Search Results - "Perlmutter, J"

Neurologist care in Parkinson disease: A utilization, outcomes, and survival study by WILLIS, A. W, SCHOOTMAN, M, EVANOFF, B. A, PERLMUTTER, J. S, RACETTE, B. A

“…To investigate the utilization of neurologist providers in the treatment of patients with Parkinson disease (PD) in the United States and determine whether…”
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In vivo amyloid imaging in autopsy-confirmed Parkinson disease with dementia by BURACK, M. A, HARTLEIN, J, FLORES, H. P, TAYLOR-REINWALD, L, PERLMUTTER, J. S, CAIRNS, N. J

“…To investigate the specificity of in vivo amyloid imaging with [(11)C]-Pittsburgh Compound B (PIB) in Parkinson disease dementia (PDD). We performed detailed…”
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Prevalence of parkinsonism and relationship to exposure in a large sample of Alabama welders by RACETTE, B. A, TABBAL, S. D, JENNINGS, D, GOOD, L, PERLMUTTER, J. S, EVANOFF, B

“…To estimate the prevalence of parkinsonism in welders in Alabama and to compare this prevalence with that in a general population sample. The authors screened…”
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Severe acute neurotoxicity reflects absolute intra-carotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine dose in non-human primates by Norris, SA, White, HCB, Tanenbaum, A., Williams, EL, Cruchaga, C., Tian, L., Schmidt, RE, Perlmutter, JS

“…•Absolute MPTP dose differed with acute recovery versus severe acute neurotoxicity.•Body weight and mean brain volume did not differ across outcome…”
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Novel THAP1 sequence variants in primary dystonia by XIAO, J, ZHAO, Y, VAN GERPEN, J. A, SIMON, D. K, TARSY, D, HEDERA, P, TRUONG, D. D, FREI, K. P, DEV BATISH, S, BLITZER, A, PFEIFFER, R. F, GONG, S, BASTIAN, R. W, LEDOUX, M. S, PERLMUTTER, J. S, RACETTE, B. A, TABBAL, S. D, KARIMI, M, PANIELLO, R. C, WSZOLEK, Z. K, UITTI, R. J

“…THAP1 encodes a transcription factor (THAP1) that harbors an atypical zinc finger domain and regulates cell proliferation. An exon 2 insertion/deletion…”
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Stimulation of STN impairs aspects of cognitive control in PD by HERSHEY, T, REVILLA, F. J, WERNLE, A, GIBSON, P. Schneider, DOWLING, J. L, PERLMUTTER, J. S

“…To test the hypothesis that subthalamic nucleus (STN) stimulation in Parkinson disease (PD) patients affects working memory and response inhibition…”
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Practice Parameter:Diagnosis and prognosis of new onset Parkinson disease (an evidence-based review) : Report of the quality standards subcommittee of the american academy of neurology by SUCHOWERSKY, O, REICH, S, PERLMUTTER, J, ZESIEWICZ, T, GRONSETH, G, WEINER, W. J

“…To define key issues in the diagnosis of Parkinson disease (PD), to define features influencing progression, and to make evidence-based recommendations. Two…”
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Dopamine pathway loss in nucleus accumbens and ventral tegmental area predicts apathetic behavior in MPTP-lesioned monkeys by Brown, C.A., Campbell, M.C., Karimi, M., Tabbal, S.D., Loftin, S.K., Tian, L.L., Moerlein, S.M., Perlmutter, J.S.

“…Apathy, primarily defined as a lack of motivation, commonly occurs in people with Parkinson disease (PD). Although dysfunction of basal ganglia pathways may…”
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Predicted sensitivity to endocrine therapy for stage II-III hormone receptor-positive and HER2-negative (HR+/HER2−) breast cancer before chemo-endocrine therapy by Du, L., Yau, C., Brown-Swigart, L., Gould, R., Krings, G., Hirst, G.L., Bedrosian, I., Layman, R.M., Carter, J.M., Klein, M., Venters, S., Shad, S., van der Noordaa, M., Chien, A.J., Haddad, T., Isaacs, C., Pusztai, L., Albain, K., Nanda, R., Tripathy, D., Liu, M.C., Boughey, J., Schwab, R., Hylton, N., DeMichele, A., Perlmutter, J., Yee, D., Berry, D., van't Veer, L., Valero, V., Esserman, L.J., Symmans, W.F.

“…We proposed that a test for sensitivity to the adjuvant endocrine therapy component of treatment for patients with stage II-III breast cancer (SET2,3) should…”
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Reduced uptake of [18 F]FDOPA PET in asymptomatic welders with occupational manganese exposure by CRISWELL, S. R, PERLMUTTER, J. S, VIDEEN, T. O, MOERLEIN, S. M, FLORES, H. P, BIRKE, A. M, RACETTE, B. A

“…Welding exposes workers to manganese (Mn) fumes, but it is unclear if this exposure damages dopaminergic neurons in the basal ganglia and predisposes…”
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Treatment Efficacy Score—continuous residual cancer burden-based metric to compare neoadjuvant chemotherapy efficacy between randomized trial arms in breast cancer trials by Marczyk, M., Mrukwa, A., Yau, C., Wolf, D., Chen, Y.-Y., Balassanian, R., Nanda, R., Parker, B.A., Krings, G., Sattar, H., Zeck, J.C., Albain, K.S., Boughey, J.C., Liu, M.C., Elias, A.D., Clark, A.S., Venters, S.J., Shad, S., Basu, A., Asare, S.M., Buxton, M., Asare, A.L., Rugo, H.S., Perlmutter, J., DeMichele, A.M., Yee, D., Berry, D.A., Veer, L. van’t, Symmans, W.F., Esserman, L., Pusztai, L.

“…Difference in pathologic complete response (pCR) rate after neoadjuvant chemotherapy does not capture the impact of treatment on downstaging of residual cancer…”
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Practice Parameter:Neuroprotective strategies and alternative therapies for Parkinson disease (an evidence-based review) : Report of the quality standards subcommittee of the american academy of neurology by SUCHOWERSKY, O, GRONSETH, G, PERLMUTTER, J, REICH, S, ZESIEWICZ, T, WEINER, W. J

“…To define key issues in the management of Parkinson disease (PD) relating to neuroprotective strategies and alternative treatments, and to make evidence-based…”
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Effects of deep brain stimulation of dorsal versus ventral subthalamic nucleus regions on gait and balance in Parkinson's disease by McNeely, M E, Hershey, T, Campbell, M C, Tabbal, S D, Karimi, M, Hartlein, J M, Lugar, H M, Revilla, F J, Perlmutter, J S, Earhart, G M

“…ObjectiveDeep brain stimulation (DBS) of the subthalamic nucleus (STN) improves motor function, including gait and stability, in people with Parkinson's…”
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Welding-related parkinsonism: Clinical features, treatment, and pathophysiology by RACETTE, B. A, MCGEE-MINNICH, L, MOERLEIN, S. M, MINK, J. W, VIDEEN, T. O, PERLMUTTER, J. S

“…To determine whether welding-related parkinsonism differs from idiopathic PD. Welding is considered a cause of parkinsonism, but little information is…”
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Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood by Perlmutter, Susan J, Leitman, Susan F, Garvey, Marjorie A, Hamburger, Susan, Feldman, Elad, Leonard, Henrietta L, Swedo, Susan E

“…In children, exacerbations of tics and obsessive symptoms may occur after infection with group A β-haemolytic streptococci. If post-streptococcal autoimmunity…”
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Regulation of dopamine D3 receptor in the striatal regions and substantia nigra in diffuse Lewy body disease by Sun, J, Cairns, N.J, Perlmutter, J.S, Mach, R.H, Xu, J

“…Highlights • Quantitative autoradiography of dopamine D1 , D2 , D3 receptors, VMAT2 and DAT. • Dopamine D2 and D3 receptor densities were measured using a…”
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Subthalamic nucleus stimulation-induced regional blood flow responses correlate with improvement of motor signs in Parkinson disease by Karimi, M., Golchin, N., Tabbal, S. D., Hershey, T., Videen, T. O., Wu, J., Usche, J. W. M., Revilla, F. J., Hartlein, J. M., Wernle, A. R., Mink, J. W., Perlmutter, J. S.

“…Deep brain stimulation of the subthalamic nucleus (STN DBS) improves motor symptoms in idiopathic Parkinson's disease, yet the mechanism of action remains…”
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HDQLIFE: development and assessment of health-related quality of life in Huntington disease (HD) by Carlozzi, N. E., Schilling, S. G., Lai, J.-S., Paulsen, J. S., Hahn, E. A., Perlmutter, J. S., Ross, C. A., Downing, N. R., Kratz, A. L., McCormack, M. K., Nance, M. A., Quaid, K. A., Stout, J. C., Gershon, R. C., Ready, R. E., Miner, J. A., Barton, S. K., Perlman, S. L., Rao, S. M., Frank, S., Shoulson, I., Marin, H., Geschwind, M. D., Dayalu, P., Goodnight, S. M., Cella, D.

“…Purpose Huntington disease (HD) is a chronic, debilitating genetic disease that affects physical, emotional, cognitive, and social health. Existing…”
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Cerebral blood flow responses to dorsal and ventral STN DBS correlate with gait and balance responses in Parkinson's disease by Hill, K.K., Campbell, M.C., McNeely, M.E., Karimi, M., Ushe, M., Tabbal, S.D., Hershey, T., Flores, H.P., Hartlein, J.M., Lugar, H.M., Revilla, F.J., Videen, T.O., Earhart, G.M., Perlmutter, J.S.

“…The effects of subthalamic nucleus (STN) deep brain stimulation (DBS) on gait and balance vary and the underlying mechanisms remain unclear. DBS location may…”
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Pathologic correlates of supranuclear gaze palsy with parkinsonism by Martin, W.R.W, Hartlein, J, Racette, B.A, Cairns, N, Perlmutter, J.S

“…Abstract Introduction Supranuclear gaze palsy (SGP) is a classic clinical feature of progressive supranuclear palsy (PSP) but is not specific for this…”
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