Search Results - "Perreau, Victoria"

MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes by Bujalka, Helena, Koenning, Matthias, Jackson, Stacey, Perreau, Victoria M, Pope, Bernard, Hay, Curtis M, Mitew, Stanlislaw, Hill, Andrew F, Lu, Q Richard, Wegner, Michael, Srinivasan, Rajini, Svaren, John, Willingham, Melanie, Barres, Ben A, Emery, Ben

“…The myelination of axons is a crucial step during vertebrate central nervous system (CNS) development, allowing for rapid and energy efficient saltatory…”
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Inflammation in Traumatic Brain Injury: Roles for Toxic A1 Astrocytes and Microglial–Astrocytic Crosstalk by Clark, David P. Q., Perreau, Victoria M., Shultz, Sandy R., Brady, Rhys D., Lei, Enie, Dixit, Shilpi, Taylor, Juliet M., Beart, Philip M., Boon, Wah Chin

“…Traumatic brain injury triggers neuroinflammation that may contribute to progressive neurodegeneration. We investigated patterns of recruitment of astrocytes…”
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Axonal mRNA in Uninjured and Regenerating Cortical Mammalian Axons by Taylor, Anne M, Berchtold, Nicole C, Perreau, Victoria M, Tu, Christina H, Li Jeon, Noo, Cotman, Carl W

“…Using a novel microfluidic chamber that allows the isolation of axons without contamination by nonaxonal material, we have for the first time purified mRNA…”
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Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study by Cribbs, David H, Berchtold, Nicole C, Perreau, Victoria, Coleman, Paul D, Rogers, Joseph, Tenner, Andrea J, Cotman, Carl W

“…This study undertakes a systematic and comprehensive analysis of brain gene expression profiles of immune/inflammation-related genes in aging and Alzheimer's…”
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Voluntary Exercise Decreases Amyloid Load in a Transgenic Model of Alzheimer's Disease by Adlard, Paul A, Perreau, Victoria M, Pop, Viorela, Cotman, Carl W

“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder for which there are few therapeutics that affect the underlying disease mechanism. Recent…”
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Acetylcholine Muscarinic M4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents by Walker, Leigh C., Berizzi, Alice E., Chen, Nicola A., Rueda, Patricia, Perreau, Victoria M., Huckstep, Katherine, Srisontiyakul, Jirawoot, Govitrapong, Piyarat, Xiaojian, Jia, Lindsley, Craig W., Jones, Carrie K., Riddy, Darren M., Christopoulos, Arthur, Langmead, Christopher J., Lawrence, Andrew J.

“…Alcohol use disorder (AUD) is a major socioeconomic burden on society, and current pharmacotherapeutic treatment options are inadequate. Aberrant alcohol use…”
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Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20 by Bahlo, Melanie, Booth, David R, Broadley, Simon A, Brown, Matthew A, Foote, Simon J, Griffiths, Lyn R, Kilpatrick, Trevor J, Lechner-Scott, Jeanette, Moscato, Pablo, Perreau, Victoria M, Rubio, Justin P, Scott, Rodney J, Stankovich, Jim, Stewart, Graeme J, Taylor, Bruce V, Wiley, James, Clarke, Glynnis, Cox, Mathew B, Csurhes, Peter A, Danoy, Patrick, Drysdale, Karen, Field, Judith, Greer, Judith M, Guru, Preethi, Hadler, Johanna, McMorran, Brendan J, Jensen, Cathy J, Johnson, Laura J, McCallum, Ruth, Merriman, Marilyn, Merriman, Tony, Pryce, Karen, Tajouri, Lotfi, Wilkins, Ella J, Browning, Brian L, Browning, Sharon R, Perera, Devindri, Broadley, Simon, Butzkueven, Helmut, Carroll, William M, Chapman, Caron, Kermode, Allan G, Marriott, Mark, Mason, Deborah, Heard, Robert N, Pender, Michael P, Slee, Mark, Tubridy, Niall, Willoughby, Ernest

“…To identify multiple sclerosis (MS) susceptibility loci, we conducted a genome-wide association study (GWAS) in 1,618 cases and used shared data for 3,413…”
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Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse by Heighway, Jacqueline, Sedo, Alicia, Garg, Anjali, Eldershaw, Lauren, Perreau, Victoria, Berecki, Géza, Reid, Christopher A., Petrou, Steven, Maljevic, Snezana

“…Genetic variation in voltage-gated sodium (NaV) channels is a significant contributor to neurodevelopmental disorders. NaV channel alpha subunits are encoded…”
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The exercise-induced expression of BDNF within the hippocampus varies across life-span by Adlard, Paul A., Perreau, Victoria M., Cotman, Carl W.

“…Voluntary exercise increases hippocampal brain-derived neurotrophic factor (BDNF) expression in young animals. In this investigation we examined the induction…”
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Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium by Horvay, Katja, Jardé, Thierry, Casagranda, Franca, Perreau, Victoria M, Haigh, Katharina, Nefzger, Christian M, Akhtar, Reyhan, Gridley, Thomas, Berx, Geert, Haigh, Jody J, Barker, Nick, Polo, Jose M, Hime, Gary R, Abud, Helen E

“…Snail family members regulate epithelial‐to‐mesenchymal transition (EMT) during invasion of intestinal tumours, but their role in normal intestinal homeostasis…”
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Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes by Xu, He, Perreau, Victoria M, Dent, Krista A, Bush, Ashley I, Finkelstein, David I, Adlard, Paul A

“…There is strong evidence that iron homeostasis is impaired in the aging and Alzheimer's disease (AD) brain and that this contributes to neurodegeneration…”
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The minimum information required for reporting a molecular interaction experiment (MIMIx) by Legrain, Pierre, Rivas, Javier De Las, Chatr-aryamontri, Andrew, Mulder, Nicola, Kerrien, Samuel, Bader, Gary D, Cusick, Michael E, Tyers, Mike, Burgoon, Lyle, Oesterheld, Matthias, Greenblatt, Jack, Bader, Joel, Uetz, Peter, Salama, John J, Eisenberg, David, Xenarios, Ioannis, Hogue, Chris, Gavin, Anne-Claude, Cesareni, Gianni, Vidal, Marc, Niepmann, Michael, Gilson, Michael, Armstrong, John, Salwinski, Lukasz, Hermjakob, Henning, Fields, Stan, Mewes, Hans-Werner, Apweiler, Rolf, Orchard, Sandra, Perreau, Victoria M, Ceol, Arnaud, Gerstein, Mark, Superti-Furga, Giulio, Wojcik, Jérôme, Montecchi-Palazzi, Luisa, Woollard, Peter, Moore, Susan, Prieto, Carlos, Stümpflen, Volker

“…A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different…”
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Differential gene expression in the EphA4 knockout spinal cord and analysis of the inflammatory response following spinal cord injury by Munro, Kathryn M, Perreau, Victoria M, Turnley, Ann M

“…Mice lacking the axon guidance molecule EphA4 have been shown to exhibit extensive axonal regeneration and functional recovery following spinal cord injury. To…”
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Computational deconvolution of genome wide expression data from Parkinson's and Huntington's disease brain tissues using population-specific expression analysis by Capurro, Alberto, Bodea, Liviu-Gabriel, Schaefer, Patrick, Luthi-Carter, Ruth, Perreau, Victoria M

“…The characterization of molecular changes in diseased tissues gives insight into pathophysiological mechanisms and is important for therapeutic development…”
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Identity-by-descent mapping to detect rare variants conferring susceptibility to multiple sclerosis by Lin, Rui, Charlesworth, Jac, Stankovich, Jim, Perreau, Victoria M, Brown, Matthew A, Taylor, Bruce V

“…Genome-wide association studies (GWAS) have identified around 60 common variants associated with multiple sclerosis (MS), but these loci only explain a…”
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Short-Term Environmental Stimulation Spatiotemporally Modulates Specific Serotonin Receptor Gene Expression and Behavioral Pharmacology in a Sexually Dimorphic Manner in Huntington's Disease Transgenic Mice by Zajac, Michelle S, Renoir, Thibault, Perreau, Victoria M, Li, Shanshan, Adams, Wendy, van den Buuse, Maarten, Hannan, Anthony J

“…Huntington's disease (HD) is a neurodegenerative disorder caused by a tandem repeat mutation encoding an expanded polyglutamine tract in the huntingtin…”
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The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise by Adlard, Paul A., Perreau, Victoria M., Engesser-Cesar, Christie, Cotman, Carl W.

“…In this study we examined the timecourse of induction of brain-derived neurotrophic factor (BDNF) mRNA and protein after 1, 3, 5, 7, 14 and 28 days of exercise…”
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Modulation of bone morphogenic protein signalling alters numbers of astrocytes and oligodendroglia in the subventricular zone during cuprizone-induced demyelination by Cate, Holly S, Sabo, Jennifer K, Merlo, Daniel, Kemper, Dennis, Aumann, Tim D, Robinson, Julien, Merson, Toby D, Emery, Ben, Perreau, Victoria M, Kilpatrick, Trevor J

“…J. Neurochem. (2010) 115, 11-22. The adult subventricular zone (SVZ) is a potential source of precursor cells to replace neural cells lost during…”
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Effects of Exercise on Gene-Expression Profile in the Rat Hippocampus by Tong, Liqi, Shen, Hong, Perreau, Victoria M., Balazs, Robert, Cotman, Carl W.

“…Exercise has beneficial effects on brain function, including the promotion of plasticity and the enhancement of learning and memory performance. Previously we…”
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Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor Fasudil reveals cytoskeletal and pro-survival responses by Lau, Chew L., Perreau, Victoria M., Chen, Minghui J., Cate, Holly S., Merlo, Daniel, Cheung, Nam S., O'Shea, Ross D., Beart, Philip M.

“…Inhibitors of Rho kinase (ROCK) have potential for management of neurological disorders by inhibition of glial scarring. Since astrocytes play key roles in…”
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