Search Results - "Perrin, J."
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1
The impact of drugs on male fertility: a review
Published in Andrology (Oxford) (01-07-2017)“…Summary Beside cytotoxic drugs, other drugs can impact men's fertility through various mechanisms. Via the modification of the hypothalamic–pituitary–gonadal…”
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2
Challenges and opportunities in the use of ponds and pondscapes as Nature-based Solutions
Published in Hydrobiologia (01-09-2023)“…Ponds and “pondscapes” (networks of ponds) are crucial habitats for biodiversity and for delivering multiple benefits to humans, so-called “Nature’s…”
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3
Stereocilia morphogenesis and maintenance through regulation of actin stability
Published in Seminars in cell & developmental biology (01-05-2017)“…Stereocilia are actin-based protrusions on auditory and vestibular sensory cells that are required for hearing and balance. They convert physical force from…”
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hERG K(+) channels: structure, function, and clinical significance
Published in Physiological reviews (01-07-2012)“…The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the rapid component of the delayed rectifier K(+) channel, Kv11.1, which are…”
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The actin gene family: Function follows isoform
Published in Cytoskeleton (Hoboken, N.J.) (01-10-2010)“…Although actin is often thought of as a single protein, in mammals it actually consists of six different isoforms encoded by separate genes. Each isoform is…”
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Resolution of inflammation by retrograde chemotaxis of neutrophils in transgenic zebrafish
Published in Journal of leukocyte biology (01-12-2006)“…Neutrophil chemotaxis to sites of inflammation is a critical process during normal immune responses to tissue injury and infection and pathological immune…”
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Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders
Published in Nature neuroscience (01-09-2021)“…Understanding the tissue-specific genetic controls of protein levels is essential to uncover mechanisms of post-transcriptional gene regulation. In this study,…”
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Cattle herd typology for epidemiology, surveillance, and animal welfare: Method and applications in France
Published in Preventive veterinary medicine (01-06-2019)“…Depending on the objectives (economic, sociology, epidemiology…), many different methods and data are used to classify cattle herds. The use of different and…”
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EVOLUTION OF THE DUST SIZE DISTRIBUTION OF COMET 67P/CHURYUMOV-GERASIMENKO FROM 2.2 au TO PERIHELION
Published in The Astrophysical journal (10-04-2016)“…ABSTRACT The Rosetta probe, orbiting Jupiter-family comet 67P/Churyumov-Gerasimenko, has been detecting individual dust particles of mass larger than 10−10 kg…”
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Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs
Published in Cell host & microbe (14-10-2015)“…The malaria parasite Plasmodium falciparum replicates within erythrocytes, producing progeny merozoites that are released from infected cells via a poorly…”
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Detecting objective and subjective cognitive effects of electroconvulsive therapy: intensity, duration and test utility in a large clinical sample
Published in Psychological medicine (01-10-2014)“…Electroconvulsive therapy (ECT) is an effective treatment for depression but the extent and persistence of cognitive side-effects remain uncertain. It has been…”
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Water quality assessment of highly polluted rivers in a semi-arid Mediterranean zone Oued Fez and Sebou River (Morocco)
Published in Journal of hydrology (Amsterdam) (14-03-2014)“…•We characterised spatial and temporal variations in concentrations and loads.•The analysis is based on field data (17 campaigns – 8 location network).•We…”
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A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain
Published in Alzheimer's research & therapy (09-08-2019)“…Alzheimer's disease (AD) is the most common form of dementia. This neurodegenerative disorder is associated with neuronal death and gliosis heavily impacting…”
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The Plasmodium falciparum rhoptry bulb protein RAMA plays an essential role in rhoptry neck morphogenesis and host red blood cell invasion
Published in PLoS pathogens (06-09-2019)“…The malaria parasite Plasmodium falciparum invades, replicates within and destroys red blood cells in an asexual blood stage life cycle that is responsible for…”
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Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery
Published in PLoS biology (10-05-2019)“…Cyclic AMP (cAMP) is an important signalling molecule across evolution, but its role in malaria parasites is poorly understood. We have investigated the role…”
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Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci
Published in PLoS genetics (26-10-2021)“…Chromatin accessibility and gene expression in relevant cell contexts can guide identification of regulatory elements and mechanisms at genome-wide association…”
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Sol-gel route: An original strategy to chemically stabilize proton exchange membranes for fuel cell
Published in Journal of power sources (30-06-2020)“…We present the elaboration, via a Sol-Gel (SG) route, of a new generation of hybrid membranes for PEMFC applications, in order to improve their performances…”
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Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins
Published in Nature communications (21-04-2015)“…Auditory sensory hair cells depend on stereocilia with precisely regulated lengths to detect sound. Since stereocilia are primarily composed of crosslinked,…”
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Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community‐engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4
Published in Alzheimer's & dementia (01-01-2023)“…Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to validate biomarkers for Alzheimer's disease (AD) clinical trials. To improve…”
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Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis
Published in Frontiers in psychiatry (28-06-2019)“…Glucocorticoid resistance-reduced function of the glucocorticoid receptor (GR)-is seen in many depressed patients. It is argued that this resistance to…”
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