Search Results - "Perretta, Carin"

Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2 by Nie, Zhe, Perretta, Carin, Erickson, Philip, Margosiak, Stephen, Almassy, Robert, Lu, Jia, Averill, April, Yager, Kraig M., Chu, Shaosong

“…Structure-guided modifications to a series of pyrazolo[1,5-a][1,3,5]triazine derivatives provided pM inhibitors of protein kinase CK2 with low μM cytotoxic…”
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Identification of (3R)-7-Hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)- 3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro- 3-isoquinolinecarboxamide as a Novel Potent and Selective Opioid κ Receptor Antagonist by Thomas, James B, Atkinson, Robert N, Vinson, N. Ariane, Catanzaro, Jennifer L, Perretta, Carin L, Fix, Scott E, Mascarella, S. Wayne, Rothman, Richard B, Xu, Heng, Dersch, Christina M, Cantrell, Buddy E, Zimmerman, Dennis M, Carroll, F. Ivy

“…(3R)-7-Hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic)…”
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Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5- a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities by Nie, Zhe, Perretta, Carin, Erickson, Philip, Margosiak, Stephen, Lu, Jia, Averill, April, Almassy, Robert, Chu, Shaosong

“…A series of macrocyclic derivatives has been designed and synthesized based on the X-ray co-crystal structures of pyrazolo[1,5- a] [1,3,5]triazines with corn…”
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Structure-Based Design, Synthesis, and Study of Potent Inhibitors of β-Ketoacyl-acyl Carrier Protein Synthase III as Potential Antimicrobial Agents by Nie, Zhe, Perretta, Carin, Lu, Jia, Su, Ying, Margosiak, Stephen, Gajiwala, Ketan S, Cortez, Joseph, Nikulin, Victor, Yager, Kraig M, Appelt, Krzysztof, Chu, Shaosong

“…Fatty acid biosynthesis is essential for bacterial survival. Components of this biosynthetic pathway have been identified as attractive targets for the…”
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Identification of (3R)-7-hydroxy-N-((1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)- 3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl)-1,2,3,4-tetrahydro- 3-isoquinolinecarboxamide as a novel potent and selective opioid kappa receptor antagonist by Thomas, James B, Atkinson, Robert N, Vinson, N Ariane, Catanzaro, Jennifer L, Perretta, Carin L, Fix, Scott E, Mascarella, S Wayne, Rothman, Richard B, Xu, Heng, Dersch, Christina M, Cantrell, Buddy E, Zimmerman, Dennis M, Carroll, F Ivy

“…(3R)-7-Hydroxy-N-((1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic)…”
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Identification of (3R)-7-hydroxy-N-((1S)-1-{[(3R, 4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidiny l]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide as a novel potent and selective opioid K receptor antagonist by THOMAS, James B, ATKINSON, Robert N, CANTRELL, Buddy E, ZIMMERMAN, Dennis M, CARROLL, F. Ivy, VINSON, N. Ariane, CATANZARO, Jennifer L, PERRETTA, Carin L, FIX, Scott E, MASCARELLA, S. Wayne, ROTHMAN, Richard B, HENG XU, DERSCH, Christina M

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