Search Results - "Perrat, Paola"
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Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
Published in Science (American Association for the Advancement of Science) (05-04-2013)“…Recent studies in mammals have documented the neural expression and mobility of retrotransposons and have suggested that neural genomes are diverse mosaics. We…”
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Glypican Is a Modulator of Netrin-Mediated Axon Guidance
Published in PLoS biology (01-07-2015)“…Netrin is a key axon guidance cue that orients axon growth during neural circuit formation. However, the mechanisms regulating netrin and its receptors in the…”
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3
Memory-Relevant Mushroom Body Output Synapses Are Cholinergic
Published in Neuron (Cambridge, Mass.) (16-03-2016)“…Memories are stored in the fan-out fan-in neural architectures of the mammalian cerebellum and hippocampus and the insect mushroom bodies. However, whereas key…”
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Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans
Published in PLoS genetics (09-01-2017)“…The regulation of cell migration is essential to animal development and physiology. Heparan sulfate proteoglycans shape the interactions of morphogens and…”
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The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans
Published in PLoS genetics (22-01-2019)“…Nuclear hormone receptors (NHRs) are ligand-gated transcription factors that control adaptive host responses following recognition of specific endogenous or…”
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Cbfβ-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia
Published in Cancer cell (2006)“…The acute myeloid leukemia (AML)-associated CBFβ-SMMHC fusion protein impairs hematopoietic differentiation and predisposes to leukemic transformation. The…”
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Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11
Published in Blood (01-04-2005)“…Recurrent chromosomal rearrangements are associated with the development of acute myeloid leukemia (AML). The frequent inversion of chromosome 16 creates the…”
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8
There are many ways to train a fly
Published in Fly (Austin, Tex.) (01-01-2009)“…A biological understanding of memory remains one of the great quests of neuroscience. For over 30 years the fruit fly Drosophila melanogaster has primarily…”
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Diverse Odor-Conditioned Memories Require Uniquely Timed Dorsal Paired Medial Neuron Output
Published in Neuron (Cambridge, Mass.) (28-10-2004)“…amnesiac mutant flies have an olfactory memory defect. The amn gene encodes a homolog of vertebrate pituitary adenylate cyclase-activating peptide (PACAP), and…”
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Neuronal postdevelopmentally acting SAX-7S/L1CAM can function as cleaved fragments to maintain neuronal architecture in Caenorhabditis elegans
Published in Genetics (Austin) (09-08-2021)“…Abstract Whereas remarkable advances have uncovered mechanisms that drive nervous system assembly, the processes responsible for the lifelong maintenance of…”
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202.1: Pancreatic islets from genetically altered porcine donors are metabolically competent and cure diabetes in mice post xenotransplantation
Published in Transplantation (01-10-2023)Get full text
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Glypican Is a Modulator of Netrin-Mediated Axon Guidance: e1002183
Published in PLoS biology (01-07-2015)“…Netrin is a key axon guidance cue that orients axon growth during neural circuit formation. However, the mechanisms regulating netrin and its receptors in the…”
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13
Plag1 and Plag12 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11
Published in Blood (2005)Get full text
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