Search Results - "Perosky, Joseph E."

Abnormal type I collagen post-translational modification and crosslinking in a cyclophilin B KO mouse model of recessive osteogenesis imperfecta by Cabral, Wayne A, Perdivara, Irina, Weis, MaryAnn, Terajima, Masahiko, Blissett, Angela R, Chang, Weizhong, Perosky, Joseph E, Makareeva, Elena N, Mertz, Edward L, Leikin, Sergey, Tomer, Kenneth B, Kozloff, Kenneth M, Eyre, David R, Yamauchi, Mitsuo, Marini, Joan C

“…Cyclophilin B (CyPB), encoded by PPIB, is an ER-resident peptidyl-prolyl cis-trans isomerase (PPIase) that functions independently and as a component of the…”
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Characterization of bone microstructure using photoacoustic spectrum analysis by Feng, Ting, Perosky, Joseph E, Kozloff, Kenneth M, Xu, Guan, Cheng, Qian, Du, Sidan, Yuan, Jie, Deng, Cheri X, Wang, Xueding

“…Osteoporosis is a progressive bone disease that is characterized by a decrease in bone mass and the deterioration in bone microarchitecture. This study…”
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Maternity waiting homes in Liberia: Results of a countrywide multi-sector scale-up by Lori, Jody R, Perosky, Joseph E, Rominski, Sarah, Munro-Kramer, Michelle L, Cooper, Faith, Kofa, Alphonso, Nyanplu, Aloysius, James, Katherine H, Cole, G. Gorma, Coley, Katrina, Liu, Haiyin, Moyer, Cheryl A

“…Objective Descriptions of maternity waiting homes (MWHs) as an intervention to increase facility delivery for women living in remote geographic areas dates…”
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Bone assessment via thermal photo-acoustic measurements by Feng, Ting, Kozloff, Kenneth M, Tian, Chao, Perosky, Joseph E, Hsiao, Yi-Sing, Du, Sidan, Yuan, Jie, Deng, Cheri X, Wang, Xueding

“…The feasibility of an innovative biomedical diagnostic technique, thermal photo-acoustic (TPA) measurement, for non-ionizing and non-invasive assessment of…”
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Comparison of quality, birth outcomes, and service utilization between health facilities with and without maternity waiting homes in Liberia by Horton, Rachel, Lee, Haeun, Perosky, Joseph E., Kofa, Alphonso, Lori, Jody R.

“…1) To assess the quality of health facilities associated with functional Maternity Waiting Homes and health facilities without functional maternity waiting…”
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Maternity waiting homes as an intervention to increase facility delivery in rural Zambia by Perosky, Joseph E., Munro‐Kramer, Michelle L., Lockhart, Nancy, Musonda, Gertrude K., Naggayi, Anne, Lori, Jody R.

“…This study indicates a higher rate of facility delivery at clinics with a maternity waiting home in rural Zambia…”
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Early detection of burn induced heterotopic ossification using transcutaneous Raman spectroscopy by Peterson, Jonathan R, Okagbare, Paul I, De La Rosa, Sara, Cilwa, Katherine E, Perosky, Joseph E, Eboda, Oluwatobi N, Donneys, Alexis, Su, Grace L, Buchman, Steven R, Cederna, Paul S, Wang, Stewart C, Kozloff, Kenneth M, Morris, Michael D, Levi, Benjamin

“…Abstract Introduction Heterotopic ossification (HO), or the abnormal formation of bone in soft tissue, occurs in over 60% of major burn injuries and blast…”
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Substitution of murine type I collagen A1 3-hydroxylation site alters matrix structure but does not recapitulate osteogenesis imperfecta bone dysplasia by Cabral, Wayne A., Fratzl-Zelman, Nadja, Weis, MaryAnn, Perosky, Joseph E., Alimasa, Adrienne, Harris, Rachel, Kang, Heeseog, Makareeva, Elena, Barnes, Aileen M., Roschger, Paul, Leikin, Sergey, Klaushofer, Klaus, Forlino, Antonella, Backlund, Peter S., Eyre, David R., Kozloff, Kenneth M., Marini, Joan C.

“…Null mutations in CRTAP or P3H1, encoding cartilage-associated protein and prolyl 3-hydroxylase 1, cause the severe bone dysplasias, types VII and VIII…”
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Single dose of bisphosphonate preserves gains in bone mass following cessation of sclerostin antibody in Brtl/+ osteogenesis imperfecta model by Perosky, Joseph E., Khoury, Basma M., Jenks, Terese N., Ward, Ferrous S., Cortright, Kai, Meyer, Bethany, Barton, David K., Sinder, Benjamin P., Marini, Joan C., Caird, Michelle S., Kozloff, Kenneth M.

“…Sclerostin antibody has demonstrated a bone-forming effect in pre-clinical models of osteogenesis imperfecta, where mutations in collagen or…”
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Deferoxamine Restores Callus Size, Mineralization, and Mechanical Strength in Fracture Healing after Radiotherapy by Donneys, Alexis, Ahsan, Salman, Perosky, Joseph E., Deshpande, Sagar S., Tchanque-Fossuo, Catherine N., Levi, Benjamin, Kozloff, Ken M., Buchman, Steven R.

“…Therapeutic augmentation of fracture-site angiogenesis with deferoxamine has proven to increase vascularity, callus size, and mineralization in long-bone…”
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Early detection of heterotopic ossification using near-infrared optical imaging reveals dynamic turnover and progression of mineralization following Achilles tenotomy and burn injury by Perosky, Joseph E., Peterson, Jonathan R., Eboda, Owulatobi N., Morris, Michael D., Wang, Stewart C., Levi, Benjamin, Kozloff, Kenneth M.

“…ABSTRACT Heterotopic ossification (HO) is the abnormal formation of bone in soft tissue. Current diagnostics have low sensitivity or specificity to incremental…”
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Type III collagen modulates fracture callus bone formation and early remodeling by Miedel, Emily L., Brisson, Becky K., Hamilton, Todd, Gleason, Hadley, Swain, Gary P., Lopas, Luke, Dopkin, Derek, Perosky, Joseph E., Kozloff, Kenneth M., Hankenson, Kurt D., Volk, Susan W.

“…ABSTRACT Type III collagen (Col3) has been proposed to play a key role in tissue repair based upon its temporospatial expression during the healing process of…”
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Acceptability and feasibility of insect consumption among pregnant women in Liberia by Coley, Katrina M., Perosky, Joseph E., Nyanplu, Aloysius, Kofa, Alphonso, Anankware, Jacob P., Moyer, Cheryl A., Lori, Jody R.

“…Maternity waiting homes (MWHs) in Liberia promote facility‐based delivery to reduce maternal mortality. However, women often must bring their own food and…”
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Deferoxamine expedites consolidation during mandibular distraction osteogenesis by Donneys, Alexis, Deshpande, Sagar S, Tchanque-Fossuo, Catherine N, Johnson, Kelsey L, Blough, Jordan T, Perosky, Joseph E, Kozloff, Kenneth M, Felice, Peter A, Nelson, Noah S, Farberg, Aaron S, Levi, Benjamin, Buchman, Steven R

“…Abstract Background A limitation of mandibular distraction osteogenesis (DO) is the length of time required for consolidation. This drawback subjects patients…”
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Thrombospondin-2 deficiency in growing mice alters bone collagen ultrastructure and leads to a brittle bone phenotype by Manley, Jr, Eugene, Perosky, Joseph E, Khoury, Basma M, Reddy, Anita B, Kozloff, Kenneth M, Alford, Andrea I

“…Thrombospondin-2 (TSP2) is a matricellular protein component of the bone extracellular matrix. Long bones of adult TSP2-deficient mice have increased endosteal…”
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Prevention of radiation-induced bone pathology through combined pharmacologic cytoprotection and angiogenic stimulation by Donneys, Alexis, Nelson, Noah S, Perosky, Joseph E, Polyatskaya, Yekaterina, Rodriguez, Jose J, Figueredo, Christian, Vasseli, Cheyenne A, Ratliff, Hannah C, Deshpande, Sagar S, Kozloff, Kenneth M, Buchman, Steven R

“…Abstract Pathologic fractures and associated non-unions arising in previously irradiated bone are severely debilitating diseases. Although radiation is known…”
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A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type by Geister, Krista A, Brinkmeier, Michelle L, Hsieh, Minnie, Faust, Susan M, Karolyi, I Jill, Perosky, Joseph E, Kozloff, Kenneth M, Conti, Marco, Camper, Sally A

“…We discovered a new spontaneous mutant allele of Npr2 named peewee (pwe) that exhibits severe disproportionate dwarfism and female infertility. The pwe…”
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A case series study on the effect of Ebola on facility-based deliveries in rural Liberia by Lori, Jody R, Rominski, Sarah Danielson, Perosky, Joseph E, Munro, Michelle L, Williams, Garfee, Bell, Sue Anne, Nyanplu, Aloysius B, Amarah, Patricia N M, Boyd, Carol J

“…As communities' fears of Ebola virus disease (EVD) in West Africa exacerbate and their trust in healthcare providers diminishes, EVD has the potential to…”
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Nonvascularized Bone Graft Reconstruction of the Irradiated Murine Mandible: An Analogue of Clinical Head and Neck Cancer Treatment by Urlaub, Kevin M, Ettinger, Russell E, Nelson, Noah S, Hoxie, Jessie M, Snider, Alicia E, Perosky, Joseph E, Polyatskaya, Yekaterina, Donneys, Alexis, Buchman, Steven R

“…Nonvascularized bone grafts (NBGs) represent a practical method of mandibular reconstruction that is precluded in head and neck cancer patients by the…”
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Utilization of maternity waiting homes: before, during, and after the Ebola virus disease outbreak in Bong County, Liberia by Perosky, Joseph E, McLean, Karina Z, Kofa, Alphonso, Nyanplu, Aloysius, Munro-Kramer, Michelle L, Lori, Jody R

“…Abstract Background Maternity waiting homes (MWHs) are used to increase the number of women delivering at health care facilities. The first MWHs in Liberia…”
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