Search Results - "Perkin, Michael R"
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Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants
Published in The New England journal of medicine (05-05-2016)“…Six foods commonly associated with food allergy were introduced in the diets of children at 3 months or 6 months of age. Intention-to-treat analysis showed no…”
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Timing of Allergenic Food Introduction and Risk of Immunoglobulin E-Mediated Food Allergy: A Systematic Review and Meta-analysis
Published in JAMA pediatrics (01-05-2023)“…Earlier egg and peanut introduction probably reduces risk of egg and peanut allergy, respectively, but it is uncertain whether food allergy as a whole can be…”
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Enquiring About Tolerance (EAT) study: Feasibility of an early allergenic food introduction regimen
Published in Journal of allergy and clinical immunology (01-05-2016)“…Background The influence of early exposure to allergenic foods on the subsequent development of food allergy remains uncertain. Objective We sought to…”
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Early introduction of peanut reduces peanut allergy across risk groups in pooled and causal inference analyses
Published in Allergy (Copenhagen) (01-05-2023)“…Background The Learning Early About Peanut allergy (LEAP) study has shown the effectiveness of early peanut introduction in prevention of peanut allergy (PA)…”
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Efficacy of the Enquiring About Tolerance (EAT) study among infants at high risk of developing food allergy
Published in Journal of allergy and clinical immunology (01-12-2019)“…The Enquiring About Tolerance (EAT) study was a randomized trial of the early introduction of allergenic solids into the infant diet from 3 months of age. The…”
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Development of an intervention for reducing infant bathing frequency
Published in PloS one (29-02-2024)“…Bathing babies less frequently and intensively in the first six months of life may prevent eczema, but this has not yet been definitively tested in a…”
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The hygiene hypothesis for allergy - conception and evolution
Published in Frontiers in allergy (24-11-2022)“…In 1989, a short paper entitled "Hay fever, hygiene and household size" observed that British children from larger families were less likely to develop hay…”
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Gut microbiota and development of atopic eczema in 3 European birth cohorts
Published in Journal of allergy and clinical immunology (01-08-2007)“…Background Stimulation of the immune system by gut microbes might prevent allergy development. Objective The present study examined the hypothesis that…”
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Association between domestic water hardness, chlorine, and atopic dermatitis risk in early life: A population-based cross-sectional study
Published in Journal of allergy and clinical immunology (01-08-2016)“…Background Domestic water hardness and chlorine have been suggested as important risk factors for atopic dermatitis (AD). Objective We sought to examine the…”
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RCT evidence suggests that solids introduction before age 6 months does not adversely impact duration of breastfeeding
Published in Maternal and child nutrition (01-10-2020)Get full text
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Reduced diversity in the early fecal microbiota of infants with atopic eczema
Published in Journal of allergy and clinical immunology (2008)“…Background It might be that early intestinal colonization by bacteria in westernized infants fails to give rise to sufficient immune stimulation to support…”
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Food Proteins in Human Breast Milk and Probability of IgE-Mediated Allergic Reaction in Children During Breastfeeding: A Systematic Review
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-05-2022)“…Previous reports suggested that food proteins present in human milk (HM) may trigger symptoms in allergic children during breastfeeding, but existing evidence…”
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Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT
Published in Health technology assessment (Winchester, England) (01-07-2024)“…Atopic eczema is a common childhood skin problem linked with asthma, food allergy and allergic rhinitis that impairs quality of life. To determine whether…”
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Regular breakfast consumption and type 2 diabetes risk markers in 9- to 10-year-old children in the child heart and health study in England (CHASE): a cross-sectional analysis
Published in PLoS medicine (01-09-2014)“…Regular breakfast consumption may protect against type 2 diabetes risk in adults but little is known about its influence on type 2 diabetes risk markers in…”
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Early introduction of allergenic food for all infants
Published in The Lancet (British edition) (25-06-2022)“…In the Enquiring About Tolerance (EAT) study, six allergenic foods were introduced from 3 months of age and by age 3 years, a 20% reduction in food allergy to…”
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Inter-Relationship between Rhinitis and Conjunctivitis in Allergic Rhinoconjunctivitis and Associated Risk Factors in Rural UK Children
Published in PloS one (24-11-2015)“…Allergic conjunctivitis (AC) is a common condition, especially in childhood. The extent to which it occurs concurrently with or independently from allergic…”
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Palforzia for peanut allergy: Panacea or predicament
Published in Clinical and experimental allergy (01-06-2022)Get full text
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Perception of severity of adverse events in oral immunotherapy
Published in The Lancet (British edition) (08-02-2020)Get full text
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Oral Desensitization to Peanuts
Published in The New England journal of medicine (22-11-2018)“…Once a peanut allergy develops, advice has historically been simple: lifelong complete avoidance is needed to prevent systemic allergic reactions, some of…”
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Double-blind food challenges can be conducted effectively by using interspersed active and placebo doses among children
Published in Journal of allergy and clinical immunology (01-08-2013)“…Studies using both 2-day double-blind protocols and interspersed single-day schedules report that the large majority of participants experiencing IgE-mediated…”
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