micheau, P., Montarou, G., Perrot, Y., Shin, J.I., Incerti, S., Maigne, L.

“…The GATE Monte Carlo simulation platform based on the Geant4 toolkit is in constant improvement for dosimetric calculations. In this paper, we present the…”
Get full text

SU‐E‐T‐708: Validation of the New GATE 6.0 Monte Carlo Platform for Radiation Therapy. Investigations on Simulation Parameters by Perrot, Y, Donnarieix, D, Breton, V, Maigne, L

“…Purpose: In this study, we validate the accuracy of the new GATE 6.0 Monte Carlo platform (using GEANT4 9.2 Standard Electromagnetic Physics Package) to model…”
Get full text