Search Results - "Perfect, J. R"

Resistance to Antifungal Agents: Mechanisms and Clinical Impact by Kanafani, Zeina A., Perfect, John R.

“…Despite advances in preventive, diagnostic, and therapeutic interventions, invasive fungal infections cause significant morbidity and mortality in…”
Get full text

Zygomycosis : the re-emerging fungal infection by CHAYAKULKEEREE, M, GHANNOUM, M. A, PERFECT, J. R

“…Invasive fungal infections are major medical complications in immunocompromised patients. The recent rise in the incidence of cancer and the increased use of…”
Get full text

The Impact of Culture Isolation of Aspergillus Species: A Hospital-Based Survey of Aspergillosis by Perfect, J. R., Cox, G. M., Lee, J. Y., Kauffman, C. A., de Repentigny, L., Chapman, S. W., Morrison, V. A., Pappas, P., Hiemenz, J. W., Stevens, D. A.

“…The term “aspergillosis” comprises several categories of infection: invasive aspergillosis; chronic necrotizing aspergillosis; aspergilloma, or fungus ball;…”
Get full text

Management of an Outbreak of Exophiala dermatitidis Bloodstream Infections at an Outpatient Oncology Clinic by Vasquez, Amber, Zavasky, D, Chow, N A, Gade, L, Zlatanic, E, Elkind, S, Litvintseva, A P, Pappas, P G, Perfect, J R, Revankar, S, Lockhart, S R, Chiller, T, Ackelsberg, J, Vallabhaneni, S

“…We report the presentation and management of 17 cases of Exophiala dermatitidis and Rhodotorula mucilaginosa bloodstream infections caused by a compounded…”
Get full text

Pulmonary cryptococcosis in patients without HIV infection: factors associated with disseminated disease by Baddley, J. W., Perfect, J. R., Oster, R. A., Larsen, R. A., Pankey, G. A., Henderson, H., Haas, D. W., Kauffman, C. A., Patel, R., Zaas, A. K., Pappas, P. G.

“…Cryptococcus neoformans is an uncommonly recognized cause of pneumonia in HIV-negative patients. Because of its propensity to disseminate to the meninges and…”
Get full text

Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood by Schell, W. A., Benton, J. L., Smith, P. B., Poore, M., Rouse, J. L., Boles, D. J., Johnson, M. D., Alexander, B. D., Pamula, V. K., Eckhardt, A. E., Pollack, M. G., Benjamin, D. K., Perfect, J. R., Mitchell, T. G.

“…Species of Candida frequently cause life-threatening infections in neonates, transplant and intensive care unit (ICU) patients, and others with compromised…”
Get full text

Practice Guidelines for the Management of Cryptococcal Disease by Saag, Michael S., Graybill, Richard J., Larsen, Robert A., Pappas, Peter G., Perfect, John R., Powderly, William G., Sobel, Jack D., Dismukes, William E.

Get full text

Infections Due to Aspergillus terreus: A Multicenter Retrospective Analysis of 83 Cases by Steinbach, William J., Benjamin, Daniel K., Kontoyiannis, Dimitrios P., Perfect, John R., Lutsar, Irja, Marr, Kieren A., Lionakis, Michail S., Torres, Harrys A., Jafri, Hasan, Walsh, Thomas J.

“…Current in vitro and in vivo data indicate that invasive aspergillosis due to Aspergillus terreus is resistant to treatment with amphotericin B. Because little…”
Get full text

Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans by MITCHELL, T. G, PERFECT, J. R

“…Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
Get full text

Autophagy is redundant for the host defense against systemic Candida albicans infections by Smeekens, S. P., Malireddi, R. K., Plantinga, T. S., Buffen, K., Oosting, M., Joosten, L. A. B., Kullberg, B. J., Perfect, J. R., Scott, W. K., van de Veerdonk, F. L., Xavier, R. J., van de Vosse, E., Kanneganti, T.-D., Johnson, M. D., Netea, M. G.

“…Autophagy has been demonstrated to play an important role in the immunity against intracellular pathogens, but very little is known about its role in the host…”
Get full text

Identification and Characterization of an SKN7 Homologue in Cryptococcus neoformans by Wormley, F. L, Heinrich, G, Miller, J. L, Perfect, J. R, Cox, G. M

“…Cryptococcus neoformans is an encapsulated fungal pathogen that primarily infects the central nervous system of immunocompromised individuals, causing…”
Get full text

Combination antifungal therapy: what can and should we expect? by JOHNSON, M. D, PERFECT, J. R

“…Invasive fungal infections are associated with significant morbidity and mortality among immunocompromised patients. Recent advances in antifungal development…”
Get full text

Posaconazole as salvage treatment of invasive fungal infections in patients with underlying renal impairment by Hachem, R. Y., Langston, A. A., Graybill, J. R., Perfect, J. R., Pedicone, L. D., Patino, H., Raad, I. I.

“…Objectives The aim of this study is to determine the efficacy and safety of posaconazole in patients with underlying renal impairment. Patients and methods We…”
Get full text

Cryptococcus neoformans Gene Expression during Experimental Cryptococcal Meningitis by Steen, B R, Zuyderduyn, S, Toffaletti, D L, Marra, M, Jones, S J M, Perfect, J R, Kronstad, J

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans by Salas, S D, Bennett, J E, Kwon-Chung, K J, Perfect, J R, Williamson, P R

“…To assess the relationship between melanin production by Cryptococcus neoformans and virulence on a molecular basis, we asked: (a) is CNLAC1, the laccase…”
Get full text

The impact of caspase-12 on susceptibility to candidemia by Rosentul, D. C., Plantinga, T. S., Scott, W. K., Alexander, B. D., van de Geer, N. M. D., Perfect, J. R., Kullberg, B. J., Johnson, M. D., Netea, M. G.

“…Candida is one of the leading causes of sepsis, and an effective host immune response to Candida critically depends on the cytokines IL-1β and IL-18, which…”
Get full text

Comparative Pharmacokinetics of Voriconazole Administered Orally as either Crushed or Whole Tablets by ASHLEY, E. S. Dodds, ZAAS, A. K, FANG, A. F, DAMLE, B, PERFECT, J. R

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds by DEL POETA, M, SCHELL, W. A, PERFECT, J. R

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
Get full text

Immune Reconstitution Syndrome and Exacerbation of Infections after Pregnancy by Singh, Nina, Perfect, John R.

“…Pregnancy is a state of subtle immunosuppression characterized by physiologic suppression of proinflammatory host responses that are meant to promote embryonic…”
Get full text

Limitations of antifungal prophylaxis in preventing invasive Candida surgical site infections after liver transplant surgery by Carugati, M, Arif, S, Yarrington, M E, King, L Y, Harris, M, Evans, K, Barbas, A S, Sudan, D L, Perfect, J R, Miller, R A, Alexander, B D

“…Invasive primary surgical site infections (IP-SSIs) are a common complication of liver transplantation, and targeted antifungal prophylaxis is an efficient…”
Get full text