Search Results - "Perrie, Jennifer A"

Dissecting the reaction of Phase II metabolites of ibuprofen and other NSAIDS with human plasma protein by Monrad, Rune Nygaard, Errey, James C., Barry, Conor S., Iqbal, Mazhar, Meng, Xiaoli, Iddon, Lisa, Perrie, Jennifer A., Harding, John R., Wilson, Ian D., Stachulski, Andrew V., Davis, Benjamin G.

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs on the market. Whilst they are considered safe, several NSAIDs have been…”
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Effective Synthesis of 1β-Acyl Glucuronides by Selective Acylation by Perrie, Jennifer A, Harding, John R, Holt, David W, Johnston, Atholl, Meath, Paul, Stachulski, Andrew V

“…Acyl glucuronides are vital metabolites for many carboxylic acid containing drugs. We report an efficient new method for the chemical synthesis of these…”
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Glucuronidation of steroidal alcohols using iodosugar and imidate donors by Harding, John R, King, Clare D, Perrie, Jennifer A, Sinnott, Deborah, Stachulski, Andrew V

“…We report a study of the glucuronidation of a number of important steroidal secondary alcohols. The alcohols studied are androsterone 7, epiandrosterone 8,…”
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Glycosidation with a Disarmed Glycosyl Iodide:  Promotion and Scope by Perrie, Jennifer A, Harding, John R, King, Clare, Sinnott, Deborah, Stachulski, Andrew V

“…Glucuronyl iodide 1 has been studied in detail as a “disarmed” glycosyl donor. In a model reaction, using N-iodosuccinimide (NIS) as a promoter and…”
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Efficient synthesis of 1β- O-acyl glucuronides via selective acylation of allyl or benzyl d-glucuronate by Bowkett, Elizabeth R., Harding, John R., Maggs, James L., Park, B. Kevin, Perrie, Jennifer A., Stachulski, Andrew V.

“…Acyl glucuronides are key metabolites for many carboxylic acid-containing drugs, notably those of the non-steroidal anti-inflammatory class. In the processes…”
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Dissecting the reaction of Phase II metabolites of ibuprofen and other NSAIDS with human plasma proteinElectronic supplementary information (ESI) available: Additional discussion, experimental methods, raw and processed protein mass spectra as well as mass spectra of tryptic peptides. See DOI: 10.1039/c4sc01329h by Monrad, Rune Nygaard, Errey, James C, Barry, Conor S, Iqbal, Mazhar, Meng, Xiaoli, Iddon, Lisa, Perrie, Jennifer A, Harding, John R, Wilson, Ian D, Stachulski, Andrew V, Davis, Benjamin G

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs on the market. Whilst they are considered safe, several NSAIDs have been…”
Get full text

Effective synthesis of 1beta-acyl glucuronides by selective acylation by Perrie, Jennifer A, Harding, John R, Holt, David W, Johnston, Atholl, Meath, Paul, Stachulski, Andrew V

“…[reaction: see text] Acyl glucuronides are vital metabolites for many carboxylic acid containing drugs. We report an efficient new method for the chemical…”
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