Search Results - "Perino, Matteo"

Chromatin Control of Developmental Dynamics and Plasticity by Perino, Matteo, Veenstra, Gert Jan C.

“…Chromatin structure is intimately connected with gene expression and cell identity. Here we review recent advances in the field and discuss how establishment…”
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Loss of PRC2 subunits primes lineage choice during exit of pluripotency by Loh, Chet H., van Genesen, Siebe, Perino, Matteo, Bark, Magnus R., Veenstra, Gert Jan C.

“…Polycomb Repressive Complex 2 (PRC2) is crucial for the coordinated expression of genes during early embryonic development, catalyzing histone H3 lysine 27…”
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MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding by Perino, Matteo, van Mierlo, Guido, Karemaker, Ino D., van Genesen, Siebe, Vermeulen, Michiel, Marks, Hendrik, van Heeringen, Simon J., Veenstra, Gert Jan C.

“…Abstact Polycomb-mediated repression of gene expression is essential for development, with a pivotal role played by trimethylation of histone H3 lysine 27…”
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Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs by Smits, Arne H, Lindeboom, Rik G H, Perino, Matteo, van Heeringen, Simon J, Veenstra, Gert Jan C, Vermeulen, Michiel

“…While recent developments in genomic sequencing technology have enabled comprehensive transcriptome analyses of single cells, single cell proteomics has thus…”
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Two Functional Axes of Feedback-Enforced PRC2 Recruitment in Mouse Embryonic Stem Cells by Perino, Matteo, van Mierlo, Guido, Loh, Chet, Wardle, Sandra M.T., Zijlmans, Dick W., Marks, Hendrik, Veenstra, Gert Jan C.

“…Polycomb Repressive Complex 2 (PRC2) plays an essential role in gene repression during development, catalyzing H3 lysine 27 trimethylation (H3K27me3). MTF2 in…”
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