Search Results - "Perron, Karl"

The transcriptional regulator CzcR modulates antibiotic resistance and quorum sensing in Pseudomonas aeruginosa by Dieppois, Guennaëlle, Ducret, Véréna, Caille, Olivier, Perron, Karl

“…The opportunistic pathogen Pseudomonas aeruginosa responds to zinc, cadmium and cobalt by way of the CzcRS two-component system. In presence of these metals…”
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The CzcCBA Efflux System Requires the CadA P-Type ATPase for Timely Expression Upon Zinc Excess in Pseudomonas aeruginosa by Ducret, Verena, Gonzalez, Manuel R., Leoni, Sara, Valentini, Martina, Perron, Karl

“…Zinc (Zn) is a trace element essential for life but can be toxic if present in excess. While cells have import systems to guarantee a vital Zn intracellular…”
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A Zur-mediated transcriptional regulation of the zinc export system in Pseudomonas aeruginosa by Ducret, Verena, Gonzalez, Diego, Leoni, Sara, Valentini, Martina, Perron, Karl

“…The control of cellular zinc (Zn) concentrations by dedicated import and export systems is essential for the survival and virulence of Pseudomonas aeruginosa…”
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A Copper-Activated Two-Component System Interacts with Zinc and Imipenem Resistance in Pseudomonas aeruginosa by CAILLE, Olivier, ROSSIER, Claude, PERRON, Karl

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Preventing Antibiotic-Resistant Infections: Additively Manufactured Porous Ti6Al4V Biofunctionalized with Ag and Fe Nanoparticles by Putra, Niko E., Leeflang, Marius A., Ducret, Verena, Patrulea, Viorica, Fratila-Apachitei, Lidy E., Perron, Karl, Ye, Hua, Zhou, Jie, Apachitei, Iulian, Zadpoor, Amir A.

“…Implant-associated infections are highly challenging to treat, particularly with the emergence of multidrug-resistant microbials. Effective preventive action…”
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Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages by Abdel-Sayed, Philippe, Kaeppeli, Ariane, Siriwardena, Thissa, Darbre, Tamis, Perron, Karl, Jafari, Paris, Reymond, Jean-Louis, Pioletti, Dominique P., Applegate, Lee Ann

“…Multi-drug resistant Pseudomonas aeruginosa has increased progressively and impedes further regression in mortality in burn patients. Such wound infections…”
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type III-like restriction endonuclease functions as a major barrier to horizontal gene transfer in clinical Staphylococcus aureus strains by Corvaglia, Anna R, François, Patrice, Hernandez, David, Perron, Karl, Linder, Patrick, Schrenzel, Jacques

“…Staphylococcus aureus is an versatile pathogen that can cause life-threatening infections. Depending on the clinical setting, up to 50% of S. aureus infections…”
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One-step Bio-guided Isolation of Secondary Metabolites from the Endophytic Fungus Penicillium crustosum Using High-resolution Semi-preparative HPLC by Alfattani, Abdulelah, Queiroz, Emerson Ferreira, Marcourt, Laurence, Leoni, Sara, Stien, Didier, Hofstetter, Valerie, Gindro, Katia, Perron, Karl, Wolfender, Jean-Luc

“…An endophytic fungal strain was isolated from the seagrass and investigated to identify its antimicrobial constituents and characterize its metabolome…”
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Global Analysis of the Zinc Homeostasis Network in Pseudomonas aeruginosa and Its Gene Expression Dynamics by Ducret, Verena, Abdou, Melina, Goncalves Milho, Catarina, Leoni, Sara, Martin--Pelaud, Oriane, Sandoz, Antoine, Segovia Campos, Inés, Tercier-Waeber, Mary-Lou, Valentini, Martina, Perron, Karl

“…Zinc is one of the most important trace elements for life and its deficiency, like its excess, can be fatal. In the bacterial opportunistic pathogen…”
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In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA by Slepikas, Liudas, Chiriano, Gianpaolo, Perozzo, Remo, Tardy, Sébastien, Kranjc, Agata, Patthey-Vuadens, Ophélie, Ouertatani-Sakouhi, Hajer, Kicka, Sébastien, Harrison, Christopher F, Scrignari, Tiziana, Perron, Karl, Hilbi, Hubert, Soldati, Thierry, Cosson, Pierre, Tarasevicius, Eduardas, Scapozza, Leonardo

“…Here, we report on the design, synthesis, and biological evaluation of 4-thiazolidinone (rhodanine) derivatives targeting Mycobacterial tuberculosis (Mtb)…”
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Transcriptome Analysis of Pseudomonas aeruginosa Cultured in Human Burn Wound Exudates by Gonzalez, Manuel R, Ducret, Verena, Leoni, Sara, Fleuchot, Betty, Jafari, Paris, Raffoul, Wassim, Applegate, Lee A, Que, Yok-Ai, Perron, Karl

“…is a severe opportunistic pathogen and is one of the major causes of hard to treat burn wound infections. Herein we have used an RNA-seq transcriptomic…”
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Chemo-Diversification of Plant Extracts Using a Generic Bromination Reaction and Monitoring by Metabolite Profiling by Righi, Davide, Marcourt, Laurence, Koval, Alexey, Ducret, Verena, Pellissier, Léonie, Mainetti, Alice, Katanaev, Vladimir L, Perron, Karl, Wolfender, Jean-Luc, Queiroz, Emerson Ferreira

“…A generic procedure for direct bromination of polyphenol in crude plant extracts was developed to generate multiple “unnatural” halogenated natural products…”
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CzcR-CzcS, a Two-component System Involved in Heavy Metal and Carbapenem Resistance in Pseudomonas aeruginosa by Perron, Karl, Caille, Olivier, Rossier, Claude, van Delden, Christian, Dumas, Jean-Luc, Köhler, Thilo

“…Pseudomonas aeruginosa is an environmental bacterium involved in mineralization of organic matter. It is also an opportunistic pathogen able to cause serious…”
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Investigation of temperature conditions in Swiss urban and suburban microhabitats for the overwintering suitability of diapausing Aedes albopictus eggs by Ravasi, Damiana, Guidi, Valeria, Flacio, Eleonora, Lüthy, Peter, Perron, Karl, Lüdin, Samuel, Tonolla, Mauro

“…In Switzerland, the invasive Asian tiger mosquito, Aedes albopictus, is firmly established in the Canton of Ticino, south of the Alps. According to a…”
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Chiral Separation of Stilbene Dimers Generated by Biotransformation for Absolute Configuration Determination and Antibacterial Evaluation by Huber, Robin, Marcourt, Laurence, Quiros-Guerrero, Luis-Manuel, Luscher, Alexandre, Schnee, Sylvain, Michellod, Emilie, Ducret, Verena, Kohler, Thilo, Perron, Karl, Wolfender, Jean-Luc, Gindro, Katia, Ferreira Queiroz, Emerson

“…A series of complex stilbene dimers have been generated through biotransformation of resveratrol, pterostilbene, and the mixture of both using the enzymatic…”
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Effect of Human Burn Wound Exudate on Pseudomonas aeruginosa Virulence by Gonzalez, Manuel R, Fleuchot, Betty, Lauciello, Leonardo, Jafari, Paris, Applegate, Lee Ann, Raffoul, Wassim, Que, Yok-Ai, Perron, Karl

“…Burn wound sepsis is currently the main cause of morbidity and mortality after burn trauma. Infections by notorious pathogens such as Pseudomonas aeruginosa,…”
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Combination of Pseudo-LC-NMR and HRMS/MS-Based Molecular Networking for the Rapid Identification of Antimicrobial Metabolites From Fusarium petroliphilum by Alfattani, Abdulelah, Marcourt, Laurence, Hofstetter, Valérie, Queiroz, Emerson Ferreira, Leoni, Sara, Allard, Pierre-Marie, Gindro, Katia, Stien, Didier, Perron, Karl, Wolfender, Jean-Luc

“…An endophytic fungal strain isolated from a seagrass endemic to the Mediterranean Sea ( Posidonia oceanica ) was studied in order to identify its antimicrobial…”
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Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of Lasiodiplodia venezuelensis by Pellissier, Léonie, Koval, Alexey, Marcourt, Laurence, Ferreira Queiroz, Emerson, Lecoultre, Nicole, Leoni, Sara, Quiros-Guerrero, Luis-Manuel, Barthélémy, Morgane, Duivelshof, Bastiaan L., Guillarme, Davy, Tardy, Sébastien, Eparvier, Véronique, Perron, Karl, Chave, Jérôme, Stien, Didier, Gindro, Katia, Katanaev, Vladimir, Wolfender, Jean-Luc

“…The Wnt signaling pathway controls multiple events during embryonic development of multicellular animals and is carcinogenic when aberrantly activated in…”
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Characterization of Pseudomonas aeruginosa Quorum Sensing Inhibitors from the Endophyte Lasiodiplodia venezuelensis and Evaluation of Their Antivirulence Effects by Metabolomics by Pellissier, Léonie, Leoni, Sara, Marcourt, Laurence, Ferreira Queiroz, Emerson, Lecoultre, Nicole, Quiros-Guerrero, Luis-Manuel, Barthélémy, Morgane, Eparvier, Véronique, Chave, Jérôme, Stien, Didier, Gindro, Katia, Perron, Karl, Wolfender, Jean-Luc

“…The opportunistic pathogen Pseudomonas aeruginosa is one of the “critical priority pathogens” due to its multidrug resistance to a wide range of antibiotics…”
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Posttranscriptional Control of Quorum-Sensing-Dependent Virulence Genes by DksA in Pseudomonas aeruginosa by Jude, Florence, Kohler, Thilo, Branny, Pavel, Perron, Karl

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