Search Results - "Perkins, Amy E"

Prenatal alcohol exposure alters expression of genes involved in cell adhesion, immune response, and toxin metabolism in adolescent rat hippocampus by Khalifa, Amal, Palu, Rebecca, Perkins, Amy E, Volz, Avery

“…Prenatal alcohol exposure (PAE) can result in mild to severe consequences for children throughout their lives, with this range of symptoms referred to as Fetal…”
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Stereological Analysis of Microglia in Aged Male and Female Fischer 344 Rats in Socially Relevant Brain Regions by Perkins, Amy E., Piazza, Michelle K., Deak, Terrence

“…•The MEA and BNST displayed greater microglial density than other sites examined.•Late aging was associated with greater numbers of microglia in MEA in males…”
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Late aging–associated increases in L-DOPA–induced dyskinesia are accompanied by heightened neuroinflammation in the hemi-parkinsonian rat by Lanza, Kathryn, Perkins, Amy E., Deak, Terrence, Bishop, Christopher

“…Aging is a primary risk factor for the development of Parkinson's disease (PD), and aging differentially predicts the incidence of L-DOPA–induced dyskinesia…”
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Analysis of c-Fos induction in response to social interaction in male and female Fisher 344 rats by Perkins, Amy E., Woodruff, Elizabeth R., Chun, Lauren E., Spencer, Robert L., Varlinskaya, Elena, Deak, Terrence

“…•Adult females exhibited greater levels of social behavior relative to adult males.•C-Fos induction was similar in context- and social-interaction exposed…”
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PennPET Explorer: Design and Preliminary Performance of a Whole-Body Imager by Karp, Joel S., Viswanath, Varsha, Geagan, Michael J., Muehllehner, Gerd, Pantel, Austin R., Parma, Michael J., Perkins, Amy E., Schmall, Jeffrey P., Werner, Matthew E., Daube-Witherspoon, Margaret E.

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Uncovering New Metabolic Capabilities of Bacillus subtilis Using Phenotype Profiling of Rifampin-Resistant rpoB Mutants by PERKINS, Amy E, NICHOLSON, Wayne L

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Fibrillization of 40-Residue β-Amyloid Peptides in Membrane-Like Environments Leads to Different Fibril Structures and Reduced Molecular Polymorphisms by Cheng, Qinghui, Hu, Zhi-Wen, Tobin-Miyaji, Yuto, Perkins, Amy E, Deak, Terrence, Qiang, Wei

“…The molecular-level polymorphism in β-Amyloid (Aβ) fibrils have recently been considered as a pathologically relevant factor in Alzheimer's disease (AD)…”
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Age-related decline in social interaction is associated with decreased c-Fos induction in select brain regions independent of oxytocin receptor expression profiles by Ravenel, J. Russell, Perkins, Amy E., Tomczik, Angela, Defendini, Ana, Strnad, Helen K., Varlinskaya, Elena, Deak, Terrence, Spencer, Robert L.

“…•Social interactions selectively increased c-Fos mRNA in distinct brain regions in young, but not aged female rats.•Age-related differences in c-Fos mRNA…”
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A working model for the assessment of disruptions in social behavior among aged rats: The role of sex differences, social recognition, and sensorimotor processes by Perkins, Amy E., Doremus-Fitzwater, Tamara L., Spencer, Robert L., Varlinskaya, Elena I., Conti, Melissa M., Bishop, Christopher, Deak, Terrence

“…Aging results in a natural decline in social behavior, yet little is known about the processes underlying these changes. Engaging in positive social…”
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Prenatal Alcohol Exposure Disrupts Performance in a Differential Reinforcement of Low Rates Task Specifically in Adolescent Male Rats by Perkins, Amy E, Dart, Ellie, Kaiser, Daren

“…Prenatal alcohol exposure (PAE) can lead to a wide range of adverse effects in humans, including impaired self-control and increased impulsive behavior…”
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PennPET Explorer: Design and Preliminary Performance of a Whole-Body Imager by Karp, Joel S, Viswanath, Varsha, Geagan, Michael J, Muehllehner, Gerd, Pantel, Austin R, Parma, Michael J, Perkins, Amy E, Schmall, Jeffrey P, Werner, Matthew E, Daube-Witherspoon, Margaret E

“…We report on the development of the PennPET Explorer whole-body imager. The PennPET Explorer is a multiring system designed with a long axial field of view…”
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Performance of Philips Gemini TF PET/CT Scanner with Special Consideration for Its Time-of-Flight Imaging Capabilities by Surti, Suleman, Kuhn, Austin, Werner, Matthew E, Perkins, Amy E, Kolthammer, Jeffrey, Karp, Joel S

“…Results from a new PET/CT scanner using lutetium-yttrium oxyorthosilicate (LYSO) crystals for the PET component are presented. This scanner, which operates in…”
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Late aging alters behavioral sensitivity to ethanol in a sex-specific manner in Fischer 344 rats by Perkins, Amy E., Vore, Andrew S., Lovelock, Dennis, Varlinskaya, Elena, Deak, Terrence

“…Responsiveness to ethanol (EtOH) differs as a function of age. Adolescent rodents are less sensitive than adults to the sedative effects of EtOH, whereas they…”
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Impact of housing conditions on social behavior, neuroimmune markers, and oxytocin receptor expression in aged male and female Fischer 344 rats by Perkins, Amy E., Varlinskaya, Elena I., Deak, Terrence

“…Aging is associated with a substantial decline in social behavior, whereas positive social interaction can improve overall health in aged individuals. In…”
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From adolescence to late aging: A comprehensive review of social behavior, alcohol, and neuroinflammation across the lifespan by Perkins, Amy E, Varlinskaya, Elena I, Deak, Terrence

“…The passage of time dictates the pace at which humans and other organisms age but falls short of providing a complete portrait of how environmental, lifestyle…”
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Investigation of optimization-based reconstruction with an image-total-variation constraint in PET by Zhang, Zheng, Ye, Jinghan, Chen, Buxin, Perkins, Amy E, Rose, Sean, Sidky, Emil Y, Kao, Chien-Min, Xia, Dan, Tung, Chi-Hua, Pan, Xiaochuan

“…Interest remains in reconstruction-algorithm research and development for possible improvement of image quality in current PET imaging and for enabling…”
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Patient-derived PixelPrint phantoms for evaluating clinical imaging performance of a deep learning CT reconstruction algorithm by Im, Jessica Y, Halliburton, Sandra S, Mei, Kai, Perkins, Amy E, Wong, Eddy, Roshkovan, Leonid, Sandvold, Olivia F, Liu, Leening P, Gang, Grace J, Noël, Peter B

“… Deep learning reconstruction (DLR) algorithms exhibit object-dependent resolution and noise performance. Thus, traditional geometric CT phantoms cannot fully…”
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Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors by Perkins, Amy E., Piazza, Michelle K., Vore, Andrew S., Deak, Molly M., Varlinskaya, Elena I., Deak, Terrence

“…•Aged males did not exhibit increased basal inflammation in hippocampal tissue.•Extracellular release of cytokines and chemokines did not vary by age.•Release…”
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Reproducible spectral CT thermometry with liver-mimicking phantoms for image-guided thermal ablation by Liu, Leening P, Pua, Rizza, Rosario-Berrios, Derick N, Sandvold, Olivia F, Perkins, Amy E, Cormode, David P, Shapira, Nadav, Soulen, Michael C, Noël, Peter B

“… Evaluate the reproducibility, temperature tolerance, and radiation dose requirements of spectral CT thermometry in tissue-mimicking phantoms to establish its…”
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Determination of accuracy and precision of lesion uptake measurements in human subjects with time-of-flight PET by Daube-Witherspoon, Margaret E, Surti, Suleman, Perkins, Amy E, Karp, Joel S

“…Inclusion of time-of-flight (TOF) information in PET reconstructions has been demonstrated to improve image quality through better signal-to-noise ratios,…”
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