Search Results - "Pergolizzi Jr, Joseph V."

Bracketing Estimation of Intentional Polysubstance Use in the United States by Raffa, Robert B, Pergolizzi, Jr, Joseph V

“…Evidence from diverse sources suggests that persons who have a substance use disorder (SUD) often have problems with one or more additional substances, a…”
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Transdermal Buprenorphine for Acute Pain in the Clinical Setting: A Narrative Review by Pergolizzi, Jr, Joseph V, Magnusson, Peter, LeQuang, Jo Ann, Breve, Frank, Mitchell, Kailyn, Chopra, Maninder, Varrassi, Giustino

“…Transdermal buprenorphine is indicated for chronic pain management, but as its role in the clinical management of acute pain is less clear, this narrative…”
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Bispecific Sigma1R-Antagonist/MOR-Agonist Compounds for Pain by Raffa, Robert B, Pergolizzi, Jr, Joseph V

“…Recent research has significantly advanced an understanding of sigma receptors, which consist of two distinct subtypes designated as S1R and S2R ( and gene…”
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Safety And Efficacy Of The Unique Opioid Buprenorphine For The Treatment Of Chronic Pain by Pergolizzi, Jr, Joseph V, Raffa, Robert B

“…Chronic pain is associated with decreased quality of life and is one of the most common reasons adults seek medical care, making treatment imperative for many…”
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The Use of Peripheral μ-Opioid Receptor Antagonists (PAMORA) in the Management of Opioid-Induced Constipation: An Update on Their Efficacy and Safety by Pergolizzi, Jr, Joseph V, Christo, Paul J, LeQuang, Jo Ann, Magnusson, Peter

“…Peripherally acting μ-opioid receptor antagonists (PAMORAs) constitute a class of drugs which reverse opioid-induced constipation (OIC) with similar opioid…”
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History of Respiratory Stimulants by Peppin, John F, Pergolizzi, Jr, Joseph V, Fudin, Jeffrey, Meyer, Tricia A, Raffa, Robert B

“…The interest in substances that stimulate respiration has waxed and waned throughout the years, intensifying following the introduction of a new class of drugs…”
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Cannabinoid Hyperemesis by Pergolizzi Jr, Joseph V., LeQuang, Jo Ann, Bisney, John F.

“…Cannabinoid hyperemesis syndrome (CHS) is a paradoxical condition in which a long-term cannabis user suffers an episode of intractable vomiting that may last…”
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Exposure to Potential CYP450 Pharmacokinetic Drug-Drug Interactions among Osteoarthritis Patients: Incremental Risk of Multiple Prescriptions by Pergolizzi Jr, Joseph V., Labhsetwar, Sumedha A., Puenpatom, R. Amy, Joo, Seongjung, Ben-Joseph, Rami, Summers, Kent H.

“…Patients taking more than one drug metabolized through the cytochrome P450 (CYP450) enzyme system experience a drug–drug exposure (DDE), which puts them at…”
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A Novel Formulation of Ketorolac Tromethamine (NTM-001) in Continuous Infusion in Adults with and without Renal Impairment: A Randomized Controlled Pharmacologic Study by Pergolizzi, Joseph V., Batra, Amanjot, Schmidt, William K.

“…Introduction There is a medical need for a safe, effective nonopioid postoperative analgesic for older subjects, including those with mild to moderate renal…”
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A Randomized Controlled Trial of a Novel Formulation of Ketorolac Tromethamine for Continuous Infusion (NTM-001) in Healthy Volunteers by Pergolizzi, Joseph V., Batra, Amanjot, Schmidt, William K.

“…Introduction There is an urgent unmet medical need for a safe, effective, nonopioid analgesic agent for postoperative pain control. Methods This first-in-man…”
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Good clinical practice guide for opioids in pain management: the three Ts – titration (trial), tweaking (tailoring), transition (tapering) by Coluzzi, Flaminia, Taylor, Robert, Pergolizzi, Joseph V., Mattia, Consalvo, Raffa, Robert B.

“…Achieving good clinical practice in the use of opioids as part of a comprehensive pain management regimen can face significant challenges. Despite guidelines…”
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Bone fractures during the time of coronavirus by Umeda‐Raffa, Sumiyo, Pergolizzi Jr, Joseph V., Raffa, Robert B.

“…What is known and Objective In response to rapid spread of coronavirus (SARS‐CoV‐2) and lack of vaccine or effective treatment for COVID‐19 disease,…”
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Potential neurological manifestations of COVID-19: a narrative review by Pergolizzi, Joseph V., Raffa, Robert B., Varrassi, Giustino, Magnusson, Peter, LeQuang, Jo Ann, Paladini, Antonella, Taylor, Robert, Wollmuth, Charles, Breve, Frank, Chopra, Maninder, Nalamasu, Rohit, Christo, Paul J.

“…Neurological manifestations are increasingly reported in a subset of COVID-19 patients. Previous infections related to coronaviruses, namely Severe Acute…”
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Opioid Formulations Designed to Resist/Deter Abuse by Raffa, Robert B., Pergolizzi, Joseph V.

“…Physicians who prescribe opioid analgesics for patients with moderate to severe chronic pain face a balancing act in the wake of the current publicity…”
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Ketorolac Tromethamine - Routes and Clinical Implications by Vadivelu, Nalini, Gowda, Anusha M., Urman, Richard D., Jolly, Suneil, Kodumudi, Vijay, Maria, Monisa, Taylor Jr, Robert, Pergolizzi Jr, Joseph V.

“…Opioids have long been used for analgesic purposes for a wide range of procedures. However, the binding of these drugs to opiate receptors has created various…”
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COVID-19 and NSAIDS: A Narrative Review of Knowns and Unknowns by Pergolizzi, Joseph V., Varrassi, Giustino, Magnusson, Peter, LeQuang, Jo Ann, Paladini, Antonella, Taylor, Robert, Wollmuth, Charles, Breve, Frank, Christo, Paul

“…Concern about the appropriate role of nonsteroidal anti-inflammatory drugs (NSAIDs) in COVID-19 speculate that NSAIDs, in particular ibuprofen, may upregulate…”
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Statins and muscle pain by Pergolizzi, Jr, Joseph V, Coluzzi, Flaminia, Colucci, Robert D, Olsson, Hanna, LeQuang, Jo Ann, Al-Saadi, Jonathan, Magnusson, Peter

“…: Statins remain among the most frequently prescribed drugs and constitute a cornerstone in the prevention of cardiovascular disease. However, muscle symptoms…”
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Acetaminophen (Paracetamol) Oral Absorption and Clinical Influences by Raffa, Robert B., Pergolizzi Jr, Joseph V., Taylor Jr, Robert, Decker, John F., Patrick, Jeffrey T.

“…Acetaminophen (paracetamol) is a widely used nonopioid, non‐NSAID analgesic that is effective against a variety of pain types, but the consequences of overdose…”
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The concern about ACE/ARB and COVID-19: Time to hold your horses by Pergolizzi, Joseph V., Varrassi, Giustino, Magnusson, Peter, LeQuang, Jo Ann, Leopoulou, Marianna, Paladini, Antonella, Taylor, Robert, Wollmuth, Charles, Breve, Frank

“…Concern about coronavirus 2019 (COVID-19) morbidity and mortality has drawn attention to the potential role of angiotensin-converting enzyme (ACE) inhibitors…”
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The role of cannabinoids in pain control: the good, the bad, and the ugly by Pergolizzi, Jr, Joseph V, Lequang, Jo A, Taylor, Jr, Robert, Raffa, Robert B, Colucci, Daniel

“…Cannabinoids appear to possess many potential medical uses, which may extend to pain control. A narrative review of the literature has found a variety of…”
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