Search Results - "Perk, Jonathan"
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Id family of helix-loop-helix proteins in cancer
Published in Nature reviews. Cancer (01-08-2005)“…Over the past few decades, biologists have identified key molecular signatures associated with a wide range of human cancers. Recently, animal models have been…”
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ID genes mediate tumor reinitiation during breast cancer lung metastasis
Published in Proceedings of the National Academy of Sciences - PNAS (04-12-2007)“…The establishment of distant metastases depends on the capacity of small numbers of cancer cells to regenerate a tumor after entering a target tissue. The…”
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Protein-binding elements establish in the oocyte the primary imprint of the Prader-Willi/Angelman syndromes domain
Published in Proceedings of the National Academy of Sciences - PNAS (23-06-2009)“…Imprinting of the PWS/AS 2.4 Mb domain in the human is controlled by a paternally active imprinting center (PWS-IC). PWS-IC on the maternal allele is…”
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Reassessment of Id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-Id1 antibody
Published in Cancer research (Chicago, Ill.) (15-11-2006)“…Id proteins are a class of dominant-negative antagonists of helix-loop-helix transcription factors and have been shown to control differentiation of a variety…”
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Autosomal Dominant Trigeminal Neuralgia (P7-12.003)
Published in Neurology (25-04-2023)“…Abstract only…”
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The imprinting box of the Prader-Willi/Angelman syndrome domain
Published in Nature genetics (01-12-2000)“…A subset of mammalian genes is monoallelically expressed in a parent-of-origin manner. These genes are subject to an imprinting process that epigenetically…”
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COVID‐19–associated myositis with severe proximal and bulbar weakness
Published in Muscle & nerve (01-09-2020)Get full text
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Published in Muscle & nerve (01-01-2021)“…See article on pages E9–E10 in this issue …”
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Published in Muscle & nerve (01-01-2021)“…See article on pages E9–E10 in this issue…”
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Quality Improvement of Quality Improvement (P13-2.005)
Published in Neurology (25-04-2023)“…Abstract only…”
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COVID-19 associated myositis with severe proximal and bulbar weakness (P9-9.006)
Published in Neurology (03-05-2022)“…Abstract only…”
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Jamaican Susumber Berry Poisoning Mimicking Acute Stroke
Published in Cerebrovascular diseases (Basel, Switzerland) (2023)“…Stroke mimics are non-vascular conditions that present with acute focal neurological deficits, simulating an acute ischemic stroke. Susumber berry (SB)…”
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Skeletal Muscle Manifestations and Creatine Kinase in COVID-19
Published in Neurohospitalist (01-10-2022)“…Background and Purpose Skeletal muscle symptoms and elevated creatine kinase (CK) levels have been consistently reported as part of the COVID-19 disease…”
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Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo
Published in Nature biotechnology (01-01-2008)“…Transcription factors are important targets for the treatment of a variety of malignancies but are extremely difficult to inhibit, as they are located in the…”
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The imprinting mechanism of the Prader-Willi/Angelman regional control center
Published in The EMBO journal (01-11-2002)“…The 2 Mb domain on chromosome 15q11–q13 that carries the imprinted genes involved in Prader–Willi (PWS) and Angelman (AS) syndromes is under the control of an…”
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Erratum: Id family of helix-loop-helix proteins in cancer
Published in Nature reviews. Cancer (01-09-2005)Get full text
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The imprinting box of the mouse Igf2r gene
Published in Nature (London) (07-01-1999)“…Genomic imprinting is a phenomenon characterized by parent-of-origin-specific expression. The imprint is a mark established during germ-cell development to…”
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