Search Results - "Perkins, S A"
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Cognitive control in social situations: A role for the dorsolateral prefrontal cortex
Published in NeuroImage (Orlando, Fla.) (01-04-2008)“…Using functional magnetic resonance imaging (fMRI), we investigated brain activity elicited by a computer-animated child's actions that appeared consistent and…”
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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
Published in Genes & development (01-05-1994)“…The neurofibromatosis (NF1) gene shows significant homology to mammalian GAP and is an important regulator of the ras signal transduction pathway. To study the…”
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Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
Published in Cell (08-10-1993)“…Newborn mice homozygous for a targeted disruption of insulin-like growth factor gene (Igf-1) exhibit a growth deficiency similar in severity to that previously…”
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4
Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4
Published in Oncogene (14-09-2006)“…The four members of the ErbB family of receptor tyrosine kinases are involved in development and tumorigenesis of the mammary gland. Whereas the epidermal…”
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Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop
Published in Genes & development (01-12-1992)“…myc genes are thought to function in the processes of cellular proliferation and differentiation. To gain insight into the role of the N-myc gene during…”
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Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
Published in Oncogene (11-05-2017)“…Inhibitors of the mechanistic target of rapamycin (mTOR) are currently used to treat advanced metastatic breast cancer. However, whether an aggressive…”
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neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice
Published in Molecular and Cellular Biology (01-06-1997)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Laser in situ keratomileusis for myopia and astigmatism: 6 month results
Published in Journal of cataract and refractive surgery (01-06-1998)“…To evaluate the visual and refractive results of laser in situ keratomileusis (LASIK) for mild to moderate myopia with or without astigmatism. Barnet-Dulaney…”
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9
F-mulv acceleration of myelomonocytic tumorigenesis in SV40 large T antigen transgenic mice is accompanied by retroviral insertion at Fli1 and a novel locus, Fim4
Published in Leukemia (01-09-2002)“…We describe here the development of a murine system for the identification of genes involved in myelomonocytic neoplasms. Transgenic C57BL/6J mice expressing…”
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Pathogenesis of Placental Site Trophoblastic Tumor May Require the Presence of a Paternally Derived X Chromosome
Published in Laboratory investigation (01-06-2000)“…Placental site trophoblastic tumor (PSTT) is a neoplastic proliferation of intermediate trophoblasts that invades the myometrium at the placental site after a…”
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Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein
Published in Molecular and Cellular Biology (01-05-1991)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Targeting of Transgene Expression to Monocyte/Macrophages by the gp91-Phox Promoter and Consequent Histiocytic Malignancies
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1991)“…A component of a heterodimeric cytochrome b, designated gp91-phox, is required for the microbicidal activity of phagocytic cells and is expressed exclusively…”
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Molecular analysis of Evi1, a zinc finger oncogene involved in myeloid leukemia
Published in Current topics in microbiology and immunology (1996)“…Through chromosomal rearrangements and/or proviral insertions, a number of genes encoding nuclear transcription factors have been identified that play key…”
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Patterns of Evi-1 expression in embryonic and adult tissues suggest that Evi-1 plays an important regulatory role in mouse development
Published in Development (Cambridge) (01-02-1991)“…Evi-1 is a putative protooncogene first identified as a common site of retroviral integration in murine myeloid leukemias. It encodes a 145 Ã 10(3) Mr nuclear…”
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Vaccination with a Recombinant Vesicular Stomatitis Virus Expressing an Influenza Virus Hemagglutinin Provides Complete Protection from Influenza Virus Challenge
Published in Journal of Virology (01-06-1998)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification of candidate target genes for EVI-1, a zinc finger oncoprotein, using a novel selection strategy
Published in Oncogene (24-09-1998)“…We have sought to identify and isolate target genes for the zinc finger protein, EVI-1, which has been implicated in the genesis of myelogenous leukemia both…”
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Assessment of F-MuLV-induced tumorigenesis reveals new candidate tumor genes including Pecam1, St7, and Prim2
Published in Leukemia (01-01-2006)Get full text
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Gene expression profiling of ErbB receptor and ligand-dependent transcription
Published in Oncogene (19-02-2004)“…Overexpression of ErbB2 and ErbB4 receptors in breast cancers may be accompanied by contrasting clinical outcomes. To investigate the molecular mechanisms…”
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Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies
Published in Nucleic acids research (01-07-2012)“…Numerous examples exist of how disrupting the actions of physiological regulators of blood cell development yields hematologic malignancies. The master…”
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The pathology of murine myelogenous leukemias
Published in Current topics in microbiology and immunology (1989)“…Murine myelogenous leukemias can be classified into several distinct subgroups based on morphology, cytochemical staining, and immunoreactivity. The leukemias…”
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