Search Results - "Peroni, Cibele N"

N-Glycoprofiling Analysis for Carbohydrate Composition and Site-Occupancy Determination in a Poly-Glycosylated Protein: Human Thyrotropin of Different Origins by Ribela, Maria Teresa C P, Damiani, Renata, Silva, Felipe D, Lima, Eliana R, Oliveira, João E, Peroni, Cibele N, Torjesen, Peter A, Soares, Carlos R, Bartolini, Paolo

“…Human thyrotropin (hTSH) is a glycoprotein with three potential glycosylation sites: two in the α-subunit and one in the β-subunit. These sites are not always…”
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A novel homologous model for gene therapy of dwarfism by non-viral transfer of the mouse growth hormone gene into immunocompetent dwarf mice by Cecchi, Claudia R, Higuti, Eliza, Oliveira, Nelio A J, Lima, Eliana R, Jakobsen, Maria, Dagnaes-Hansen, Frederick, Gissel, Hanne, Aagaard, Lars, Jensen, Thomas G, Jorge, Alexander A L, Bartolini, Paolo, Peroni, Cibele N

“…The possibilities for non-viral GH gene therapy are studied in immunocompetent dwarf mice (lit/lit). As expression vector we used a plasmid previously employed…”
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Growth responses following a single intra-muscular hGH plasmid administration compared to daily injections of hGH in dwarf mice by Higuti, Eliza, Cecchi, Claudia R, Oliveira, Nelio A J, Vieira, Daniel P, Jensen, Thomas G, Jorge, Alexander A L, Bartolini, Paolo, Peroni, Cibele N

“…In previous work, sustained levels of circulating human growth hormone (hGH) and a highly significant weight increase were observed after electrotransfer of…”
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Growth Hormone Receptor Deletion Reduces the Density of Axonal Projections from Hypothalamic Arcuate Nucleus Neurons by Wasinski, Frederick, Furigo, Isadora C., Teixeira, Pryscila D.S., Ramos-Lobo, Angela M., Peroni, Cibele N., Bartolini, Paolo, List, Edward O., Kopchick, John J., Donato, Jose

“…•Formation of POMC and AgRP projections requires GH and leptin signaling.•POMC and AgRP projections are affected by LepR-specific GH receptor disruption.•AgRP…”
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Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice by Peroni, Cibele N., Hayashida, Cesar Y., Nascimento, Nancy, Longuini, Viviane C., Toledo, Rodrigo A., Bartolini, Paolo, Bowers, Cyril Y., Toledo, Sergio P.A.

“…To investigate a possible direct, growth hormone-releasing, hormone-independent action of a growth hormone secretagogue, GHRP-2, in pituitary somatotroph cells…”
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The Pattern of GH Action in the Mouse Brain by Menezes, Filipe, Wasinski, Frederick, de Souza, Gabriel O, Nunes, Amanda P, Bernardes, Emerson S, dos Santos, Sofia N, da Silva, Fábio F A, Peroni, Cibele N, Oliveira, João E, Kopchick, John J, Brown, Rosemary S E, Fernandez, Gimena, De Francesco, Pablo N, Perelló, Mario, Soares, Carlos R J, Donato, Jose

“…Abstract GH acts in numerous organs expressing the GH receptor (GHR), including the brain. However, the mechanisms behind the brain's permeability to GH and…”
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Brain STAT5 signaling modulates learning and memory formation by Furigo, Isadora C., Melo, Helen M., Lyra e Silva, Natalia M., Ramos-Lobo, Angela M., Teixeira, Pryscila D. S., Buonfiglio, Daniella C., Wasinski, Frederick, Lima, Eliana R., Higuti, Eliza, Peroni, Cibele N., Bartolini, Paolo, Soares, Carlos R. J., Metzger, Martin, de Felice, Fernanda G., Donato, Jose

“…The signal transducer and activator of transcription 5 (STAT5) is a transcription factor recruited by numerous cytokines. STAT5 is important for several…”
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Sustained secretion of human growth hormone from TheraCyte devices encapsulated with PiggyBac-engineered retinal pigment epithelium cells by Cecchi, Claudia R., Alsing, Sidsel, Jesus, Gustavo P.P., Zacarias, Enio A., Kjaer, Lisbeth, Clement, Michelle S., Kumagai-Braesch, Makiko, Corydon, Thomas J., Bartolini, Paolo, Peroni, Cibele N., Aagaard, Lars

“…Growth hormone (GH) deficiency is characterized by impaired growth and development, and is currently treated by repeated administration of recombinant human GH…”
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Determination of Chinese hamster ovary cell-derived recombinant thyrotropin by reversed-phase liquid chromatography by de Oliveira, João Ezequiel, de Mendonça, Fernanda, Peroni, Cibele N, Bartolini, Paolo, Ribela, Maria Teresa C.P

“…A reversed-phase high-performance liquid chromatography (RP-HPLC) methodology for the qualitative and quantitative analysis of human thyrotropin (hTSH) in CHO…”
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Partial correction of the dwarf phenotype by non-viral transfer of the growth hormone gene in mice: Treatment age is critical by Higuti, Eliza, Cecchi, Cláudia R, Oliveira, Nélio A.J, Lima, Eliana R, Vieira, Daniel P, Aagaard, Lars, Jensen, Thomas G, Jorge, Alexander A.L, Bartolini, Paolo, Peroni, Cibele N

“…Abstract Non-viral transfer of the growth hormone gene to different muscles of immunodeficient dwarf (lit/scid) mice is under study with the objective of…”
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High-level expression of human thyroid-stimulating hormone in Chinese hamster ovary cells by co-transfection of dicistronic expression vectors followed by a dual-marker amplification strategy by Peroni, Cibele N., Soares, Carlos R. J., Gimbo, Elizabeth, Morganti, Ligia, Ribela, Maria Teresa C.P., Bartolini, Paolo

“…The utilization of dicistronic mRNA expression vectors, containing the gene of interest upstream of an amplifiable marker gene, has shown success in rapidly,…”
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Long-term human growth hormone expression and partial phenotypic correction by plasmid-based gene therapy in an animal model of isolated growth hormone deficiency by Oliveira, Nélio A. J., Cecchi, Cláudia R., Higuti, Eliza, Oliveira, João E., Jensen, Thomas G., Bartolini, Paolo, Peroni, Cibele N.

“…Background A model for in vivo gene therapy based on electroporation of human growth hormone (hGH)‐coding naked DNA in the muscle of dwarf (lit/lit) and…”
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Improved Bioprocess with CHO-hTSH Cells on Higher Microcarrier Concentration Provides Higher Overall Biomass and Productivity for rhTSH by Ventini, Daniella C., Damiani, Renata, Sousa, Alvaro P. B., de Oliveira, João E., Peroni, Cibele N., Ribela, Maria T. C. P., Bartolini, Paolo, Tonso, Aldo, Soares, Carlos R. J., Pereira, Carlos A.

“…Since the recombinant thyroid-stimulating hormone (rhTSH) is secreted by stably transfected Chinese hamster ovary (CHO-hTSH) cells, a bioprocess consisting of…”
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Animal models for growth hormone gene therapy by Peroni, Cibele N, Gout, Peter W, Bartolini, Paolo

“…Treatment of growth hormone (GH) deficiency via parenteral administration of recombinant hGH has greatly benefited from recombinant DNA technology allowing…”
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High-yield purification of biosynthetic human growth hormone secreted in Escherichia coli periplasmic space by de Oliveira, João Ezequiel, Soares, Carlos R.J, Peroni, Cibele N, Gimbo, Elizabeth, Camargo, Iara M.C, Morganti, Ligia, Bellini, Maria Helena, Affonso, Regina, Arkaten, Rosangela R, Bartolini, Paolo, Ribela, Maria Teresa C.P

“…A six-step, high-yield purification procedure for the preparation of clinical grade recombinant human growth hormone (rhGH) secreted in bacterial periplasmic…”
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Carbohydrate composition and site-occupancy determination in pituitary and recombinant preparations of human thyrotropin by Bartolini, Paolo, Ribela, Maria Teresa Cp, Damiani, Renata, Silva, Felipe D., Lima, Eliana R., Oliveira, João E., Peroni, Cibele N., Torjesen, Peter A., Soares, Carlos R.

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178. Early Treatment for Growth Hormone Deficiency Based on Naked DNA Administration in Dwarf Mice Allows Efficient Catch-Up Growth by Higuti, Eliza, Cecchi, Claudia R., Lima, Eliana R., Aagaard, Lars, Jensen, Thomas G., Bartolini, Paolo, Peroni, Cibele N.

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Analysis and characterization of different preparations of recombinant human follicle stimulating hormone (hFSH) and of its subunits by Ribela, Maria, Loureiro, Renan, Oliveira, João, Carvalho, Cristiane, Peroni, Cibele, Bartolini, Paolo

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Sensitive human thyrotropin immunoradiometric assay set up by the identification and minimization of nonspecific bindings by Peroni, C N, Ribela, M T, Bartolini, P

“…An immunoradiometric assay (IRMA) of human thyrotropin (hTSH), based on magnetic solid phase separation, was studied especially in terms of its nonspecific…”
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