Search Results - "Perkins, Gemma M."

Structure–activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1′ side chain by Davies, Stephen J., Ayscough, Andrew P., Beckett, R.Paul, Bragg, Ryan A., Clements, John M., Doel, Sheila, Grew, Christine, Launchbury, Steven B., Perkins, Gemma M., Pratt, Lisa M., Smith, Helen K., Spavold, Zoë M., Thomas, S.Wayne, Todd, Richard S., Whittaker, Mark

“…Structural modifications to the peptide deformylase inhibitor BB-3497 are described. In this paper, we describe the initial SAR around this lead for…”
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Identification of Novel Ligands for the Gabapentin Binding Site on the α2δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents by Bryans, Justin S, Davies, Natasha, Gee, Nicolas S, Dissanayake, Visaka U. K, Ratcliffe, Giles S, Horwell, David C, Kneen, Clare O, Morrell, Andrew I, Oles, Ryszard J, O'Toole, John C, Perkins, Gemma M, Singh, Lakhbir, Suman-Chauhan, Nirmala, O'Neill, Jacqueline A

“…As part of a program to investigate the structure−activity relationships of Gabapentin (Neurontin), a number of alkylated analogues were synthesized and…”
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Identification of Novel Ligands for the Gabapentin Binding Site on the α 2 δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents by Bryans, Justin S., Davies, Natasha, Gee, Nicolas S., Dissanayake, Visaka U. K., Ratcliffe, Giles S., Horwell, David C., Kneen, Clare O., Morrell, Andrew I., Oles, Ryszard J., O'Toole, John C., Perkins, Gemma M., Singh, Lakhbir, Suman-Chauhan, Nirmala, O'Neill, Jacqueline A.

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