Search Results - "Peroni, Roxana N."
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Development and Validation of a Computational Model Ensemble for the Early Detection of BCRP/ABCG2 Substrates during the Drug Design Stage
Published in Journal of chemical information and modeling (28-08-2017)“…Breast Cancer Resistance Protein (BCRP) is an ATP-dependent efflux transporter linked to the multidrug resistance phenomenon in many diseases such as epilepsy…”
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Phytoestrogens Enhance the Vascular Actions of the Endocannabinoid Anandamide in Mesenteric Beds of Female Rats
Published in International Journal of Hypertension (01-01-2012)“…In rat isolated mesenteric beds that were contracted with NA as an in vitro model of the vascular adrenergic hyperactivity that usually precedes the onset of…”
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3
Modulation of hepatic ABC transporters by Eruca vesicaria intake: Potential diet-drug interactions
Published in Food and chemical toxicology (01-11-2019)“…The aim of this work was to evaluate whether oral administration of Eruca vesicaria, a species of rocket cultivated in Argentina, could modify cyclophosphamide…”
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4
Efavirenz is a substrate and in turn modulates the expression of the efflux transporter ABCG2/BCRP in the gastrointestinal tract of the rat
Published in Biochemical pharmacology (01-11-2011)“…The oral bioavailability of the antiretroviral efavirenz (EFV) undergoes high inter and intra-individual variability, this fact supporting its therapeutic drug…”
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In vivo antigenotoxic activity of Diplotaxis tenuifolia against cyclophosphamide-induced DNA damage: Relevance of modulation of hepatic ABC efflux transporters
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-12-2018)“…•Diplotaxis tenuifolia juice is not genotoxic in vivo.•Chronic intake of Diplotaxis tenuifolia can prevent damage by cyclophosphamide.•Diplotaxis tenuifolia…”
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Tetronic® 904-containing polymeric micelles overcome the overexpression of ABCG2 in the blood-brain barrier of rats and boost the penetration of the antiretroviral efavirenz into the CNS
Published in Nanomedicine (London, England) (01-08-2015)“…To assess the involvement of ABCG2 in the pharmacokinetics of efavirenz in the blood-brain barrier (BBB) and investigate a nanotechnology strategy to overcome…”
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7
Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats
Published in European journal of pharmacology (02-07-2007)“…The aim of the present study was to determine whether the transient receptor potential vanilloid (TRPV1) receptor protein as well as the calcitonin…”
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Participation of CGRP and prostanoids in the sex-linked differences of vascular anandamide effects in mesenteric beds of Sprague-Dawley rats
Published in European journal of pharmacology (14-02-2007)“…The in vitro exposure to anandamide elicits greater relaxations in mesenteric beds isolated from female compared to male rats. The present work shows that in…”
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9
Sex-linked differences in the vasorelaxant effects of anandamide in vascular mesenteric beds: role of oestrogens
Published in European journal of pharmacology (16-06-2004)“…Anandamide (0.01 to 10 μM) caused greater concentration-dependent reductions of the contractile-induced responses to noradrenaline in female than in male…”
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Tetronic.sup.[R] 904-containing polymeric micelles overcome the overexpression of ABCG2 in the blood-brain barrier of rats and boost the penetration of the antiretroviral efavirenz into the CNS
Published in Nanomedicine (London, England) (01-08-2015)“…Aim: To assess the involvement of ABCG2 in the pharmacokinetics of efavirenz in the blood-brain barrier (BBB) and investigate a nanotechnology strategy to…”
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11
Tetronic registered 904-containing polymeric micelles overcome the overexpression of ABCG2 in the blood-brain barrier of rats and boost the penetration of the antiretroviral efavirenz into the CNS
Published in Nanomedicine (London, England) (01-08-2015)“…Aim: To assess the involvement of ABCG2 in the pharmacokinetics of efavirenz in the blood-brain barrier (BBB) and investigate a nanotechnology strategy to…”
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12
Tetronic
Published in Nanomedicine (London, England) (01-08-2015)“…To assess the involvement of ABCG2 in the pharmacokinetics of efavirenz in the blood-brain barrier (BBB) and investigate a nanotechnology strategy to overcome…”
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