Search Results - "Periyasamy, Sankaridrug M"

Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin by Tian, Jiang, Shidyak, Amjad, Periyasamy, Sankaridrug M, Haller, Steven, Taleb, Mohamed, El-Okdi, Nasser, Elkareh, Jihad, Gupta, Shalini, Gohara, Sabry, Fedorova, Olga V, Cooper, Christopher J, Xie, Zijian, Malhotra, Deepak, Bagrov, Alexei Y, Shapiro, Joseph I

“…Spironolactone has been noted to attenuate cardiac fibrosis. We have observed that the cardiotonic steroid marinobufagenin plays an important role in the…”
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Marinobufagenin Stimulates Fibroblast Collagen Production and Causes Fibrosis in Experimental Uremic Cardiomyopathy by Elkareh, Jihad, Kennedy, David J, Yashaswi, Belvadi, Vetteth, Sandeep, Shidyak, Amjad, Kim, Eric G.R, Smaili, Sleiman, Periyasamy, Sankaridrug M, Hariri, Imad M, Fedorova, Larisa, Liu, Jiang, Wu, Liang, Kahaleh, M Bashar, Xie, Zijian, Malhotra, Deepak, Fedorova, Olga V, Kashkin, Vladimir A, Bagrov, Alexei Y, Shapiro, Joseph I

“…We have observed recently that experimental renal failure in the rat is accompanied by increases in circulating concentrations of the cardiotonic steroid,…”
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Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy by Elkareh, Jihad, Periyasamy, Sankaridrug M, Shidyak, Amjad, Vetteth, Sandeep, Schroeder, Jeremy, Raju, Vanamala, Hariri, Imad M, El-Okdi, Nasser, Gupta, Shalini, Fedorova, Larisa, Liu, Jiang, Fedorova, Olga V, Kahaleh, M Bashar, Xie, Zijian, Malhotra, Deepak, Watson, Dennis K, Bagrov, Alexei Y, Shapiro, Joseph I

“…The cardiotonic steroid marinobufagenin (MBG) has been implicated in the pathogenesis of experimental uremic cardiomyopathy, which is characterized by…”
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Partial nephrectomy as a model for uremic cardiomyopathy in the mouse by Kennedy, David J, Elkareh, Jihad, Shidyak, Amjad, Shapiro, Anna P, Smaili, Sleiman, Mutgi, Krishna, Gupta, Shalini, Tian, Jiang, Morgan, Eric, Khouri, Samer, Cooper, Christopher J, Periyasamy, Sankaridrug M, Xie, Zijian, Malhotra, Deepak, Fedorova, Olga V, Bagrov, Alexei Y, Shapiro, Joseph I

“…Because of the plethora of genetic manipulations available in the mouse, we performed a partial nephrectomy in the mouse and examined whether the phenotypical…”
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Central Role for the Cardiotonic Steroid Marinobufagenin in the Pathogenesis of Experimental Uremic Cardiomyopathy by Kennedy, David J, Vetteth, Sandeep, Periyasamy, Sankaridrug M, Kanj, Mohamed, Fedorova, Larisa, Khouri, Samer, Kahaleh, M Bashar, Xie, Zijian, Malhotra, Deepak, Kolodkin, Nikolai I, Lakatta, Edward G, Fedorova, Olga V, Bagrov, Alexei Y, Shapiro, Joseph I

“…Patients with chronic renal failure develop a “uremic” cardiomyopathy characterized by diastolic dysfunction, cardiac hypertrophy, and systemic oxidant stress…”
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Ouabain induces endocytosis of plasmalemmal Na/K-ATPase in LLC-PK1 cells by a clathrin-dependent mechanism by Liu, Jiang, Kesiry, Riad, Periyasamy, Sankaridrug M., Malhotra, Deepak, Xie, Zijian, Shapiro, Joseph I.

“…Ouabain induces endocytosis of plasmalemmal Na/K-ATPase in LLC-PK1 cells by a clathrin-dependent mechanism. We have demonstrated that ouabain causes dose- and…”
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Salt loading induces redistribution of the plasmalemmal Na/K-ATPase in proximal tubule cells by Periyasamy, Sankaridrug M., Liu, Jiang, Tanta, Feras, Kabak, Besher, Wakefield, Brent, Malhotra, Deepak, Kennedy, David J., Nadoor, Alaa, Fedorova, Olga V., Gunning, William, Xie, Zijian, Bagrov, Alexei Y., Shapiro, Joseph I.

“…Salt loading induces redistribution of the plasmalemmal Na/K-ATPase in proximal tubule cells. We have reported that digitalis-like substances (cardiotonic…”
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Effect of chronic renal failure on cardiac contractile function, calcium cycling, and gene expression of proteins important for calcium homeostasis in the rat by KENNEDY, David, OMRAN, Eiad, PERIYASAMY, Sankaridrug M, NADOOR, Jalaa, PRIYADARSHI, Anumeet, WILLEY, James C, MALHOTRA, Deepak, ZIJIAN XIE, SHAPIRO, Joseph I

“…Patients with chronic renal failure frequently develop cardiac hypertrophy and diastolic dysfunction; however, the mechanisms by which this occurs are still…”
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Ouabain decreases sarco(endo)plasmic reticulum calcium ATPase activity in rat hearts by a process involving protein oxidation by Kennedy, David J, Vetteth, Sandeep, Xie, Miaorong, Periyasamy, Sankaridrug M, Xie, Zijian, Han, Chi, Basrur, Venkatesha, Mutgi, Krishna, Fedorov, Vladimir, Malhotra, Deepak, Shapiro, Joseph I

“…The effect of cardiac glycosides to increase cardiac inotropy by altering Ca(2+) cycling is well known but still poorly understood. The studies described in…”
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Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells by Liu, Jiang, Periyasamy, Sankaridrug M., Gunning, William, Fedorova, Olga V., Bagrov, Alexei Y., Malhotra, Deepak, Xie, Zijian, Shapiro, Joseph I.

“…Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells. The decreases in proximal tubule sodium reabsorption seen with…”
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Effect of green tea extract on cardiac hypertrophy following 5/6 nephrectomy in the rat by Priyadarshi, Snigdha, Valentine, Brandon, Han, Chi, Fedorova, Olga V., Bagrov, Alexei Y., Liu, Jiang, Periyasamy, Sankaridrug M., Kennedy, David, Malhotra, Deepak, Xie, Zijian, Shapiro, Joseph I.

“…Effect of green tea extract on cardiac hypertrophy following 5/6 nephrectomy in the rat. Left ventricular hypertrophy commonly complicates chronic renal…”
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Effects of uremic serum on isolated cardiac myocyte calcium cycling and contractile function by Periyasamy, Sankaridrug M., Chen, Jie, Cooney, Derek, Carter, Patricia, Omran, Eiad, Tian, Jiang, Priyadarshi, Snigdha, Bagrov, Alexei, Fedorova, Olga, Malhotra, Deepak, Xie, Zijian, Shapiro, Joseph I.

“…Effects of uremic serum on isolated cardiac myocyte calcium cycling and contractile function. Diastolic dysfunction occurs in patients with chronic renal…”
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Effects of hypokalemia on cardiac growth by Xie, Z, Liu, J, Malhotra, D, Sheridan, T, Periyasamy, S M, Shapiro, J I

“…In neonatal myocytes grown in culture, reductions in extracellular potassium concentration produced a hypertrophic response as assessed by induction of early…”
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Functional Coupling of Phosphorylation and Nucleotide Binding Sites in the Proteolytic Fragments of Na/K-ATPase by Zolotarjova, N, Periyasamy, S M, Huang, W H, Askari, A

“…Cleavage of the α-subunit of Na /K -ATPase by trypsin at Arg -Ala causes enzyme inhibition which has been suggested to be due to altered alignment of…”
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Central role for the cardiotonic steroid marinobufagenin in the pathogenesis of experimental uremic cardiomyopathy. Commentary by MANUNTA, Paolo, FERRANDI, Mara, MALHOTRA, Deepak, KOLODKIN, Nikolai I, LAKATTA, Edward G, FEDOROVA, Olga V, BAGROV, Alexei Y, SHAPIRO, Joseph I, KENNEDY, David J, VETTETH, Sandeep, PERIYASAMY, Sankaridrug M, KANJ, Mohamed, FEDOROVA, Larisa, KHOURI, Samer, KAHALEH, M. Bashar, ZIJIAN XIE

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Similarities and Differences between the Properties of Native and Recombinant Na+/K+-ATPases by Xie, ZiJian, Wang, Yahong, Liu, Guoquan, Zolotarjova, Nina, Periyasamy, Sankaridrug M., Askari, Amir

“…Progress of mutagenesis studies on the relation of the structure of Na+/K+-ATPase to its reaction mechanism has been impeded by the paucity of information on…”
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Reconstitution and partial purification of cardiac sarcolemmal Na+/H+ (K+/H+) antiporter by Periyasamy, S M, Paucek, P, Garlid, K D, Askari, A

“…Most of the plasma membrane Na+/H+ antiporters that have been well characterized do not transport K+. Our previous studies showed that cardiac plasma membrane…”
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Elimination of Na+ and GTP regulation of alpha 2-adrenoceptor-agonist interactions in rat kidney membranes by 4,4'-diisothiocyano-2,2'-stilbene disulfonic acid (DIDS) by Periyasamy, S M

“…Pretreatment of rat kidney membranes with 4,4'-diisothiocyano-2,2'-stilbene disulfonic acid (DIDS) did not affect the Bmax but reduced the affinity of the…”
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Ion specificity of cardiac sarcolemmal Na+/H+ antiporter by PERIYASAMY, S. M, KAKAR, S.S, GARLID, K. D, ASKARI, A

“…In bovine cardiac sarcolemmal vesicles, an outward H+ gradient stimulated the initial rate of amiloride-sensitive uptake of 22Na+, 42K+, or 86Rb+. Release of…”
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[3H]Yohimbine binding to human platelet membranes: evidence for high and low affinity binding sites with negative cooperativity by Periyasamy, S M, Somani, P

“…Evidence is presented that [3H]yohimbine binding to human platelet membranes does not follow the simple mass action kinetics. Although [3H]yohimbine binding…”
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