Search Results - "Periasamy, Pravin"

Identification of genes which regulate stroma-dependent in vitro hematopoiesis by Periasamy, Pravin, Tran, Vinson, O'Neill, Helen C

“…Cultured splenic stroma has been shown to support in vitro hematopoiesis in overlaid bone marrow and spleen progenitors. These co-cultures support longterm…”
Get full text

Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis by O'Neill, Helen C, Lim, Hong K, Periasamy, Pravin, Kumarappan, Lavanya, Tan, Jonathan K H, O'Neill, Terence J

“…Spleen stromal lines which support in vitro hematopoiesis are investigated for their lineage origin and hematopoietic support function in vivo. Marker…”
Get full text

MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis by Petvises, Sawang, Periasamy, Pravin, O'Neill, Helen C

“…Splenic stroma overlaid with hematopoietic progenitors supports in vitro hematopoiesis with production of dendritic-like cells. Co-cultures of murine…”
Get full text

Studies on B Cells in the Fruit-Eating Black Flying Fox ( Pteropus alecto) by Periasamy, Pravin, Hutchinson, Paul E, Chen, Jinmiao, Bonne, Isabelle, Shahul Hameed, Shahana Shereene, Selvam, Pavithra, Hey, Ying Ying, Fink, Katja, Irving, Aaron T, Dutertre, Charles-Antoine, Baker, Michelle, Crameri, Gary, Wang, Lin-Fa, Alonso, Sylvie

“…The ability of bats to act as reservoir for viruses that are highly pathogenic to humans suggests unique properties and functional characteristics of their…”
Get full text

Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study by Vellayappan, Balamurugan, Cheong, Dennis, Singbal, Salil, Tey, Jeremy, Yang Soon, Yu, Nang Leong, Cheng, Wong, Alvin, Lwin, Sein, Hung Lee, Chau, Periasamy, Pravin, Lo, Simon, Kumar, Naresh

“…The primary objective was to quantify changes in vascular micro-environment in spinal metastases (SM) patients treated with stereotactic body radiotherapy…”
Get full text

In Vitro Murine Hematopoiesis Supported by Signaling from a Splenic Stromal Cell Line by Lim, Hong Kiat, O’Neill, Helen C., Periasamy, Pravin

“…There are very few model systems which demonstrate hematopoiesis in vitro. Previously, we described unique splenic stromal cell lines which support the in…”
Get full text

Novel splenic antigen-presenting cells derive from a Lin−c-kitlo progenitor by Periasamy, Pravin, Tan, Jonathan K. H., OˈNeill, Helen C.

“…The spleen contains a novel antigen presenting a cell type which develops from endogenous hematopoietic progenitors. The main DC subsets in murine spleen arise…”
Get full text

Splenic stromal niches support hematopoiesis of dendritic-like cells from precursors in bone marrow and spleen by Periasamy, Pravin, Tan, Jonathan K.H, Griffiths, Kristin L, O'Neill, Helen C

“…Objective The aims of this study are to test the ability of stromal cells from murine spleen to support hematopoiesis, to define the tissue source of…”
Get full text

In vitro hematopoiesis reveals a novel dendritic-like cell present in murine spleen by Periasamy, Pravin, O'Neill, Helen C

“…Dendritic cells (DC) are important antigen presenting cells (APC) which induce and control the adaptive immune response. In spleen alone, multiple DC subsets…”
Get more information

Spleen stroma maintains progenitors and supports long-term hematopoiesis by O'Neill, Helen C, Griffiths, Kristin L, Periasamy, Pravin, Hinton, Rebecca A, Petvises, Sawang, Hey, Ying-ying, Tan, Jonathan K H

“…Hematopoietic stem/progenitor cells (HSPC) differentiate in the context of stromal niches producing cells of multiple lineages. Limited success has been…”
Get more information

Spleen as a Site for Hematopoiesis of a Distinct Antigen Presenting Cell Type by Griffiths, Kristin L., O'Neill, Helen C., Periasamy, Pravin, Hinton, Rebecca A., Hey, Ying-Ying, Petvises, Sawang, Tan, Jonathan K. H.

“…While spleen and other secondary tissue sites contribute to hematopoiesis, the nature of cells produced and the environment under which this happens are not…”
Get full text

The role of stroma in hematopoiesis and dendritic cell development by Despars, Geneviève, Tan, Jonathan, Periasamy, Pravin, O'Neill, Helen C

“…Development of the immune system is depicted as a hierarchical process of differentiation from hematopoietic stem cells (HSC) to lineage-committed precursors,…”
Get more information

Stroma-dependent development of two dendritic-like cell types with distinct antigen presenting capability by Periasamy, Pravin, O'Neill, Helen C

“…Novel antigen presenting cells (APCs) have been described in the murine spleen. Cells have a distinct CD11clo CD11bhi MHC-II− CD8α− phenotype as highly…”
Get full text

Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto by Martínez Gómez, Julia María, Periasamy, Pravin, Dutertre, Charles-Antoine, Irving, Aaron Trent, Ng, Justin Han Jia, Crameri, Gary, Baker, Michelle L., Ginhoux, Florent, Wang, Lin-Fa, Alonso, Sylvie

“…The unique ability of bats to act as reservoir for viruses that are highly pathogenic to humans suggests unique properties and functional characteristics of…”
Get full text

Delineation of niches which support hematopoiesis in spleen by Lim, Hong K, Periasamy, Pravin, Petvises, Sawang, O'Neill, Terence, O'Neill, Helen

Get full text

Delineation of precursors in murine spleen that develop in contact with splenic endothelium to give novel dendritic-like cells by Tan, Jonathan K.H., Periasamy, Pravin, O'Neill, Helen C.

“…Hematopoietic cell lineages are best described in terms of distinct progenitors with limited differentiative capacity. To distinguish cell lineages, it is…”
Get full text

Development of two distinct dendritic-like APCs in the context of splenic stroma by Periasamy, Pravin, Petvises, Sawang, O'Neill, Helen C

“…Murine splenic stroma has been found to provide an in vitro niche for hematopoiesis of dendritic-like APC. Two distinct cell types have been characterized. The…”
Get full text

Identification of a novel antigen cross‐presenting cell type in spleen by Tan, Jonathan K. H., Quah, Ben J. C., Griffiths, Kristin L., Periasamy, Pravin, Hey, Ying‐Ying, O’Neill, Helen C.

“…Antigen‐presenting cells (APC), like dendritic cells (DC), are essential for T‐cell activation, leading to immunity or tolerance. Multiple DC subsets each play…”
Get full text

Novel splenic antigen-presenting cells derive from a Lin(-) c-kit(lo) progenitor by Periasamy, Pravin, Tan, Jonathan K H, O'Neill, Helen C

“…The main DC subsets in murine spleen arise from BM-derived precursors. Recently, a novel APC type was described in spleen. To determine if spleen contains the…”
Get full text

Gene signature of stromal cells which support dendritic cell development by Despars, Geneviève, Periasamy, Pravin, Tan, Jonathan, Abbey, Janice, O'Neill, Terence J, O'Neill, Helen C

“…Spleen stromal cells are critical determinants of dendritic cell (DC) development in spleen. The spleen stromal line, namely STX3, supports DC differentiation…”
Get more information