Search Results - "Perretti, M."

Role of the Immune system in chronic pain by McMahon, Stephen B, Marchand, Fabien, Perretti, Mauro

“…During the past two decades, an important focus of pain research has been the study of chronic pain mechanisms, particularly the processes that lead to the…”
Get full text

Annexin‐A1: a pivotal regulator of the innate and adaptive immune systems by D'Acquisto, F, Perretti, M, Flower, R J

“…The glucocorticoids are the most potent anti‐inflammatory drugs that we possess and are effective in a wide variety of diseases. Although their action is known…”
Get full text

Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors by Montero-Melendez, T, Dalli, J, Perretti, M

“…Despite several therapies being currently available to treat inflammatory diseases, new drugs to treat chronic conditions with less side effects and lower…”
Get full text

‘Annexins’ themed section by Flower, R J, Perretti, M

“…Linked Articles This article is part of a themed section on Annexins VII Programme. To view the other articles in this section visit…”
Get full text

Internal Medicine Ward with Hematological Skills for the Treatment of Complications Suffered by Hematological Patients on Therapy: Experience of Villa Betania Hospital in Rome by Andriani, A, Marchetti, L, Rossi, F, Perretti, M A, Raja, S, Recine, U

Get full text

The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil by Sinniah, Ajantha, Yazid, Samia, Perretti, M., Solito, Egle, Flower, R.J.

“…1.We investigated the role of Annexin (ANX)-A1 and its receptor, ALX/FPR2, in the regulation of mast cell degranulation produced by compound 48/80.2.Both human…”
Get full text

Annexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice by Trentin, P G, Ferreira, T P T, Arantes, A C S, Ciambarella, B T, Cordeiro, R S B, Flower, R J, Perretti, M, Martins, M A, Silva, P M R

“…Background and Purpose Endogenous glucocorticoids are pro‐resolving mediators, an example of which is the endogenous glucocorticoid‐regulated protein annexin…”
Get full text

Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy by Franca, Ferraraccio, Trotta, M. C., Getting, S. J., Surace, E., Testa, Francesco, Simonelli, Francesca, Grieco, Paolo, Merlino, Francesco, Perretti, Mauro, D'Amico, Michele, Di Filippo, Clara, Gesualdo, C., Maisto, R., Rossi, S., Kaneva, M. K.

“…We hypothesize that melanocortin receptors (MC) could activate tissue protective circuit in a model of streptozotocin- (STZ-) induced diabetic retinopathy (DR)…”
Get full text

Corrigendum to “Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy” by Rossi, S., Maisto, R., Gesualdo, C., Trotta, M. C., Ferraraccio, F., Kaneva, M. K., Getting, S. J., Surace, E., Testa, F., Simonelli, F., Grieco, P., Merlino, F., Perretti, M., D’Amico, M., Di Filippo, C.

“…[This corrects the article DOI: 10.1155/2016/7368389.].[This corrects the article DOI: 10.1155/2016/7368389.]…”
Get full text

High density micromass cultures of a human chondrocyte cell line: A reliable assay system to reveal the modulatory functions of pharmacological agents by Greco, K.V., Iqbal, A.J., Rattazzi, L., Nalesso, G., Moradi-Bidhendi, N., Moore, A.R., Goldring, M.B., Dell’Accio, F., Perretti, M.

“…Osteoarthritis is a highly prevalent and disabling disease for which we do not have a cure. The identification of suitable molecular targets is hindered by the…”
Get full text

Abstract # 1763 Investigating the Influence of environment and psychological state on the immune response: Developing a PNI toolkit by Brod, S, Gobetti, T, Gittens, B, Perretti, M, D’Acquisto, F

“…Studies have recently demonstrated the immune system to significantly more plastic than previously believed. Multiple external factors have been shown to…”
Get full text

Annexin A1 supplementation prevents the progression to fibrosis of nonalcoholic steatoepatitis (NASH) by Bruzzì, S, Sutti, S, Toscani, A, Bozzola, C, Reutelingsperger, C, Kusters, D, Mcarthur, S, Perretti, M, Albano, E

Get full text

Annexin 1 and neutrophil apoptosis by Perretti, M, Solito, E

“…ANXA1 (annexin 1), a member of the 'annexin' family of calcium- and phospholipid-binding proteins, was originally identified as an endogenous mediator of the…”
Get more information

The role of endogenous annexin A1 (AnxA1) in pregnancy by Moreli, J.B, Hebeda, C.B, Machado, I.D, Reif-Silva, I, Oliani, S.M, Perretti, M, Bevilacqua, E, Farsky, S.H.P

Get full text

Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells by Schutters, K, Kusters, D H M, Chatrou, M L L, Montero-Melendez, T, Donners, M, Deckers, N M, Krysko, D V, Vandenabeele, P, Perretti, M, Schurgers, L J, Reutelingsperger, C P M

“…Impaired efferocytosis has been shown to be associated with, and even to contribute to progression of, chronic inflammatory diseases such as atherosclerosis…”
Get full text

The melanocortin MC 1 receptor agonist BMS‐470539 inhibits leucocyte trafficking in the inflamed vasculature by Leoni, G, Voisin, M‐B, Carlson, K, Getting, SJ, Nourshargh, S, Perretti, M

“…Background and purpose:  Over three decades of research evaluating the biology of melanocortin (MC) hormones and synthetic peptides, activation of the MC type…”
Get full text

The melanocortin MC1 receptor agonist BMS‐470539 inhibits leucocyte trafficking in the inflamed vasculature by Leoni, G, Voisin, M‐B, Carlson, K, Getting, SJ, Nourshargh, S, Perretti, M

“…Background and purpose:  Over three decades of research evaluating the biology of melanocortin (MC) hormones and synthetic peptides, activation of the MC type…”
Get full text

A novel calcium‐dependent proapoptotic effect of annexin 1 on human neutrophils by Solito, Egle, Kamal, Ahmad, Russo-Marie, Francoise, Buckingham, Julia C., Marullo, Stefano, Perretti, Mauro

“…ABSTRACT The glucocorticoid‐inducible protein annexin (ANXA) 1 is an anti‐inflammatory mediator that down‐regulates the host response. Endogenously, ANXA1 is…”
Get full text

Endogenous mediators that inhibit the leukocyte– endothelium interaction by Perretti, M.

“…Leukocyte extravasation occurs in many pathophysiological conditions, including inflammation, neoplasia and asthma. In recent years many studies have…”
Get full text

Microvascular thrombosis and CD40/CD40L signaling by GAVINS, F. N. E., LI, G., RUSSELL, J., PERRETTI, M., GRANGER, D. N.

“…Background: Although inflammation and thrombosis are now recognized to be interdependent processes that activate and perpetuate each other, the signaling…”
Get full text