Search Results - "Perrin, C. L."

Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance by He, Y, Wu, A C, Harrington, B S, Davies, C M, Wallace, S J, Adams, M N, Palmer, J S, Roche, D K, Hollier, B G, Westbrook, T F, Hamidi, H, Konecny, G E, Winterhoff, B, Chetty, N P, Crandon, A J, Oliveira, N B, Shannon, C M, Tinker, A V, Gilks, C B, Coward, J I, Lumley, J W, Perrin, L C, Armes, J E, Hooper, J D

“…Hematogenous metastases are rarely present at diagnosis of ovarian clear cell carcinoma (OCC). Instead dissemination of these tumors is characteristically via…”
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EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface by Adams, M N, Harrington, B S, He, Y, Davies, C M, Wallace, S J, Chetty, N P, Crandon, A J, Oliveira, N B, Shannon, C M, Coward, J I, Lumley, J W, Perrin, L C, Armes, J E, Hooper, J D

“…Many cancers are dependent on inappropriate activation of epidermal growth factor receptor (EGFR), and drugs targeting this receptor can improve patient…”
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Conservative surgery to preserve ovarian function in patients with malignant ovarian germ cell tumors: A review of 74 cases by LOW, J. J. H, PERRIN, L. C, CRANDON, A. J, HACKER, N. F

“…Effective combination chemotherapy has improved the previously dismal prognosis for malignant ovarian germ cell tumors (MOGCT) dramatically. In young patients,…”
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Manual removal of suspected placenta accreta at cesarean hysterectomy by Yap, Y.Y, Perrin, L.C, Pain, S.R, Wong, S.F, Chan, F.Y

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Local Recurrence in High-Risk Node-Negative Stage I Endometrial Carcinoma Treated with Postoperative Vaginal Vault Brachytherapy by Ng, T.Y., Perrin, L.C., Nicklin, J.L., Cheuk, R., Crandon, A.J.

“…Objectives. The aim of this study is to examine the patterns of failure after extended surgical staging and postoperative vaginal vault brachytherapy as the…”
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Symmetries of Hydrogen Bonds in Solution by Perrin, Charles L.

“…The nuclear magnetic resonance method of isotopic perturbation can distinguish between single- and double-well potentials in intramolecularly hydrogen-bonded…”
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Postoperative Vaginal Vault Brachytherapy for Node-Negative Stage II (Occult) Endometrial Carcinoma by Ng, T.Y., Nicklin, J.L., Perrin, L.C., Cheuk, R., Crandon, A.J.

“…Objective. The aim of this study is to look at the efficacy of extended surgical staging and postoperative vaginal vault brachytherapy in patients with Stage…”
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Early-stage vaginal carcinoma--an analysis of 70 patients by Otton, G R, Nicklin, J L, Dickie, G J, Niedetzky, P, Tripcony, L, Perrin, L C, Crandon, A J

“…The aims of this study were to assess outcomes and define prognostic factors for early-stage vaginal carcinoma. A retrospective analysis was performed of women…”
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Anemia before and during concurrent chemoradiotherapy in patients with cervical carcinoma: Effect on progression-free survival by Obermair, A, Cheuk, R, Horwood, K, Neudorfer, M, Janda, M, Giannis, G, Nicklin, J L, Perrin, L C, Crandon, A J

“…To determine the impact of anemia before and during chemoradiation in patients with cervical cancer, we collected data on hemoglobin (Hb) levels before and…”
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Stereoelectronic Control in Addition of Nucleophiles to an Amidinium Ion by Perrin, Charles L, Young, David B

“…Nucleophilic addition to 1,3-dimethyl-5-phenyl-1,4,5,6-tetrahydropyrimidinium ion provides a quantitative measure of stereoelectronic control. This amidinium…”
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Is There Stereoelectronic Control in Hydrolysis of Cyclic Guanidinium Ions? by Perrin, Charles L, Young, David B

“…To assess stereoelectronic effects in the cleavage of tetrahedral intermediates, a series of five-, six-, and seven-membered cyclic guanidinium salts was…”
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"Strong" hydrogen bonds in chemistry and biology by Perrin, C L, Nielson, J B

“…Hydrogen bonds are a key feature of chemical structure and reactivity. Recently there has been much interest in a special class of hydrogen bonds called…”
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Barminomycin forms GC-specific adducts and virtual interstrand crosslinks with DNA by Perrin, Leah C., Cullinane, Carleen, Phillips, Don R., Kimura, Ken-ichi

“…The sequence specificity of the binding of barminomycin (SN-07 chromophore) to DNA was investigated using an in vitro transcription assay. It was found that…”
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Reverse anomeric effect and steric hindrance to solvation of ionic groups by Perrin, C. L.

“…Abstract…”
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Microinvasive Adenocarcinoma of the Cervix by Nicklin, J.L., Perrin, L.C., Crandon, A.J., Ward, B.G.

“…We evaluated the management of patients with microinvasive adenocarcinoma of the cervix (MIAC), in particular, to determine the place of conservative surgery,…”
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Safety and Efficacy of Low Anterior en Bloc Resection as Part of Cytoreductive Surgery for Patients with Ovarian Cancer by Obermair, Andreas, Hagenauer, Sabine, Tamandl, Dietmar, Clayton, Rick D., Nicklin, James L., Perrin, Lewis C., Ward, Bruce G., Crandon, Alex J.

“…Objective. To examine the feasibility and safety of a low anterior resection of the rectosigmoid plus adjacent pelvic tumour as part of primary cytoreduction…”
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Impact of hemoglobin levels before and during concurrent chemoradiotherapy on the response of treatment in patients with cervical carcinoma: Preliminary results by OBERMAIR, Andreas, CHEUK, Robyn, HORWOOD, Keith, JANDA, Monika, BACHTIARY, Barbara, SCHWANZELBERGER, Barbara, STOIBER, Alexander, NICKLIN, James L, PERRIN, Lewis C, CRANDON, Lex J

“…In patients undergoing radiation for cervical carcinoma, there is evidence that anemia is associated with an impaired outcome. For patients undergoing…”
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Sequence specificity and reactivity of the binding of phenazine-tethered platinum complexes to DNA by Perrin, L C, Cullinane, C, McFadyen, W D, Phillips, D R

“…An in vitro transcription assay was used to probe the sequence specificity of the binding of phenazine-tethered platinum complexes to DNA. It was found that…”
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Multicomponent NMR Titration for Simultaneous Measurement of Relative pKas by PERRIN, Charles L., FABIAN, Miles A.

“…An NMR titration method has been developed to simultaneously measure the difference in acid dissociation constants (delta pKa) of two or more compounds with…”
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Absence of stereoelectronic control in hydrolysis of cyclic amidines by Perrin, Charles L, Nunez, Oswaldo

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