Search Results - "Perreau, Matthieu"
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The cytokines HGF and CXCL13 predict the severity and the mortality in COVID-19 patients
Published in Nature communications (09-08-2021)“…The objective of the present study was to identify biological signatures of severe coronavirus disease 2019 (COVID-19) predictive of admission in the intensive…”
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Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells
Published in PLoS pathogens (05-07-2022)“…The limited development of broadly neutralizing antibodies (BnAbs) during HIV infection is classically attributed to an inadequate B-cell help brought by…”
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Editorial: Understanding convergent evasion mechanisms in cancer and chronic infection: implications for immunotherapy
Published in Frontiers in immunology (01-07-2024)Get full text
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Host Molecule Incorporation into HIV Virions, Potential Influences in HIV Pathogenesis
Published in Viruses (01-11-2022)“…During the last phase of HIV viral production, nascent HIV virions acquire a fraction of the cellular lipid membrane to create the external lipid envelope, a…”
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Real-life drug retention rate and safety of rituximab when treating rheumatic diseases: a single-centre Swiss retrospective cohort study
Published in Arthritis research & therapy (01-06-2023)“…In Switzerland, rituximab (RTX) is licenced for the treatment of rheumatoid arthritis (RA) and ANCA-associated vasculitis (AAV) but is frequently used…”
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Cancer and HIV-1 Infection: Patterns of Chronic Antigen Exposure
Published in Frontiers in immunology (30-06-2020)“…The main role of the human immune system is to eliminate cells presenting foreign antigens and abnormal patterns, while maintaining self-tolerance. However,…”
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Heterogenous humoral and cellular immune responses with distinct trajectories post-SARS-CoV-2 infection in a population-based cohort
Published in Nature communications (18-08-2022)“…To better understand the development of SARS-CoV-2-specific immunity over time, a detailed evaluation of humoral and cellular responses is required. Here, we…”
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CD160-associated CD8 T-cell functional impairment is independent of PD-1 expression
Published in PLoS pathogens (01-09-2014)“…Expression of co-inhibitory molecules is generally associated with T-cell dysfunction in chronic viral infections such as HIV or HCV. However, their relative…”
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Basophil activation tests with cryopreserved mRNA-based COVID-19 vaccines
Published in Allergology international (01-10-2023)Get full text
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10
Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells
Published in PLoS pathogens (01-09-2016)“…Human adenoviruses (HAdVs) are nonenveloped proteinaceous particles containing a linear double-stranded DNA genome. HAdVs cause a spectrum of pathologies in…”
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Estradiol and Progesterone Strongly Inhibit the Innate Immune Response of Mononuclear Cells in Newborns
Published in Infection and Immunity (01-07-2011)“…Newborns are particularly susceptible to bacterial infections due to qualitative and quantitative deficiencies of the neonatal innate immune system. However,…”
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RAIN: machine learning-based identification for HIV-1 bNAbs
Published in Nature communications (24-06-2024)“…Broadly neutralizing antibodies (bNAbs) are promising candidates for the treatment and prevention of HIV-1 infections. Despite their critical importance,…”
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Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen
Published in PLoS pathogens (08-08-2024)“…The pathogenesis of HIV-1 infection is governed by a highly dynamic, time-dependent interaction between the host and the viral genome. In this study, we…”
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CD177, a specific marker of neutrophil activation, is associated with coronavirus disease 2019 severity and death
Published in iScience (23-07-2021)“…The identification of patients with coronavirus disease 2019 and high risk of severe disease is a challenge in routine care. We performed cell phenotypic,…”
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CXCL12 and CXCL13 Cytokine Serum Levels Are Associated with the Magnitude and the Quality of SARS-CoV-2 Humoral Responses
Published in Viruses (28-11-2022)“…A better understanding of the immunological markers associated with long-lasting immune responses to SARS-CoV-2 infection is of paramount importance. In the…”
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IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns
Published in Frontiers in immunology (11-07-2018)“…Infections are a leading cause of mortality and morbidity in newborns. The high susceptibility of newborns to infection has been associated with a limited…”
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Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement
Published in PLoS pathogens (01-07-2019)“…T-follicular helper (Tfh) cells, co-expressing PD-1 and TIGIT, serve as a major cell reservoir for HIV-1 and are responsible for active and persistent HIV-1…”
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Blood CXCR3 + CD4 T Cells Are Enriched in Inducible Replication Competent HIV in Aviremic Antiretroviral Therapy-Treated Individuals
Published in Frontiers in immunology (05-02-2018)“…We recently demonstrated that lymph nodes (LNs) PD-1 /T follicular helper (Tfh) cells from antiretroviral therapy (ART)-treated HIV-infected individuals were…”
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Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells
Published in PLoS pathogens (01-08-2018)“…Following repeated encounters with adenoviruses most of us develop robust humoral and cellular immune responses that are thought to act together to combat…”
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IL-17 receptor A and adenosine deaminase 2 deficiency in siblings with recurrent infections and chronic inflammation
Published in Journal of allergy and clinical immunology (01-04-2016)“…Background Data on patients affected by chronic mucocutaneous candidiasis underscore the preponderant role of IL-17 receptor A (IL-17RA) in preserving…”
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