Search Results - "Pernet‐Gallay, Karin"

SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes by Kherraf, Zine‐Eddine, Christou‐Kent, Marie, Karaouzene, Thomas, Amiri‐Yekta, Amir, Martinez, Guillaume, Vargas, Alexandra S, Lambert, Emeline, Borel, Christelle, Dorphin, Béatrice, Aknin‐Seifer, Isabelle, Mitchell, Michael J, Metzler‐Guillemain, Catherine, Escoffier, Jessica, Nef, Serge, Grepillat, Mariane, Thierry‐Mieg, Nicolas, Satre, Véronique, Bailly, Marc, Boitrelle, Florence, Pernet‐Gallay, Karin, Hennebicq, Sylviane, Fauré, Julien, Bottari, Serge P, Coutton, Charles, Ray, Pierre F, Arnoult, Christophe

“…Azoospermia, characterized by the absence of spermatozoa in the ejaculate, is a common cause of male infertility with a poorly characterized etiology. Exome…”
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Photoactivation of gold nanoparticles for glioma treatment by Bobyk, Laure, PhD, Edouard, Magali, PhD, Deman, Pierre, PhD, Vautrin, Mathias, PhD, Pernet-Gallay, Karin, PhD, Delaroche, Julie, Adam, Jean-François, PhD, Estève, François, MD, PhD, Ravanat, Jean-Luc, PhD, Elleaume, Hélène, PhD

“…Abstract Radiosensitization efficacy of gold nanoparticles (AuNPs) with low energy radiations (88 keV) was evaluated in vitro and in vivo on rats bearing…”
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Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of huntingtin by Bruyère, Julie, Abada, Yah-Se, Vitet, Hélène, Fontaine, Gaëlle, Deloulme, Jean-Christophe, Cès, Aurélia, Denarier, Eric, Pernet-Gallay, Karin, Andrieux, Annie, Humbert, Sandrine, Potier, Marie-Claude, Delatour, Benoît, Saudou, Frédéric

“…Studies have suggested that amyloid precursor protein (APP) regulates synaptic homeostasis, but the evidence has not been consistent. In particular, signaling…”
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Cryo-FIB-SEM as a promising tool for localizing proteins in 3D by Spehner, Daniele, Steyer, Anna M., Bertinetti, Luca, Orlov, Igor, Benoit, Lucas, Pernet-Gallay, Karin, Schertel, Andreas, Schultz, Patrick

“…[Display omitted] Focused Ion Beam-Scanning Electron Microscopy (FIB-SEM) is an invaluable tool to visualize the 3D architecture of cell constituents and map…”
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Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity by Lachenal, Gaelle, Pernet-Gallay, Karin, Chivet, Mathilde, Hemming, Fiona J., Belly, Agnès, Bodon, Gilles, Blot, Béatrice, Haase, Georg, Goldberg, Yves, Sadoul, Rémy

“…Exosomes are microvesicles released into the extracellular medium upon fusion to the plasma membrane of endosomal intermediates called multivesicular bodies…”
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A Homozygous Ancestral SVA-Insertion-Mediated Deletion in WDR66 Induces Multiple Morphological Abnormalities of the Sperm Flagellum and Male Infertility by Kherraf, Zine-Eddine, Amiri-Yekta, Amir, Dacheux, Denis, Karaouzène, Thomas, Coutton, Charles, Christou-Kent, Marie, Martinez, Guillaume, Landrein, Nicolas, Le Tanno, Pauline, Fourati Ben Mustapha, Selima, Halouani, Lazhar, Marrakchi, Ouafi, Makni, Mounir, Latrous, Habib, Kharouf, Mahmoud, Pernet-Gallay, Karin, Gourabi, Hamid, Robinson, Derrick R., Crouzy, Serge, Blum, Michael, Thierry-Mieg, Nicolas, Touré, Aminata, Zouari, Raoudha, Arnoult, Christophe, Bonhivers, Mélanie, Ray, Pierre F.

“…Multiple morphological abnormalities of the sperm flagellum (MMAF) is a severe form of male infertility defined by the presence of a mosaic of anomalies,…”
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Exosomes as a novel way of interneuronal communication by Chivet, Mathilde, Javalet, Charlotte, Hemming, Fiona, Pernet-Gallay, Karin, Laulagnier, Karine, Fraboulet, Sandrine, Sadoul, Rémy

“…Exosomes are small extracellular vesicles which stem from endosomes fusing with the plasma membrane; they contain lipids, proteins and RNAs that are able to…”
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Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus by Pierre, Virginie, Martinez, Guillaume, Coutton, Charles, Delaroche, Julie, Yassine, Sandra, Novella, Caroline, Pernet-Gallay, Karin, Hennebicq, Sylviane, Ray, Pierre F, Arnoult, Christophe

“…Sperm-head elongation and acrosome formation, which take place during the last stages of spermatogenesis, are essential to produce competent spermatozoa that…”
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Extracellular vesicles from myelodysplastic mesenchymal stromal cells induce DNA damage and mutagenesis of hematopoietic stem cells through miRNA transfer by Meunier, Mathieu, Guttin, Audrey, Ancelet, Sarah, Laurin, David, Zannoni, Johanna, Lefebvre, Christine, Tondeur, Sylvie, Persoons, Virginie, Pezet, Mylène, Pernet-Gallay, Karin, Chuffart, Florent, Rousseaux, Sophie, Testard, Quentin, Thevenon, Julien, Jouzier, Claire, Deleuze, Jean-François, Laulagnier, Karine, Sadoul, Rémy, Chatellard, Christine, Hainaut, Pierre, Polack, Benoît, Cahn, Jean-Yves, Issartel, Jean-Paul, Park, Sophie

“…Physiopathology of myelodysplastic syndrome (MDS) remains poorly understood and the role of the microenvironment is increasingly highlighted. Recent studies in…”
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The Overexpression of GMAP‐210 Blocks Anterograde and Retrograde Transport Between the ER and the Golgi Apparatus by Pernet‐Gallay, Karin, Antony, Claude, Johannes, Ludger, Bornens, Michel, Goud, Bruno, Rios, Rosa M.

“…Golgi Microtubule‐Associated Protein (GMAP)‐210 is a peripheral coiled‐coil protein associated with the cis‐Golgi network that interacts with microtubule minus…”
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Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy by Tadmouri, Abir, Kiyonaka, Shigeki, Barbado, Maud, Rousset, Matthieu, Fablet, Katell, Sawamura, Seishiro, Bahembera, Eloi, Pernet-Gallay, Karin, Arnoult, Christophe, Miki, Takafumi, Sadoul, Karin, Gory-Faure, Sylvie, Lambrecht, Caroline, Lesage, Florian, Akiyama, Satoshi, Khochbin, Saadi, Baulande, Sylvain, Janssens, Veerle, Andrieux, Annie, Dolmetsch, Ricardo, Ronjat, Michel, Mori, Yasuo, De Waard, Michel

“…Calcium current through voltage‐gated calcium channels (VGCC) controls gene expression. Here, we describe a novel signalling pathway in which the VGCC Cacnb4…”
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ALG-2 interacting protein-X (Alix) is essential for clathrin-independent endocytosis and signaling by Mercier, Vincent, Laporte, Marine H., Destaing, Olivier, Blot, Béatrice, Blouin, Cédric M., Pernet-Gallay, Karin, Chatellard, Christine, Saoudi, Yasmina, Albiges-Rizo, Corinne, Lamaze, Christophe, Fraboulet, Sandrine, Petiot, Anne, Sadoul, Rémy

“…The molecular mechanisms and the biological functions of clathrin independent endocytosis (CIE) remain largely elusive. Alix (ALG-2 interacting protein X), has…”
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Microscopic DTI accurately identifies early glioma cell migration: correlation with multimodal imaging in a new glioma stem cell model by Gimenez, Ulysse, Perles-Barbacaru, Adriana-T., Millet, Arnaud, Appaix, Florence, El-Atifi, Michele, Pernet-Gallay, Karin, van der Sanden, Boudewijn, Berger, François, Lahrech, Hana

“…Monitoring glioma cell infiltration in the brain is critical for diagnosis and therapy. Using a new glioma Glio6 mouse model derived from human stem cells we…”
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Functional monitoring of peripheral nerves from electrical impedance measurements by Fouchard, Alexandre, Coizet, Véronique, Sinniger, Valérie, Clarençon, Didier, Pernet-Gallay, Karin, Bonnet, Stéphane, David, Olivier

“…•Electroneurograms and impedance features are recorded in vivo on rodent nerves.•Multi-contact cuff electrodes allow recording compound action…”
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Altered parabrachial nucleus nociceptive processing may underlie central pain in Parkinson’s disease by Pautrat, Arnaud, Al Tannir, Racha, Pernet-Gallay, Karin, Soutrenon, Rémi, Vendramini, Estelle, Sinniger, Valérie, Overton, Paul G., David, Olivier, Coizet, Véronique

“…The presence of central neuropathic pain in Parkinson’s disease suggests that the brain circuits that allow us to process pain could be dysfunctional in the…”
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VE-cadherin Y685F knock-in mouse is sensitive to vascular permeability in recurrent angiogenic organs by Sidibé, Adama, Polena, Helena, Pernet-Gallay, Karin, Razanajatovo, Jeremy, Mannic, Tiphaine, Chaumontel, Nicolas, Bama, Soumalamaya, Maréchal, Irène, Huber, Philippe, Gulino-Debrac, Danielle, Bouillet, Laurence, Vilgrain, Isabelle

“…Covalent modifications such as tyrosine phosphorylation are associated with the breakdown of endothelial cell junctions and increased vascular permeability. We…”
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Intermittent Hypoxia Rewires the Liver Transcriptome and Fires up Fatty Acids Usage for Mitochondrial Respiration by Gaucher, Jonathan, Vial, Guillaume, Montellier, Emilie, Guellerin, Maëlle, Bouyon, Sophie, Lemarie, Emeline, Pelloux, Véronique, Bertrand, Anne, Pernet-Gallay, Karin, Lamarche, Frederic, Borel, Anne-Laure, Arnaud, Claire, Belaidi, Elise, Clément, Karine, Godin Ribuot, Diane, Aron-Wisnewsky, Judith, Pépin, Jean-Louis

“…Sleep Apnea Syndrome (SAS) is one of the most common chronic diseases, affecting nearly one billion people worldwide. The repetitive occurrence of abnormal…”
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Non-microtubular localizations of microtubule-associated protein 6 (MAP6) by Gory-Fauré, Sylvie, Windscheid, Vanessa, Brocard, Jacques, Montessuit, Sylvie, Tsutsumi, Ryouhei, Denarier, Eric, Fukata, Yuko, Bosc, Christophe, Delaroche, Julie, Collomb, Nora, Fukata, Masaki, Martinou, Jean-Claude, Pernet-Gallay, Karin, Andrieux, Annie

“…MAP6 proteins (MAP6s), which include MAP6-N (also called Stable Tubule Only Polypeptide, or STOP) and MAP6d1 (MAP6 domain-containing protein 1, also called…”
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Astrocyte-neuron interplay is critical for Alzheimer's disease pathogenesis and is rescued by TRPA1 channel blockade by Paumier, Adrien, Boisseau, Sylvie, Jacquier-Sarlin, Muriel, Pernet-Gallay, Karin, Buisson, Alain, Albrieux, Mireille

“…The sequence of cellular dysfunctions in preclinical Alzheimer's disease must be understood if we are to plot new therapeutic routes. Hippocampal neuronal…”
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CLIPR-59, a New Trans-Golgi/TGN Cytoplasmic Linker Protein Belonging to the CLIP-170 Family by Perez, Franck, Pernet-Gallay, Karin, Nizak, Clément, Goodson, Holly V., Kreis, Thomas E., Goud, Bruno

“…The microtubule cytoskeleton plays a fundamental role in cell organization and membrane traffic in higher eukaryotes. It is well established that molecular…”
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