Search Results - "Perilla, A"
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Dynamic regulation of Zn(II) sequestration by calgranulin C
Published in Protein science (01-09-2022)“…Calgranulin C performs antimicrobial activity in the human immune response by sequestering Zn(II). This biological function is afforded with the aid of two…”
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Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma
Published in Nature communications (27-04-2018)“…Liquid biopsies including circulating tumor cells (CTCs) and cell-free DNA (cfDNA) have enabled minimally invasive characterization of many cancers, but are…”
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Including the Teaching of Empathy and Emotional Intelligence in Medical Education Curriculum: Imperative yet Challenging
Published in Academic radiology (01-03-2024)Get full text
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All-Atom MD Simulations of the HBV Capsid Complexed with AT130 Reveal Secondary and Tertiary Structural Changes and Mechanisms of Allostery
Published in Viruses (26-03-2021)“…The hepatitis B virus (HBV) capsid is an attractive drug target, relevant to combating viral hepatitis as a major public health concern. Among small molecules…”
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The Integrity of the Intradimer Interface of the Hepatitis B Virus Capsid Protein Dimer Regulates Capsid Self-Assembly
Published in ACS chemical biology (18-12-2020)“…During the hepatitis B virus lifecycle, 120 copies of homodimeric capsid protein assemble around a copy of reverse transcriptase and viral RNA and go on to…”
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Re: formal mentorship in Canadian radiology residency programmes
Published in Clinical radiology (01-12-2023)Get full text
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Experimental Characterization of the Hepatitis B Virus Capsid Dynamics by Solid-State NMR
Published in Frontiers in molecular biosciences (03-01-2022)“…Protein plasticity and dynamics are important aspects of their function. Here we use solid-state NMR to experimentally characterize the dynamics of the 3.5 MDa…”
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Mandibular and temporomandibular morphologic characteristics of patients with suspected unilateral condylar hyperplasia: a CT study
Published in Dental press journal of orthodontics (01-03-2020)“…Facial asymmetry associated with unilateral condylar hyperplasia (UCH) is a complicated clinical condition. The objective of this study was to describe…”
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Computational structural biology: Evolution of the field
Published in Journal of structural biology (01-09-2024)Get full text
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Multiscale Modeling of Hepatitis B Virus Capsid Assembly and Its Dimorphism
Published in ACS nano (27-09-2022)“…Hepatitis B virus (HBV) is an endemic, chronic virus that leads to 800000 deaths per year. Central to the HBV lifecycle, the viral core has a protein capsid…”
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AMBERff at Scale: Multimillion-Atom Simulations with AMBER Force Fields in NAMD
Published in Journal of chemical information and modeling (22-01-2024)“…All-atom molecular dynamics (MD) simulations are an essential structural biology technique with increasing application to multimillion-atom systems, including…”
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Re: Matthias Boschheidgen, Peter Albers, Heinz-Peter Schlemmer, et al. Multiparametric Magnetic Resonance Imaging in Prostate Cancer Screening at the Age of 45 Years: Results from the First Screening Round of the PROBASE Trial. Eur Urol 2024;85:105–11
Published in European urology (01-07-2024)Get full text
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Structure of the Hepatitis B virus capsid quasi-6-fold with a trapped C-terminal domain reveals capsid movements associated with domain exit
Published in The Journal of biological chemistry (01-09-2023)“…Many viruses undergo transient conformational change to surveil their environments for receptors and host factors. In Hepatitis B virus (HBV) infection, after…”
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Integrating 19F Distance Restraints for Accurate Protein Structure Determination by Magic Angle Spinning NMR Spectroscopy
Published in Journal of the American Chemical Society (06-11-2024)“…Traditional protein structure determination by magic angle spinning (MAS) solid-state NMR spectroscopy primarily relies on interatomic distances up to 8 Å,…”
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Integrating 19 F Distance Restraints for Accurate Protein Structure Determination by Magic Angle Spinning NMR Spectroscopy
Published in Journal of the American Chemical Society (06-11-2024)“…Traditional protein structure determination by magic angle spinning (MAS) solid-state NMR spectroscopy primarily relies on interatomic distances up to 8 Å,…”
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Subset of Fluorophores Is Responsible for Radiation Brightening in Viromimetic Particles
Published in The journal of physical chemistry. B (23-09-2021)“…In certain conditions, dye-conjugated icosahedral virus shells exhibit suppression of concentration quenching. The recently observed radiation brightening at…”
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High-Performance Analysis of Biomolecular Containers to Measure Small-Molecule Transport, Transbilayer Lipid Diffusion, and Protein Cavities
Published in Journal of chemical information and modeling (28-10-2019)“…Compartmentalization is a central theme in biology. Cells are composed of numerous membrane-enclosed structures, evolved to facilitate specific biochemical…”
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Molecular dynamics of the viral life cycle: progress and prospects
Published in Current opinion in virology (01-10-2021)“…•Molecular dynamics simulations are the central technique uniting the field of computational virology.•Viruses responsible for recent epidemics and pandemics…”
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Integrative structural biology of HIV-1 capsid protein assemblies: combining experiment and computation
Published in Current opinion in virology (01-06-2021)“…[Display omitted] •Integration of experiment and computation is a powerful means in structural biology.•Integrative approaches enabled the first atomic…”
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